Results 71 to 80 of about 158,908 (304)

ERECTA genes and their ligands regulate shoot and inflorescence architecture in maize

Nature Communications
In maize, several yield-related traits are associated with meristem activity, regulated by CLAVATA3/EMBRYO SURROUNDING REGION-related (CLE) peptide signals perceived by CLAVATA(CLV) receptors in the CLAVATA-WUSCHEL (CLV-WUS) pathway.
Xiao Liu, Jinbiao Wang, Jipeng Li, Lu Kang, Mengyan Wang, Zhaoyu Huang, Jarrett Man, Xuxu Huang, Zhiming Zhang, Fang Yang, Madelaine Bartlett, Liuji Wu, Zhaobin Dong, David Jackson, Fang Xu   +14 more
doaj   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Cold Shock as a Screen for Genes Involved in Cold Acclimatization in Neurospora crassa

G3: Genes, Genomes, Genetics, 2018
When subjected to rapid drops of temperature (cold shock), Neurospora responds with a temporary shift in its morphology. This report is the first to examine this response genetically.
Michael K. Watters, Victor Manzanilla, Holly Howell, Alexander Mehreteab, Erik Rose, Nicole Walters, Nicholas Seitz, Jacob Nava, Sienna Kekelik, Laura Knuth, Brianna Scivinsky   +10 more
doaj   +1 more source

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

FEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao, Daiki Kobayashi, Shogo Hori, Osamu Saitoh   +3 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Searching for signatures of cold adaptation in the Neanderthal and Denisovan genomes: hints from the brown adipose tissue genes

, 2012
Neandertal and Denisovan clades of archaic hominins experienced temperatures significantly lower than the present ones, occupying geographical regions involved in the Pleni-Wurm for a time interval long enough to adapt to this cold environment ...
SAZZINI, MARCO, DE FANTI, SARA, CASADIO, RITA, Schiavo G., LUISELLI, DONATA, MARTELLI, PIER LUIGI   +5 more
core  

Widely Targeted Metabolomics and Transcriptomics Analysis of the Response and Adaptation Mechanisms of Trifolium ambiguum to Low-Temperature Stress

Agronomy
Caucasian clover (Trifolium ambiguum M.Bieb.) is a perennial legume known for its exceptional cold tolerance, commonly used in agriculture and ecosystems in cold climates.
Kefan Cao, Sijing Wang, Huimin Zhang, Yiming Ma, Qian Wu, Mingjiu Wang   +5 more
doaj   +1 more source

Comparative analysis of membrane lipids in psychrophilic and mesophilic freshwater dinoflagellates

Frontiers in Plant Science, 2016
Here we report the lipid profiles of ten dinoflagellate species originating from different freshwater habitats and grown at 4, 13 or 20°C akin to their natural occurrence.
Andrea eAnesi, Ulrike eObertegger, Gert eHansen, Assaf eSukenik, Giovanna eFlaim, Graziano eGuella, Graziano eGuella   +6 more
doaj   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Data from: Cold adaptation increases rates of nutrient flow and metabolic plasticity during cold exposure in Drosophila melanogaster [PDF]

, 2016
Metabolic flexibility is an important component of adaptation to stressful environments, including thermal stress and latitudinal adaptation. A long history of population genetic studies suggest that selection on core metabolic enzymes may shape life ...
Morgan, Theodore J., Sunny, Nishanth E, Allison, David B, Allison, David, Hahn, Daniel A, Allison, David B., Szejner-Sigal, Andre, Sunny, Nishanth E., McCue, Marshall D, Williams, Caroline M., Hahn, Daniel, McCue, Marshall D., Morgan, Theodore, Hahn, Daniel A., Williams, Caroline M, Morgan, Theodore J   +15 more
core   +1 more source