Results 101 to 110 of about 16,654 (233)

Four children with colchicine poisoning

, 2004
Colchicine poisoning is a rare event. It is characterized by multiorgan involvement and by poor prognosis associated with overdose. In this article we present four children with colchicine poisoning to emphasize that colchicine poisoning has a large ...
Caksen, H, Akgun, C, Tuncer, O, Atas, B, Kirimi, E, Odabas, D   +5 more
core   +1 more source

Accidental plant poisonings in France: Lessons from a decade of national toxicovigilance

PLANTS, PEOPLE, PLANET, EarlyView.
Accidental plant poisonings reveal how modern societies are losing everyday botanical knowledge once central to food and health safety. By analyzing a decade of French toxicovigilance data, this study shows that most severe cases arise from plant misidentification or misguided self‐medication.
Gaël Le Roux, Adrien Maillot, Sylvie Michel, Jérôme Langrand, Sébastien Larréché, Christine Tournoud, David Boels, Magali Labadie, Nicolas Delcourt, Nathalie Paret, Luc de Haro, Sandra Sinno‐Tellier   +11 more
wiley   +1 more source

Mutagenic and physiological impacts of colchicine on growth, flowering behavior, and ISSR-based genetic variability in Calendula officinalis L

BMC Plant Biology
Purpose Stimulating flowering ability is the main purpose of commercial development of ornamental plants. Colchicine could contribute to improve flowering and related physiological processes; however its potential mode on marigold (Calendula officinalis)
Makka A. Hassan, Hani S. Saudy, Mohammed Hewidy, Heba El-Sammak   +3 more
doaj   +1 more source

Comprehensive Transcriptomic and m6A Epitranscriptomic Analysis Reveals Colchicine-Induced Kidney Toxicity via DNA Damage and Autophagy in HK2 Cells

Toxins
Colchicine is commonly prescribed for inflammation and gout, but its nephrotoxicity and underlying mechanisms remain incompletely understood. The objective of this research was to clarify the association between m6A methylation modifications and ...
Kun Tian, Jiaxin Wen, Dongcheng Zhang, Jiaxuan Lin, Lixiang Weng, Lele Yang, Wei Zhao, Chutao Li, An Zhu   +8 more
doaj   +1 more source

Bioactive Natural Products in Cardiovascular Disease: Focus on Thrombotic Events

Phytotherapy Research, EarlyView.
An overview of the role of natural products (NP) in cardiovascular disease prevention, highlighting key mechanisms of action: including antiplatelet, antithrombotic, anti‐inflammatory, and antioxidant effects. Additionally, it illustrates the integration of diet–drug interactions, nutritional epigenetics, and the role of artificial intelligence in ...
Maria Nektaria Magkoulia, Despoina Pantazi   +1 more
wiley   +1 more source

Multitarget Regulatory Mechanisms and Research Advances of Plant‐Derived Bioactive Ingredients in Hypertension Prevention and Management

Phytotherapy Research, EarlyView.
Schematic overview of the multi‐target and multi‐pathway mechanisms of PDBI in the prevention and management of hypertension. ABSTRACT Hypertension remains a major global risk factor for cardiovascular diseases, yet current treatments face challenges such as suboptimal blood pressure control and inadequate organ protection.
Qiqi Deng, Yonglin Zhang, Jing Pan, Jing Luo, Hualin Sun, Chaonian Li, Li Li   +6 more
wiley   +1 more source

Severe hypertriglyceridemia and colchicine intoxication following suicide attempt

, 2017
Shaul Lev,1 David Snyder,2 Carmil Azran,3 Victor Zolotarsky,1 Arik Dahan4 1Intensive Care Unit, Rabin Medical Center, Petah-Tikva, 2Sackler School of Medicine NY/American Program, Tel-Aviv University, Tel Aviv, 3Clinical Pharmacy, Herzliya Medical ...
Azran C, Zolotarsky V, Dahan A, Snyder D, Lev S   +4 more
core  

Case series: Kikuchi‐Fujimoto disease with diagnostic overlap

Rheumatology &Autoimmunity, EarlyView.
Kikuchi‐Fujimoto disease (KFD) is a rare, self‐limiting necrotizing lymphadenitis that poses significant diagnostic challenges due to its overlap with tuberculosis, systemic lupus erythematosus (SLE), and malignancy. We present four cases highlighting distinct diagnostic complexities: KFD mimicking tuberculosis with concomitant latent TB infection and ...
Ecem Kalemoglu, Ming Zheng, Danny Arias, Andreina M. Paulino, Aisha Niaz, James Devlin, Valentin Marian   +6 more
wiley   +1 more source

Role of defensins in immunothrombosis

Rheumatology &Autoimmunity, EarlyView.
Defensins are important proteins that link the immune system and blood clotting, playing a key role in immunothrombosis. α‐defensins mainly come from neutrophils, while β‐defensins are produced by epithelial cells and platelets. These proteins help form blood clots in several ways: they slow down clot breakdown (fibrinolysis), activate platelets, and ...
Yuebing Wang, Guijuan Guo, Xiangjun Liu, Xiaoyu Chen, Wenqiong Wang, Patapong Towiwat, Ru Li, Chun Li   +7 more
wiley   +1 more source

Current Advances of Treatments, Therapeutic Targets, Biomarkers, Novel Drugs, and Machine Learning for Hypopharyngeal Squamous Cell Carcinoma

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Hypopharyngeal squamous cell carcinoma (HSCC) is an aggressive subtype of head and neck squamous cell carcinoma with insidious onset, early metastasis, and dismal prognosis. Conventional multimodal therapy achieves limited survival benefit, highlighting an urgent need for refined precision strategies.
Ce Li, Rui Guan, Rui‐Jie Jiao, Zhi‐Jie Bi, Yang Fu, Yin Wang, Chen‐Yang Xu, Ye Qian, Ran Wei, Sheng‐Da Cao, Wen‐Ming Li, Dong‐Min Wei, Da‐Peng Lei   +12 more
wiley   +1 more source