Results 81 to 90 of about 2,154,939 (308)
Supporting Integrated and Comprehensive Approaches to Climate Change Adaptation in Africa [PDF]
, 2010 The Africa Adaptation Programme (AAP) has been designed to support the long-term efforts of targeted countries to further develop their capability to successfully identify, design and implement holistic adaptation and disaster risk reduction programmes ...
The Africa Adaptation Programme (AAP)
core
Glaciers and Ice Sheets As Analog Environments of Potentially Habitable Icy Worlds
Frontiers in Microbiology, 2017 Icy worlds in the solar system and beyond have attracted a remarkable attention as possible habitats for life. The current consideration about whether life exists beyond Earth is based on our knowledge of life in terrestrial cold environments.
Eva Garcia-Lopez, Cristina Cid
doaj +1 more source
Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells
FEBS Open Bio, EarlyView.Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla +10 more
wiley +1 more source
, 2016 Metabolic flexibility is an important component of adaptation to stressful environments, including thermal stress and latitudinal adaptation. A long history of population genetic studies suggest that selection on core metabolic enzymes may shape life ...
David B. Allison (49148) +6 more
core +1 more source
The nature of human adaptation to cold
, 2002 Human adaptation to repeated short term exposure to cold appears to be characterised by a decreased shivering threshold and unchanged sweating threshold, producing a widening of the inter-threshold zone (1).
Clare Eglin (7152989) +5 more
core +1 more source
ERECTA genes and their ligands regulate shoot and inflorescence architecture in maize
Nature CommunicationsIn maize, several yield-related traits are associated with meristem activity, regulated by CLAVATA3/EMBRYO SURROUNDING REGION-related (CLE) peptide signals perceived by CLAVATA(CLV) receptors in the CLAVATA-WUSCHEL (CLV-WUS) pathway.
Xiao Liu +14 more
doaj +1 more source
Plant adaptation to cold climates [PDF]
F1000Research, 2016 In this short review, I will first summarize criteria by which environments can be considered “cold”, with plant stature (size, height above ground) playing a central role for the climate actually experienced. Plants adapted to such environments have to cope with both extremes and with gradual influences of low temperature.
openaire +3 more sources
In vitro generation of regulatory T cells: A challenging tool for studying immune aging in humans
FEBS Open Bio, EarlyView.In vitro induction of human regulatory T cells using standard protocols generates suppressive, Foxp3‐expressing CD4+ T cells independently of TGF‐β supplementation and donor age. Regulatory T (Treg) cells play a key role in immune tolerance and homeostasis.
Lynn Muller +3 more
wiley +1 more source
The Effects of Cold Adaptation on the Growth and Development of the Neandertal Cranial Base [PDF]
, 2014 Neandertals and modern humans possess very different craniofacial shapes. Some recent work has attributed these contrasting shapes specifically to differences in brain development, which are extrapolated to mean differences in cognitive function. However,
Caldwell, Sarah
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FEBS Open Bio, EarlyView.The PAM pathway and its impact on cellular metabolism. Color‐coded key symbols represent Rapamycin (R, orange, targeting mTOR) and Dactolisib (D, green, targeting PI3K/mTOR), indicating their sites of action. Created with BioRenders.com. Glioblastoma resists therapy through interconnected survival programs.
Kai Zhao +23 more
wiley +1 more source