Results 91 to 100 of about 13,457 (260)

The effect of Cold Plasma (Combined Argon/Helium Gases) on Microbial Contamination and Physicochemical Properties of Minced Sheep Meat

Journal of Medical Microbiology and Infectious Diseases, 2019
Introduction: The demand for consuming healthy food has increased due to the developed techniques for assessing food safety and detection of microbial contamination.
Farideh Pidaei, Anoosheh Sharifan, Ramona Masoud   +2 more
doaj  

Ultra‐Radiostable Covalent Conformationally Interlocked Networks Enabling a Universal Radiometal‐Labeling Platform for Cancer Radioembolization

Advanced Science, EarlyView.
Conjugated poly(imide dioxime)‐based microspheres establish a radiometal coordination‐driven conformational interlocked network with ultra‐high radiostability. This platform enables low‐temperature, multi‐radionuclide labeling for SPECT/PET/MRI imaging and radionuclide therapy. Mechanistic insights from EXAFS and DFT reveal enhanced stability, while in
Xiao Xu, Zhenwen Zhao, Yangjie Wang, Zhigang Liu, Zhijie Liu, Xiaoling Li, Zhichen Mao, Lu Xu, Gan Lin, Gang Liu, Hongjuan Ma   +10 more
wiley   +1 more source

On Hemostasis of Cold Atmospheric Air Plasma

Open Journal of Emergency Medicine, 2018
The efficacy and mechanism of a cold atmospheric-pressure air plasma (CAAP), which carries abundant atomic oxygen (OI), on blood coagulation are studied. The tests on sodium citrate mixed blood-droplet samples show that 1) The heat delivered by the CAAP has no impact on the observed clot formation, 2) Plasma effluent activates platelets to promote ...
openaire   +2 more sources

Ultrasound‐Recharged Sub‐Nanometer Palladium Catalysts for on‐Demand and Self‐Terminating Bioorthogonal Prodrug Activation in Cancer Therapy

Advanced Science, EarlyView.
Safe and precise bioorthogonal therapy of tumors was achieved by an ultrasound‐responsive heterostructured nanoreactor with on‐demand catalytic activity. Under piezoelectric catalysis, the system undergoes reversible Pd2+/Pd0 redox cycling, concurrently enabling spatiotemporally controlled prodrug activation and self‐terminating catalytic dose ...
Daqing Xia, Lei Liu, Shuang Jin, Guangxu Fang, Chang Yu, Yunyun Wu, Lunli Xiang, Hongrui Zhu, Zhenqiang Wang, Jixi Zhang   +9 more
wiley   +1 more source

EpCAM+ Extracellular Vesicle PD‐L1 Dynamics as a Predictive Biomarker of Immune Checkpoint Blockade Response

Advanced Science, EarlyView.
A highly sensitive SERS‐based platform measures PD‐L1 expression on EpCAM+ circulating EVs from cancer patients undergoing immunotherapy. Monitoring dynamic changes after treatment reveals that reduced EpCAM+ EV PD‐L1 levels associate with improved long‐term clinical outcomes, establishing a non‐invasive approach for tracking immune checkpoint ...
Byeonggeol Mun, Jinyoung Kim, Chang Gon Kim, Seokhyeong Go, Mina Han, Yujin Ouck, Soojin Jang, Seong Uk Son, Gamin Kim, Wonrak Son, Eunjung Kim, Min Hee Hong, Ja Hyun Yeo, Eun‐Kyung Lim, Hye Ryun Kim, Seungjoo Haam   +15 more
wiley   +1 more source

Chemically Gradient Ordered Nanodomains Enable Large Tensile Ductility in Gigapascal Lightweight Refractory High‐Entropy Alloys

Advanced Science, EarlyView.
A high‐strength lightweight refractory high‐entropy alloy achieves extraordinary ductility owing to the introduction of coherent chemically gradient ordered nanodomains (CGONs). The CGONs not only serve as effective barriers to dislocation motion (strengthening) but also significantly promote dislocation nucleation and multiplication (ductilizing) upon
Wei Zhang, Dingshun Yan, Yong Zhang, Zhiming Li   +3 more
wiley   +1 more source

Penfluridol Triggers GSDME‐Mediated Immunogenic Pyroptosis to Potentiate Antitumor Immunotherapy

Advanced Science, EarlyView.
A high‐throughput screen of FDA‐approved antipsychotics identifies penfluridol as a potent pyroptosis inducer acting via direct TTI1 inhibition. This triggers TNFA‐NFKB signaling and caspase‐8/‐3‐dependent GSDME cleavage. The compound stimulates antitumor immunity alone and synergizes with anti‐PD‐1 therapy, while low TTI1 expression emerges as a ...
Linfeng Li, Daishi Li, Danyao Chen, Yating Dian, Lei Yao, Hui Su, Ziyu Guo, Deze Zhao, Zihua Wu, Furong Zeng, Chunfang Zhang, Guangtong Deng   +11 more
wiley   +1 more source

Label‐Free Myelin Fingerprinting: An Adult Human Post‐Mortem Brain Slice Platform via Coherent Anti‐Stokes Raman Spectroscopy

Advanced Science, EarlyView.
A serum‐free, air–liquid interface organotypic slice culture model preserves human post‐mortem corpus callosum tissue, successfully recovering from slicing trauma to reflect the donor's underlying disease state. Pairing label‐free Coherent anti‐Stokes Raman scattering (CARS) microscopy with k‐means clustering enables objective, high‐resolution ...
Kasra Roya‐Kouchaki, Jeroen P. Korterik, Femke Tjebbes, Geert J. Schenk, Herman L. Offerhaus, Antonio Luchicchi   +5 more
wiley   +1 more source

The application of cold atmospheric plasma technology in the brain: The potential role of reactive species in neuroprotection effects of plasma

مجله دانشگاه علوم پزشکی بیرجند
Reactive oxygen species (ROS) and reactive nitrogen species (RNS) play crucial roles as signaling molecules in neurophysiology. While high levels of ROS and RNS can lead to neuronal damage, their low levels stimulate growth and development and suggest ...
Yasaman Firouzjaei, Akbar Hajizadeh Moghaddam, Sedigheh Khanjani Jolodar, Farshad Sohabatzadeh   +3 more
doaj  

Optimized Antimony‐Doped Tin Oxide Thin Films With Enhanced Electrical Properties for Low‐Emissivity Architectural Coatings

Advanced Science, EarlyView.
Antimony‐doped tin oxide (ATO) thin films were deposited by aerosol‐assisted chemical vapor deposition (AACVD) and systematically investigated to establish correlations between Sb doping level, structural properties and optoelectronic performance. Optimized films exhibited low sheet resistance, high carrier concentrations, and high visible transparency
Iqra Ramzan, Ivan P. Parkin, Claire J. Carmalt   +2 more
wiley   +1 more source