Results 131 to 140 of about 16,654 (233)

Pharmacological Targets for Periodontitis: A Systematic Review of Drug‐Target Mendelian Randomisation Studies

open access: yesJournal of Periodontal Research, EarlyView.
This systematic review evaluated drug‐target Mendelian randomisation studies on periodontitis. Twelve studies identified host‐response‐related targets mainly involved in inflammatory, complement, and immune pathways. Although some targets were linked to existing drugs, the evidence remains preliminary and heterogeneous, requiring replication and ...
Luigi Nibali   +4 more
wiley   +1 more source

Effects of Antimitotic Agents, Temperature and Immersion Time on Chromosome Doubling Efficiency in Supersweet Corn (Zea mays L. var. saccharata)

open access: yesPlant Breeding, EarlyView.
ABSTRACT Doubled haploid technology accelerates the development of fully homozygous maize lines compared with conventional selfing. However, specific protocols for supersweet corn (Zea mays L. var. saccharata), particularly regarding immersion time in antimitotic solutions and temperature during chromosome doubling, remain poorly defined.
Vitor Joaquim de Lucena   +7 more
wiley   +1 more source

Improved Autotetraploid Induction Methods in Four Diploid Wild Peanut Species: Arachis duranensis, A. stenosperma, A. magna, and A. batizocoi

open access: yesPlant Breeding, EarlyView.
ABSTRACT Peanut (Arachis hypogaea L., 2n = 4x = 40, AABB) is an important legume crop worldwide. Wild peanuts (Arachis spp.) represent a valuable secondary gene pool with diverse disease resistances. However, most wild peanut species are diploid (2n = 2x = 20) and this ploidy barrier is a major obstacle to hybridization and gene introgression.
Chia‐Hung Shih   +4 more
wiley   +1 more source

An HPLC method for the quantification of colchicine and colchicine derivatives in gloriosa superba seeds

open access: yes, 2017
: An 80% ethanolic extract of Gloriosa superba L. seeds (glory lily, Colchicaceae), as well as a colchicine-poor/colchicoside-rich extract, were shown to exhibit antitumor activity in a murine model for pancreatic cancer.
Pieters, Luc   +3 more
core   +1 more source

Colchicine and pseudogout [PDF]

open access: yesArthritis & Rheumatism, 1982
T, González, M, Gantes
openaire   +2 more sources

Sustained Remission of Pediatric Bowel‐Associated Dermatosis‐Arthritis Syndrome With Risankizumab

open access: yesPediatric Dermatology, EarlyView.
ABSTRACT Bowel‐associated dermatosis‐arthritis syndrome (BADAS) is a rare neutrophilic dermatosis characterized by recurrent fever, arthralgias, and skin eruptions, most commonly occurring in patients with inflammatory bowel disease. We report the case of a 17‐year‐old female with Crohn's disease who developed BADAS and achieved complete and durable ...
Kylie E. Peake   +4 more
wiley   +1 more source

One day of environment‐induced heat stress causes injury to the murine kidney

open access: yesExperimental Physiology, EarlyView.
Abstract Environment‐induced heat stress (EIHS) results from sustained body temperature elevation owing to prolonged exposure to heat and humidity. We hypothesized that EIHS would cause kidney injury and cellular dysfunction. To test this hypothesis, female C57 mice were exposed to EIHS (n = 14; 37.6°C, 42.0% relative humidity) or thermoneutral (TN ...
Melissa Roths   +3 more
wiley   +1 more source

Giant cellulitis‐like Sweet's syndrome induced by gilteritinib

open access: yes
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Juan de Luque‐Fernández   +5 more
wiley   +1 more source

Mitophagy in skeletal muscle: Impact of ageing, exercise and disuse

open access: yesExperimental Physiology, EarlyView.
Abstract Skeletal muscle plays an important role in whole‐body health, quality of life and regulation of metabolism. The maintenance of a healthy mitochondrial pool is imperative for the preservation of skeletal muscle quality and is mediated through mitochondrial quality control consisting of mitochondrial turnover mediated by a balance between ...
Anastasiya Kuznyetsova, David A. Hood
wiley   +1 more source

TMEM16A Ca2+‐activated Cl− channel: Functional interactions with cytoskeletal and membrane‐associated proteins

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend The calcium‐activated chloride (ClCa) channel TMEM16A (also known as ANO1) plays critical roles in ion transport, neurotransmission and smooth muscle contraction. Dysregulation of TMEM16A channel activity contributes to the development and progression of various diseases.
Hisao Yamamura   +4 more
wiley   +1 more source

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