Results 1 to 10 of about 4,070 (143)

Exacerbation of asthma and neutrophil-dominated airway inflammation in patients with cold-induced airway hyperresponsiveness

Бюллетень сибирской медицины, 2021
Background. Neutrophils can play a significant role in the formation of bronchial inflammation in asthma  exacerbation in patients with cold-induced airway hyperresponsiveness (CIAHR).Aim.
A. B. Pirogov, A. G. Prikhodko, E. Yu. Afanaseva, E. G. Sheludko, Ya. G. Gorchakova, X. Zhou, Q. Li, Yu. M. Perelman   +7 more
doaj   +3 more sources

Efficiency of using a short-acting β2-agonist for the relief of acute cold bronchospasm in asthma patients with cold airway hyperresponsiveness

Сибирский научный медицинский журнал, 2022
Excessive sensitivity of the respiratory tract to physical and chemical environmental triggers can vary for many reasons, reducing the therapy effectiveness in a patient with asthma. Aim of the study was to investigate the effectiveness of a short-acting
A. G. Prihodko, J. M. Perelman
doaj   +2 more sources

Content of Th17 related and Th2 cytokines in asthma patients with cold airway hyperresponsiveness

Медицинская иммунология
The phenomenon of cold airway hyperresponsiveness is rather common among patients with bronchial asthma. Possible participation of immune mechanisms in its occurence is scarcely studied.
A. B. Pirogov, A. G. Prikhodko, N. A. Pirogova, D. E. Naumov, D. A. Gassan, J. M. Perelman   +5 more
doaj   +2 more sources

Clinical and pathogenetic aspects of neutrophilic bronchial inflammation in asthma patients with cold-induced airway hyperresponsiveness (literature review)

Бюллетень сибирской медицины, 2023
The review presents data on the effect of neutrophilic bronchial inflammation on the clinical course, external respiration, and formation of the airway response to cold air in patients with asthma.
A. B. Pirogov, A. G. Prikhodko, N. A. Pirogova, J. M. Perelman   +3 more
doaj   +2 more sources

Destruction of the bronchial epithelium in patients with severe asthma according to different patterns of inflammation and cold airway hyperresponsiveness [PDF]

Терапевтический архив, 2019
The aim of the research was to study the state of the bronchial mucosa epi-thelium in relation to the severity of clinical manifestations in severe uncon-trolled asthma depending on the pattern of inflammation and the presence of cold airway ...
A B Pirogov, D A Gassan, S S Zinov’ev, A G Prikhodko, V P Kolosov, J M Perelman   +5 more
doaj   +4 more sources

Interleukin-4 and interferon gamma in bronchial remodeling in asthma patients with cold airway hyperresponsiveness

Бюллетень сибирской медицины
Interleukin-4 (IL-4) and interferon gamma (IFNγ) are key participants in the polarization of the immune response toward Th1 or Th2 types in bronchial asthma.
A. B. Pirogov, A. G. Prikhodko, N. A. Pirogova, D. A. Gassan, D. E. Naumov, J. M. Perelman   +5 more
doaj   +2 more sources

Seasonal dynamics of cold airway hyperresponsiveness in patients with asthma

Bulletin Physiology and Pathology of Respiration, 2021
Introduction. Cold air-induced bronchoconstriction in patients with asthma, leading to a breakdown in disease control, is one of the most serious problems in the northern countries of the world.Aim. To assess the seasonal dynamics of the airway response (ΔFEV1CA) to cold bronchoprovocation in asthma patients with cold airway hyperresponsiveness (CAHR ...
A. G. Prikhodko, J. M. Perelman
openaire   +2 more sources

Bronchial granulocytes in the development of epithelial destruction and oxidative lipid modification in patients with bronchial asthma with cold and osmotic airway hyperresponsiveness

Сибирский научный медицинский журнал, 2021
Free radical damage to the respiratory tract in patients with asthma leads to the destruction of the bronchial parenchyma and the generation of signaling molecules of inflammation by parenchymal cells.
A. B. Pirogov, A. G. Prikhodko, Ju. M. Perelman   +2 more
doaj   +1 more source

Sputum cellular profile and myeloperoxidase activity in asthma patients with cold airway hyperresponsiveness

Siberian Medical Review, 2022
Th e aim of the research. To study the infl ammation pattern, myeloperoxidase activity and the content of the epithelium in the bronchi of patients with bronchial asthma (BA) with diff erent forms of airway hyperresponsiveness to physical stimuli. Material and methods.
A.B. Pirogov, A.G. Prikhodko, J.M. Perelman   +2 more
openaire   +1 more source

Cinnamomum cassia (L.) J.Presl Alleviates Allergic Responses in Asthmatic Mice via Suppression of MAPKs and MMP-9

Frontiers in Pharmacology, 2022
The prevalence of asthma is gradually increasing, and endangers human health. Many therapeutic agents have been developed to address this concern. Cinnamomum cassia (L.) J.Presl is a traditional herbal remedy in China, Japan, and Korea and used mainly to
Je-Oh Lim, Yun Hee Kim, Ik Soo Lee, Woong-Il Kim, Se-Jin Lee, So-Won Pak, In-Sik Shin, Taesoo Kim   +7 more
doaj   +1 more source