Results 41 to 50 of about 158,908 (304)
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Molecular basis of cold adaptation [PDF]
, 2002 peer reviewedCold-adapted, or psychrophilic, organisms are able to thrive at low temperatures in permanently cold environments, which in fact characterize the greatest proportion of our planet.
Georlette, D. +8 more
core +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Climate change adaptation in the boardroom [PDF]
, 2013 Climate adaptation is recognised by many of the world’s largest businesses as a global risk and one that requires critical attention. The World Economic Forum’s 2013 Global Risks Perception Survey, identified the ‘failure of climate change adaptation and
Mark Baker-Jones +2 more
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Experimental Biology and Medicine, 1963 SummaryRats exposed to cold (6°C) for one month show a very rapid and sustained increase in urinary histamine. At the end of this period animals develop a certain tolerance to histamine aerosols. This modification in histamine excretion in the cold possibly reflects mast cell changes and the decreased sensitivity to this amine in cold adapted animals ...
openaire +2 more sources
A Cold Limit to Adaptation in the Sea [PDF]
Trends in Ecology & Evolution, 2016 Temperature affects biological functions by altering reaction rates. Physiological rates usually double to treble for every 10 °C rise, and 1-4 fold encompasses normal biological functions. However, in polar marine species inhabiting temperatures around 0 °C many processes are slowed beyond the Arrhenius relationships for warmer water species.
openaire +3 more sources
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Ecological IndicatorsIn recent decades, alpine meadows have experienced severe degradation owing to external disturbances. Although soil microorganisms are critical for ecosystem services, little is known about their responses to soil degradation and the potential patterns ...
Yu Sun +9 more
doaj +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Joining the dots: hydrology, freshwater ecosystem values and adaptation options [PDF]
, 2013 The objective of this research was to investigate and test the necessary steps in developing an adaptation planning framework for freshwater biodiversity.
Leon Barmuta, Peter Davies, Anne Watson
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