Results 91 to 100 of about 16,654 (233)
ESC Heart Failure, Volume 12, Issue 2, Page 942-954, April 2025.Abstract The immune system has long been recognized as a key driver in the progression of heart failure (HF). However, clinical trials targeting immune effectors have consistently failed to improve patient outcome across different HF aetiologies. The activation of the immune system in HF is complex, involving a broad network of pro‐inflammatory and ...
Johann Roessler +4 more
wiley +1 more source
International Journal of Nanomedicine, 2011 Qi Shen, Ying Wang, Yi ZhangSchool of Pharmacy, Shanghai Jiao Tong University, Dongchuan Road 800, Shanghai 200240, People’s Republic of ChinaAbstract: The effect of eugenol on colchicine transport across an isolated rat intestinal membrane was
Shen Q, Wang Y, Zhang Y
doaj
ESC Heart Failure, Volume 12, Issue 2, Page 1427-1436, April 2025.Abstract Background and objectives Initially described as a benign acute cardiomyopathy, Takotsubo syndrome has been linked to elevated mortality rates. Emerging evidence suggests that unresolved myocardial inflammation may contribute to this adverse prognosis.
Loïc Faucher +12 more
wiley +1 more source
Inhibition of free fatty acid mobilization by colchicine
Journal of Lipid Research, 1974 Segments of epididymal adipose tissue from normal male rats were incubated with micromolar concentrations of colchicine for different periods of time up to 4 hr, and the mobilization of free fatty acids (FFA) was measured during a subsequent reincubation.
Richard J. Schimmel
doaj +1 more source
TRIM31–LOX‐1 Axis: A Novel Therapeutic Frontier in Atherosclerosis
iNew Medicine, EarlyView.ABSTRACT Atherosclerosis, driven by a vicious cycle of lipid accumulation and chronic inflammation, underlies most cardiovascular diseases. Macrophages exacerbate this process by internalizing oxidized low‐density lipoprotein (oxLDL), forming foam cells, and releasing inflammatory mediators. A recent study published in Circulation identified the TRIM31–
Qian Zhang, Cheng Xue Qin
wiley +1 more source
Colchicine alleviates steroid-induced Hyperglycemia and Dyslipidemia: Targeting Pyroptosis and Oxidative stress [PDF]
Zagazig University Medical JournalBackground Steroid-induced hyperglycemia (SIH) is one of the most important side effects of glucocorticoids. Colchicine is a medication used to manage inflammation with not yet fully understood mechanisms.
Marwa M. Ahmad +5 more
doaj +1 more source
DAPSONE AS AN ALTERNATIVE THERAPY IN CHILDREN WITH FAMILIAL MEDITERRANEAN FEVER [PDF]
Objective: Familial Mediterranan Fever is an hereditary autoinflammatory disease that presents with recurrent febrile attacks and poly serositis. Colchicine is the only known treatment in this diease.
صالح زاده, فرهاد +2 more
core
, 2014 Colchicine is an alkaloid extracted from autumnal Colchicum plant which is used primarily for its anti-inflammatory therapy effect. Acute intoxication with colchicine is uncommon but often severe and results in multiple visceral organ dysfunctions.
Saïd Boujraf +3 more
core +1 more source
Juvenile Gangrenous Vasculitis of the Scrotum or Scrotum Lipschütz Ulcers
JEADV Clinical Practice, EarlyView.ABSTRACT Lipschütz genital ulcers are traditionally described in adolescent females and often linked to acute viral infections. Their male counterpart remains poorly characterised. We report a 59‐year‐old man with sudden onset of unilateral necrotic ulcers on the scrotum and inguinal region following a brief febrile episode and mild pharyngitis ...
Francesco Bellinato +2 more
wiley +1 more source
Hypersensitivity to Colchicine [PDF]
Annals of the Rheumatic Diseases, 1947 J G, Macleod, L, Phillips
openaire +3 more sources