Results 61 to 70 of about 74,639 (286)

Machine Learning Model for Predicting Hepatocellular Carcinoma Development in Patients With Hepatitis B Virus‐Related Cirrhosis Receiving Antiviral Therapy

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Few prediction models have been specifically designed to evaluate the risk of hepatocellular carcinoma (HCC) in patients with chronic hepatitis B and cirrhosis. This study aimed to develop a machine learning‐based prediction model to assess the risk of developing HCC in patients with hepatitis B virus (HBV)‐related cirrhosis undergoing nucleos(
Pao‐Yuan Huang   +4 more
wiley   +1 more source

Super- and Coinfection: The Two Extremes [PDF]

open access: yes, 2002
As is well known, the conventional wisdom that successful parasites have to become benign is not based on exact evolutionary analysis. Rather than minimizing virulence, selection works to maximize a parasite's reproduction ratio (see Box 9.1). If the rate of transmission is linked to virulence (defined here as increased mortality due to infection ...
Nowak, M.A., Sigmund, K.
openaire   +3 more sources

Memory Th17 cell-mediated protection against lethal secondary pneumococcal pneumonia following influenza infection

open access: yesmBio, 2023
Streptococcus pneumoniae (Sp) frequently causes secondary pneumonia after influenza A virus (IAV) infection, leading to high morbidity and mortality worldwide. Concomitant pneumococcal and influenza vaccination improves protection against coinfection but
Yong Li   +10 more
doaj   +1 more source

Investigating Tuberculosis Dynamics Under Various Control Strategies: A Comprehensive Analysis Using Real Statistical Data

open access: yesMathematical Methods in the Applied Sciences, EarlyView.
ABSTRACT In the present investigation, a mathematical model with vaccination, treatment, and environmental impact under real data is presented. Initially, we present the model without any interventions, followed by an examination of its equilibrium points.
Bashir Al‐Hdaibat   +4 more
wiley   +1 more source

Analysis of the HBV and TB Coinfection Model With Optimal Control Strategies and Cost-Effectiveness

open access: yesDiscrete Dynamics in Nature and Society
The coinfection of HBV and TB diseases affects millions of individuals throughout the nations in the world. The main objective of this study is to formulate and analyze the HBV and TB coinfection dynamical system, investigate the impact of time-dependent
Shewafera Wondimagegnhu Teklu   +1 more
doaj   +1 more source

The Interplay Between Schistosomiasis and Hepatitis C Virus: Battling on Two Fronts

open access: yesInfectious Diseases & Immunity
. Schistosomiasis is a prevalent health issue in numerous countries in Africa, Asia, and South America. Data regarding the coinfection of schistosomiasis with hepatitis C virus (HCV) is limited, yet this coinfection is prevalent in regions where ...
Nahed A Makhlouf   +4 more
doaj   +1 more source

Single and dual RPA‐CRISPR/Cas assays for point‐of‐need detection of Stewart's wilt pathogen (Pantoea stewartii subsp. stewartii) of corn and Maize dwarf mosaic virus

open access: yesPest Management Science, Volume 81, Issue 4, Page 1988-1999, April 2025.
Schematic diagram of the single and dual RPA‐CRISPR/Cas12a/13a diagnostic assays for the detection of Pantoea stewartii subsp. stewartii and Maize dwarf mosaic virus. The validated assays provide a useful and sensitive molecular tool for detecting two quarantine pathogens of maize within a minimal resource framework suitable for fast‐tracking the ...
Qian Tian   +6 more
wiley   +1 more source

Comprehensive evaluation of metagenomic next‐generation sequencing for pathogen identification in patients with suspected infection: Establishment of a standardized validation workflow

open access: yesVIEW, EarlyView.
Comprehensive evaluation of metagenomic next‐generation sequencing for pathogen identification in patients with suspected infection: Establishment of a standardized validation workflow. Abstract Metagenomic next‐generation sequencing (mNGS) enables unbiased identification of pathogens directly from clinical specimens. Despite its growing application in
Wen Shu   +11 more
wiley   +1 more source

Epidemic manifestations of HIV combined with chronic viral hepatitis in the Far Eastern Federal District

open access: yesИнфекция и иммунитет
Coinfection is one of the most complex public health issues and is challenging both in choosing treatment strategy and in implementing epidemiological surveillance.
Elena A. Bazykina   +3 more
doaj   +1 more source

Iflaviruses in arthropods: when small is mighty

open access: yesInsect Science, EarlyView.
Many arthropod species harbor iflaviruses, which often cause covert (asymptomatic) infections, but may still affect host fitness. We review the impact of iflaviruses on arthropod fitness, immunity, behaviour as well as the iflavirus’ host range, transmission, tissue tropism and the interactions with other microorganisms within arthropods.
Annamaria Mattia   +3 more
wiley   +1 more source

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