Results 81 to 90 of about 77,446 (306)
Clonal Hematopoiesis and Thrombosis
American Journal of Hematology, EarlyView.ABSTRACT Clonal hematopoiesis (CH) has been the focus of many research efforts in the last years and has emerged as a risk modifier for cardiovascular disease morbidity and mortality. While substantial evidence has accumulated regarding its impact on arterial system diseases, the connection with venous thrombosis has only recently been explored.
Cornelia Englisch, Cihan Ay
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Journal of Food Biochemistry, Volume 46, Issue 12, December 2022., 2022 Breast cancer (BC) is one of the most challenging cancers to treat. Nutraceuticals acting by attenuating Hedgehog, NF‐κB, and Wnt/β‐catenin pathways. Nutraceuticals have medical characteristics and may cure cancer Abstract Breast cancer (BC) is one of the most challenging cancers to treat, accounting for many cancer‐related deaths.
Khalid Saad Alharbi +11 more
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Colchicine did not affect the viability of induced 2n pollen in Populus tomentosa
Silva Fennica, 2019 Colchicine is widely used as a mutagen to induce production of diploid gametes in plants. However, whether colchicine affects induced pollen viability remains unclear.
Yan Liu +4 more
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, 2019 Colchicine is an alkaloid which was originally extracted from bulbs of a plant called Colchicum autumnale (meadow saffron). Its active pharmacological component was isolated in 1820 and in 1833 the active ingredient was purified and named colchicine. It consists of three hexameric rings termed A, B, and C.
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JACC: Case Reports, 2020 Colchicine toxicity results in fatal multiorgan failure. We present a case of colchicine toxicity resulting in transient biventricular failure and cardiogenic shock that were successfully treated with packed red blood cell exchange. (Level of Difficulty: Beginner.)
Steven E. Reis +7 more
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Animal Models and Experimental Medicine, EarlyView.KLF4 (Krüppel‐like factor 4) plays a protective role in blood–brain barrier (BBB). KLF4 plays an ambiguous role in the central nervous system. KLF4 in the BBB endothelial cells could be a potential target for Alzheimer's disease. Abstract Alzheimer's disease is the most prevalent chronic neurodegenerative disorder worldwide, with no sufficient cure ...
Ziying Wei +4 more
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Systemic lupus erythematosus and cardiovascular disease
Journal of Internal Medicine, Volume 293, Issue 1, Page 48-62, January 2023., 2023 Abstract The prognosis in systemic lupus erythematosus (SLE) has improved due to better treatment and care, but cardiovascular disease (CVD) still remains an important clinical problem, since the risk of CVD in SLE is much higher than among controls.
Johan Frostegård
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Oxidative Medicine and Cellular Longevity, 2020 Cholesterol crystal- (CC-) induced endothelial cell inflammation and pyroptosis play an important role in the development of cardiovascular diseases, especially in atherosclerosis (AS).
Mengyue Yang +12 more
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Arthritis &Rheumatology, Accepted Article.Objectives This study aims to assess the risk of non‐infectious uveitis (NIU) relapse in pediatric patients undergoing Adalimumab (ADA) tapering, evaluating potential predictors of such risk Methods We conducted a multicenter retrospective cohort study involving pediatric NIU patients who underwent ADA tapering due to inactive uveitis. Cox proportional
Achille Marino +31 more
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Mediators of Inflammation, 2020 Objective. To analyze the potential role of colchicine monotherapy in patients with tumor necrosis factor receptor associated periodic syndrome (TRAPS) in terms of control of clinical and laboratory manifestations. Methods.
Antonio Vitale +23 more
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