Results 61 to 70 of about 2,026,673 (304)

Framing adaptation in the Victorian context: synthesis report [PDF]

open access: yes, 2013
This synthesis report provides a summary of the research activity and conveys the key findings arising from the 18 month ‘Framing Adaptation in the Victorian Context’ project undertaken between 2010 and 2012.
Hartmut Funfgeld, Darryn McEvoy
core  

Aii810, a Novel Cold-Adapted N-Acylhomoserine Lactonase Discovered in a Metagenome, Can Strongly Attenuate Pseudomonas aeruginosa Virulence Factors and Biofilm Formation

open access: yesFrontiers in Microbiology, 2017
The pathogen Pseudomonas aeruginosa uses quorum sensing (QS) to control virulence and biofilm formation. Enzymatic disruption of quorum sensing is a promising anti-infection therapeutic strategy that does not rely on antibiotics.
Xinjiong Fan   +5 more
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Valuing adaptation under rapid change [PDF]

open access: yes, 2013
The methods used to plan adaptation to climate change have been heavily influenced by scientific narratives of gradual change and economic narratives of marginal adjustments to that change.
Celeste Young   +2 more
core  

Untargeted metabolomics reveals key steroidal glycoalkaloids and associated metabolites in crude and C18-purified extracts of potato leaves

open access: yesBMC Plant Biology
Background Potato leaves are an abundant by-product of potato production. Although they contain steroidal glycoalkaloids (SGAs) and other bioactive metabolites, the chemical composition of SGA-enriched leaf extracts and the impact of purification steps ...
Yuru Lv   +9 more
doaj   +1 more source

Effect of Low Temperature on Content of Primary Metabolites in Two Wheat Genotypes Differing in Cold Tolerance

open access: yesMetabolites
The study of cold-tolerance mechanisms of wheat as a leading cereal crop is very relevant to science. Primary metabolites play an important role in the formation of increased cold tolerance. The aim of this research is to define changes in the content of
Alexander Deryabin   +3 more
doaj   +1 more source

Forming of adaptation of students' organism to the cold factor by the methods of active conditioning to the cold in the process of physical education in the institute of higher [PDF]

open access: yesPedagogìka, Psihologìâ ta Mediko-bìologìčnì Problemi Fìzičnogo Vihovannâ ì Sportu, 2012
A research purpose was a ground of the system forming of adaptation to the cold of organism of students which master speciality the "Cryogenic technique and technologies». 25 students of the first course took part in research.
Khalaydzhi S.V.
doaj   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

Supporting evidence-based adaptation decision-making in the Australian Capital Territory: a synthesis of climate change adaptation research [PDF]

open access: yes, 2013
This research synthesis provides policy-makers and practitioners with an understanding of the building blocks for effective adaptation decision-making, as evidenced through the NCCARF research program.
Jennifer Cane
core  

Structure and function of hemoproteins from cold-adapted organism [PDF]

open access: yes, 2011
Environmental oxygen availability certainly plays a key role in the evolution of polar marine life, as suggested by the physiological and biochemical strategies that the organisms have adopted to acquire, deliver and scavenge oxygen.
Russo, Roberta
core   +1 more source

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