Results 21 to 30 of about 1,972,874 (316)

MECP2 regulates cortical plasticity underlying a learned behaviour in adult female mice

open access: yesNature Communications, 2017
Rett syndrome is associated with impaired synaptic connectivity beginning in early development. Here the authors show in female mice heterozygous forMecp2, a model of Rett syndrome, that during adulthood, auditory cortex plasticity associated with a ...
Keerthi Krishnan   +4 more
doaj   +1 more source

Neural Networks With Motivation

open access: yesFrontiers in Systems Neuroscience, 2021
Animals rely on internal motivational states to make decisions. The role of motivational salience in decision making is in early stages of mathematical understanding.
Sergey A. Shuvaev   +5 more
doaj   +1 more source

Trafficking and localization of KNOTTED1 related mRNAs in shoot meristems

open access: yesCommunicative & Integrative Biology, 2022
Multicellular organisms use transcripts and proteins as signaling molecules for cell-to-cell communication. Maize KNOTTED1 (KN1) was the first homeodomain transcription factor identified in plants, and functions in maintaining shoot stem cells.
Munenori Kitagawa   +2 more
doaj   +1 more source

Effectiveness of Cold Compress and Lavender Aromatherapy on Reduction in Postpartum Perineal Pain Intensity [PDF]

open access: yes, 2020
Introduction: Every postpartum mother got a perineal wound and experience pain. This pain results in unpleasant effect such as fear of movement which can lead to problems such as sub uterine involution, unhealthy release of lochea, and postpartum ...
Qomariah, Siti Nur   +3 more
core   +1 more source

Multi-color Flow Cytometry for Comprehensive Analysis of the Tumor Immune Infiltrate in a Murine Model of Breast Cancer

open access: yesBio-Protocol, 2021
Flow cytometry is a popular laser-based technology that allows the phenotypic and functional characterization of individual cells in a high-throughput manner.
Ana Almeida, Miriam Fein, Mikala Egeblad
doaj   +1 more source

Fatigue life improvement in fatigue-aged fastener holes using the cold expansion technique [PDF]

open access: yes, 2003
The use of cold expansion process as a life extension technique on aircraft structural joints was investigated. The primary focus was an experimental test programme consisting of open-hole and low-load transfer joint specimens made of 2024-T351 ...
Wang, Z., Zhang, Xiang
core   +1 more source

P53 Mutations Change Phosphatidylinositol Acyl Chain Composition

open access: yesCell Reports, 2015
Phosphatidylinositol phosphate (PIP) second messengers relay extracellular growth cues through the phosphorylation status of the inositol sugar, a signal transduction system that is deregulated in cancer.
Adam Naguib   +9 more
doaj   +1 more source

PTPN23-dependent ESCRT machinery functions as a cell death checkpoint

open access: yesNature Communications
Cell death plasticity is crucial for modulating tissue homeostasis and immune responses, but our understanding of the molecular components that regulate cell death pathways to determine cell fate remains limited.
Dongyan Song   +10 more
doaj   +1 more source

Sex-Specific Stress-Related Behavioral Phenotypes and Central Amygdala Dysfunction in a Mouse Model of 16p11.2 Microdeletion

open access: yesBiological Psychiatry Global Open Science, 2021
Background: Substantial evidence indicates that a microdeletion on human chromosome 16p11.2 is linked to neurodevelopmental disorders, including autism spectrum disorder (ASD).
Jacqueline Giovanniello   +3 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

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