Results 121 to 130 of about 78,062 (255)

Acute colchicine intoxication complicated with complete AV block

The Turkish Journal of Pediatrics, 2015
Colchicine, is an old and well-known drug, used for treatment of rheumatic diseases. Nausea, vomiting, abdominal pain, and diarrhea are the clinical symptoms of colchicine poisoning. Cardiotoxicity can lead to mortality.
İlker Ertuğrul, Emine Polat, Senem Özgür, Vehbi Doğan, Tamer Yoldaş, Şeyma Akşin, Utku Arman Örün, Selmin Karademir   +7 more
doaj  

Treatment of Licorice Seeds with Colchicine: Changes in Seedling DNA Levels and Anthocyanin and Glycyrrhizic Acid Contents of Derived Callus Cultures

Natural Product Communications, 2012
The use of colchicine to induce polyploids increases secondary metabolite production potential and has been used for many years for the production of valuable compounds in plants.
Françoise Bernard, Nahid Moghbel, Sahar Hassannejad   +2 more
doaj   +1 more source

Early Discrimination of Maternal Haploid and Diploid Maize (Zea mays L.) Seedlings Using Morphological Traits and Random Forest Classifier

Plant Breeding, EarlyView.
ABSTRACT Doubled haploid (DH) technology has been widely adopted in maize (Zea mays L.) breeding programs due to its ability to reduce breeding cycle time and optimize costs. Early ploidy identification is essential for maximizing the efficiency of DH production, particularly prior to chromosome doubling.
Mariana Martins Marcondes, Matheus Lucas Schuck, Victor Hugo Garcia, Robson Marcelo Rossi, Vanderlei Aparecido de Lima, Rodrigo Gomes, Carlos Alberto Scapim, Marcos Ventura Faria   +7 more
wiley   +1 more source

Multi‐Omics Analyses Reveal the Red and Far‐Red Light Combination Enhancing Heterologous Protein and Metabolite Production in Nicotiana benthamiana

Plant, Cell &Environment, EarlyView.
ABSTRACT Transient expression of exogenous protein in Nicotiana benthamiana leaves via agroinfiltration offers a rapid and efficient platform for functional gene discovery and heterologous production of valuable eukaryotic proteins and metabolites. Though light quality is an important factor for plant photomorphogenesis, its impact on the efficiency of
Yating Zhang, Fengjiao Wang, Ran Du, Tao Li, Shaoqun Zhou, Jianbin Yan, Wei Li   +6 more
wiley   +1 more source

Towards a cure for gout: A two‑stage treat‐to‐target strategy from inflammation control to structural remission

Rheumatology &Autoimmunity, EarlyView.
Jiani Liu, Ziwen Xu, Wenxi Cui, Man Lu, Qingqing Zhang, Wenxia Lin, Shixian Chen, Weikai Lin, Guichuan Lai, Meng Li, Juan Li   +10 more
wiley   +1 more source

Dermatologic Findings of RELA‐Associated Autoinflammatory Disease

Pediatric Dermatology, EarlyView.
ABSTRACT Variants in the gene RELA have been implicated in a monogenic, hereditary form of Behcet's‐like syndrome. This case series describes the dermatologic manifestations of three patients with identified RELA‐associated autoinflammatory disease.
Elizabeth Nourse, Vidya Sivaraman, Catherine G. Chung, Shoghik Akoghlanian, Esteban Fernandez Faith   +4 more
wiley   +1 more source

One day of environment‐induced heat stress causes injury to the murine kidney

Experimental Physiology, EarlyView.
Abstract Environment‐induced heat stress (EIHS) results from sustained body temperature elevation owing to prolonged exposure to heat and humidity. We hypothesized that EIHS would cause kidney injury and cellular dysfunction. To test this hypothesis, female C57 mice were exposed to EIHS (n = 14; 37.6°C, 42.0% relative humidity) or thermoneutral (TN ...
Melissa Roths, Alyona Michael, Zachary J. Schlader, Joshua T. Selsby   +3 more
wiley   +1 more source

Patients Prescribed Anakinra for Acute Gout Have Baseline Increased Burden of Hyperuricemia, Tophi, and Comorbidities, and Ultimate All-Cause Mortality. [PDF]

, 2019
Objective:The interleukin-1 (IL-1) receptor antagonist anakinra is an effective, off-label option in acute gout flares, when conventional therapy options are narrowed.
Pedersen, Brian, Sharma, Ena, Terkeltaub, Robert   +2 more
core  

Mitophagy in skeletal muscle: Impact of ageing, exercise and disuse

Experimental Physiology, EarlyView.
Abstract Skeletal muscle plays an important role in whole‐body health, quality of life and regulation of metabolism. The maintenance of a healthy mitochondrial pool is imperative for the preservation of skeletal muscle quality and is mediated through mitochondrial quality control consisting of mitochondrial turnover mediated by a balance between ...
Anastasiya Kuznyetsova, David A. Hood
wiley   +1 more source

Hypoxia and the cytoskeleton

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic outlining the activation of hypoxia‐sensitive pathways, the influence of hypoxia and associated pathways on the cytoskeleton, and the impact of these on disease progression. Abstract A highly‐regulated and dynamic cytoskeleton is vital for functional cellular physiology and the maintenance of homeostasis.
Darragh Flood, Cormac T. Taylor
wiley   +1 more source