The hfPSC‐LCs could be established from naïve hESCs, conventional hESCs, hiPSCs, and human blastocysts. The hfPSC‐LCs hold robust capacity for three germ layers, hPGCLCs, and hALPCs. ABSTRACT Human embryos undergo pivotal morphogenetic remodelling shortly after implantation. The understanding of this crucial stage is severely impeded by the scarcity of
Xiaoxiao Wang +11 more
wiley +1 more source
Colchicine Inhibits Chemokine Production in Monosodium Urate-Stimulated Innate Immune Cells. [PDF]
Merlo Pich LM +5 more
europepmc +1 more source
Beyond Venous Inflammation: Vessel Wall Imaging of Intracranial Arteries in Neuro‐Behçet's Syndrome
ABSTRACT Background Neuro‐Behçet syndrome (NBS) is a heterogeneous inflammatory disorder in which venous involvement is well recognized, while intracranial arterial pathology remains insufficiently characterized. Conventional luminal imaging methods are limited in detecting early or isolated arterial wall abnormalities.
Esra Kochan Kizilkilic +9 more
wiley +1 more source
Abstract Type 2 diabetes (T2D) is a major global health concern strongly associated with atherosclerosis and subsequent macrovascular complications. These complications are the leading cause of death among T2D patients. Despite a decline in cardiovascular events over the last decade, individuals with T2D still have an approximately doubled risk ...
Dania Al‐Sharify +2 more
wiley +1 more source
Cardiovascular Outcomes with Colchicine in Coronary Artery Disease and HFpEF: A Propensity-Matched TriNetX Analysis. [PDF]
Ahmed F +16 more
europepmc +1 more source
ABSTRACT Doubled haploid (DH) technology has been widely adopted in maize (Zea mays L.) breeding programs due to its ability to reduce breeding cycle time and optimize costs. Early ploidy identification is essential for maximizing the efficiency of DH production, particularly prior to chromosome doubling.
Mariana Martins Marcondes +7 more
wiley +1 more source
The effect of colchicine on micronutrients in children with newly diagnosed familial Mediterranean fever. [PDF]
Kaba Ö +5 more
europepmc +1 more source
CaV1.2 dynamics in native male arterial myocytes
Abstract figure legend Proposed model of microtubule‐dependent CaV1.2 reorganization in vascular disease. Schematic illustration of microtubule‐mediated delivery and stabilization of CaV1.2 channels into enlarged plasma membrane clusters in response to Ang II or hyperglycaemia, promoting cooperative gating and enhanced Ca2+ influx. Abstract L‐type CaV1.
Miguel Martin‐Aragon Baudel +9 more
wiley +1 more source
A Randomized Trial to Investigate the Effects of Low-Dose Colchicine in Patients with Hypertension: Rationale and Design of the COlchicine and HypERtENsion Trial (COHERENT). [PDF]
Langhoff AF +6 more
europepmc +1 more source
Immersion Frequency Optimisation and Species-Specific Metabolic Profiles of Colchicum autumnale and Colchicum bivonae in Temporary Immersion Systems. [PDF]
Dincheva I +6 more
europepmc +1 more source

