Results 111 to 120 of about 16,654 (233)

Colchicine intoxication: a report of two suicide cases

open access: yes, 2013
Abdulsamet Erden,1 Hatice Karagoz,1 Hasan Hüseyin Gümüscü,1 Samet Karahan,1 Mustafa Basak,1 Fatma Aykas,1 Kadir Bulut,1 Ali Cetinkaya,1 Deniz Avci,1 Orhan Kürsat Poyrazoglu2 1Internal Medicine Department, 2Gastroenterology ...
Karahan S   +9 more
core  

Analysis of polymorphisms in the colchicine binding site of tubulin in colchicine-resistant familial Mediterranean fever patients.

open access: yes, 2020
Familial Mediterranean fever is a hereditary autoinflammatory syndrome. The typical treatment for the disease is colchicine. However, a subset of patients are not responsive to colchicine.
Ustabas, G   +5 more
core   +1 more source

Colchicine in recently hospitalized patients with COVID-19: A randomized controlled trial (COL-COVID) [PDF]

open access: yes, 2021
©2021. Pascual-Figal et al. This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/ terms.php and incorporate the Creative Commons Attribution – Non Commercial ...
Bernal, Enrique   +13 more
core  

COLCHICINE-INDUCED HEPATOTOXICITY

open access: yes, 2020
Colchicine is an agent that is used for the treatment of inflammatory disease Such as Familial Mediterranean Fever (FMF) and acute gouty arthritis.
Isler, Mehmet   +4 more
core  

The Impact of Common Medications on Male Fertility: An Updated Systematic Review

open access: yesAndrology, EarlyView.
ABSTRACT Background Compared with those of cytotoxic treatments, the potential effects of common medications on the fertility of men trying to conceive currently or planning to conceive in the future are less well described. The use of common medications may modify the gonadotropic axis, spermatogenesis, and epididymal maturation or alter male ...
Lina Jebli   +7 more
wiley   +1 more source

Cardiovascular toxicity from immune checkpoint inhibitor therapy: an inflammatory continuum

open access: yesBritish Journal of Pharmacology, EarlyView.
Immune checkpoint inhibitor (ICI) therapy has markedly improved outcomes in advanced malignancies but has also revealed a distinct spectrum of cardiovascular immune‐related adverse events. Myocarditis represents the most severe manifestation, while non‐inflammatory left ventricular dysfunction and vascular inflammation have emerged as additional ...
Fabrice Reyes   +7 more
wiley   +1 more source

Colchicine has Dose‐Dependent Therapeutic Effects in a LPS‐Induced Experimental Endotoxemia Model

open access: yesPharmacology Research & Perspectives
Colchicine is an ancient medication that has long been used for anti‐inflammatory properties. Because of unfavorable and toxic consequences of colchicine, selecting an appropriate dose is critical. The effects of three different doses (0.5, 1 or 5 mg/kg)
Meliksah Demir   +5 more
doaj   +1 more source

Adherence to colchicine treatment and colchicine resistance in a multicentric FMF national cohort [PDF]

open access: yes, 2020
Introduction: Colchicine is the standard treatment for Familiar Mediterranean Fever (FMF), however about 5% of patients (pts) experience colchicine resistance. There is no standard definition of colchicine resistance.
D. Rigante   +18 more
core  

Derivation of Mouse Dome‐Shaped Trophoblast Stem Cells With Low Heterogeneity From Blastocysts

open access: yesCell Proliferation, EarlyView.
Here, Liu et al. report the generation of mouse dome‐shaped trophoblast stem cells (dTSCs) with low heterogeneity and autonomous differentiation potential. dTSCs robustly generate all trophoblast lineages in vitro and contribute to the placenta in vivo, providing a refined model for studying trophoblast development and related disorders.
Minli Liu   +8 more
wiley   +1 more source

Colchicine-Related Polyneuropathy and Multiple Organ Failure

open access: yes, 2013
Colchicine arrests microtubule assembly and inhibits many cellular functions. This drug is used to treat gout and and Familial Mediterranean Fever. Its gastrointestinal side effects are frequent but more severe adverse effects such as neuropathy and ...
Turkel, Yakup, Dag, Ersel, Gokce, Burcu
core   +1 more source

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