Results 61 to 70 of about 45,519 (269)

Endocan: A Novel Marker for Colchicine Resistance in Familial Mediterranean Fever Patients?

Frontiers in Pediatrics, 2021
Introduction: Familial Mediterranean fever (FMF) patients had 5–10% colchicine resistance. Although FMF attacks are characterized by acute phase elevation, there are no biomarkers that can show colchicine resistance yet.
Ahmet Omma, Berkan Armaǧan, Serdar Can Güven, Sevinç Can Sandıkçı, Seda Çolak, Çiǧdem Yücel, Orhan Küçükşahin, Abdulsamet Erden   +7 more
doaj   +1 more source

Perceptions about asymptomatic hyperuricemia and views about urate‐lowering therapy in people with asymptomatic hyperuricemia

Arthritis Care &Research, Accepted Article.
Background/Aims Asymptomatic hyperuricemia is a precursor of gout and is also associated with cardiovascular disease and chronic kidney disease. The aim of this study was to understand perceptions about asymptomatic hyperuricemia and views about urate‐lowering therapy in people with asymptomatic hyperuricemia.
Nicola Dalbeth, Sarah Stewart, Gregory D Gamble, Borislav Mihov, Lisa K Stamp, Janine Haslett, William J Taylor, Tony R Merriman, Adwoa Dansoa Tabi‐Amponsah, Anne Horne, Tuhina Neogi, Tristan Pascart, Mariano Andrés, Maria‐Luisa Peral‐Garrido, Eleonora Norkuviene, Janitzia Vazquez Mellado, Till Uhlig, Mingshu Sun, Changgui Li, Keith J Petrie   +19 more
wiley   +1 more source

Effectiveness of colchicine among patients with COVID-19 infection: A randomized, open-labeled, clinical trial

Indian Journal of Rheumatology, 2022
Background and Objective: In November 2019, there were abundant cases of COVID-19 which first case was reported in Wuhan, China. Colchicine has an important role in inhibiting activation of NLRP3 inflammasome that predispose to decrease cytokine ...
Aryan Mohamadfatih Jalal, Sheelan Faroz Aref, Dashty Abbas Albustany   +2 more
doaj   +1 more source

Colchicine [PDF]

, 2019
Colchicine is an alkaloid which was originally extracted from bulbs of a plant called Colchicum autumnale (meadow saffron). Its active pharmacological component was isolated in 1820 and in 1833 the active ingredient was purified and named colchicine. It consists of three hexameric rings termed A, B, and C.
openaire   +1 more source

Colchicine Attenuates Inflammation Beyond the Inflammasome in Chronic Coronary Artery Disease: A LoDoCo2 Proteomic Substudy.

Circulation, 2020
Inflammation has a crucial role in the progression of atherosclerosis. COLCOT (Colchicine Cardiovascular Outcome Trial) recently showed cardiovascular benefit of treatment with colchicine.1 Colchicine is an established anti-inflammatory drug, which ...
T. Opstal, Renate M. Hoogeveen, A. Fiolet, M. Silvis, Salem H K The, W. Bax, D. D. de Kleijn, A. Mosterd, E. Stroes, J. Cornel   +9 more
semanticscholar   +1 more source

Effect of Colchicine vs Usual Care Alone on Intubation and 28-Day Mortality in Patients Hospitalized With COVID-19

JAMA Network Open, 2021
Key Points Question Does colchicine prevent intubation and mortality in hospitalized patients with COVID-19 pneumonia? Findings In this randomized clinical trial of 1279 patients hospitalized with COVID-19, patients allocated to receive colchicine plus ...
R. Diaz, A. Orlandini, N. Castellana, A. Caccavo, P. Corral, G. Corral, C. Chacón, P. Lamelas, F. Botto, M. Díaz, J. M. Domínguez, A. Pascual, Carla Rovito, Agustina Galatte, Franco Scarafia, O. Sued, Omar Gutierrez, S. Jolly, J. Miró, J. Eikelboom, M. Loeb, A. Maggioni, Deepak L. Bhatt, S. Yusuf   +23 more
semanticscholar   +1 more source

Exploring patients’ profiles associated with the resolution of acute calcium pyrophosphate arthritis treatedwith colchicine and prednisone: post hoc analysis of a randomized controlled trial

Arthritis Care &Research, Accepted Article.
Objective The objective was to identify factors determining acute arthritis resolution and safety with colchicine and prednisone in acute calcium pyrophosphate (CPP) crystal arthritis. Methods We conducted a post hoc analysis of the COLCHICORT trial, which compared colchicine and prednisone for the treatment of acute CPP crystal arthritis, using a ...
Tristan Pascart, Laurène Norberciak, Pascal Richette, Pierre Robinet, Aurore Pacaud, Gauthier Marchasson, Thibault Rabin, Hélène Luraschi, Pierre Maciejasz, Anne‐France Georgel, Augustin Latourte, Hang‐Korng Ea, Sébastien Ottaviani, Charlotte Jauffret, Vincent Ducoulombier   +14 more
wiley   +1 more source

Identification of Pycnoporus coccineus KKUPN1 and Effect of Colchicine Treatment on Growth and Enzyme Production

Journal of Pure and Applied Microbiology, 2017
The objective of this study was to identify and study the effect of colchicine treatment on the growth and enzyme production of Pycnoporus coccineus KKUPN1.
W. Sutthisa1 , Sanoamuang2,3
doaj   +1 more source

Oxygen Saturation in Hospitalized COVID-19 Patients and Its Relation to Colchicine Treatment: A Retrospective Cohort Study with an Updated Systematic Review

Medicina, 2023
Background: Colchicine has been proposed as a cytokine storm-blocking agent for COVID-19 due to its efficacy as an anti-inflammatory drug. The findings of the studies were contentious on the role of colchicine in preventing deterioration in COVID-19 ...
Sandy Sharaf, Rasha Ashmawy, Eman Saleh, Mayada Salama, Yousra A. El-Maradny, Ali Zari, Shahinda Aly, Ahmed Tolba, Doaa Mahrous, Hanan Elsayed, Dalia Latif, Elrashdy M. Redwan, Ehab Kamal   +12 more
doaj   +1 more source

Anti‐inflammatory mechanisms and research progress of colchicine in atherosclerotic therapy

Journal of Cellular and Molecular Medicine, 2021
Inflammatory responses play a vital role in the onset and development of atherosclerosis, and throughout the entire process of the chronic disease.
Yuyu Li, Yu-xin Zhang, Jianrong Lu, Yong Yin, Jun Xie, Biao Xu   +5 more
semanticscholar   +1 more source