Results 81 to 90 of about 2,711,276 (289)
Advanced Science, EarlyView.ABSTRACT Astrocyte reactivity critically shapes neuroinflammatory outcomes after ischemic stroke, yet the upstream regulators governing astrocyte state transitions remain incompletely defined. Here, we identify the immunoproteasome subunit low molecular weight protein 2 (LMP2) as an important modulator of astrocyte functional remodeling following ...
Yanguang Mao +7 more
wiley +1 more source
Advanced Science, EarlyView.An optimized ex vivo human liver slice culture system preserves tissue architecture, hepatocyte function, and immune‐stromal complexity for at least five days. By refining slice thickness, oxygenation, air‐liquid interface, and extracellular matrix support, the platform enables human‐relevant hepatotoxicity testing and mechanistic studies, offering a ...
Huiche Feng +17 more
wiley +1 more source
Atmospheric Plasma and Prostate Cancer [PDF]
Translational Research in UrologyPlasma semi-ionized gas is a novel tool with various applications, from engineering to medicine. In light of improved plasma devices and the invention of cold plasma at room temperature in recent years, plasma medicine has gained much attention from ...
Setareh Zahedian
doaj +1 more source
Cold Atmospheric Plasma (CAP) In Dentistry [PDF]
Dentistry, 2013 This review article on plasma therapy in dentistry is intended to provide with a summary of the current status of this emerging field, its scope, and its broad interdisciplinary approach. Matter usually includes liquids, solids, and gases. But a fourth category of matter has been discovered called plasma that's actually the most unusual and the most ...
openaire +1 more source
Advanced Science, EarlyView.By overcoming the fixed‐path limitations of conventional machine learning, a heterogeneous graph neural network fundamentally reconstructs material data representation. Integrating variable processing sequences with intrinsic elemental features, this framework enables exploratory optimization across high‐dimensional spaces.
Jie Yin +12 more
wiley +1 more source
Advanced Science, EarlyView.This study presents a surfaceome‐reprogramming strategy for mutation‐independent lung cancer therapy by repurposing dexamethasone to prime mesenchymal stem cell‐derived nanovesicles. The engineered vesicles leverage multi‐valent interactions mediated by upregulated adhesion proteins, EPHA2, and NOTCH3.
Geunhye Kim +8 more
wiley +1 more source
Advanced Science, EarlyView.Neuron‐derived MIF binds VCAM1 on gastric cancer cells and activates ERK/STAT3 signaling, leading to CXCL8 transcription and secretion. Tumor‐derived CXCL8 subsequently stimulates neuronal CXCR2 to enhance MIF production, establishing a self‐amplifying MIF–VCAM1–CXCL8 positive‐feedback loop that promotes perineural invasion, tumor progression, and ...
Xunjun Li +13 more
wiley +1 more source
The use of cold atmospheric plasma/J-Plasma in the management of rhinophyma: A case report
JPRAS OpenRhinophyma is a disfiguring swelling on the nose occurring due to the proliferation of sebaceous glands. The purpose of this case report is to describe clinical findings in a patient who presented with rhinophyma in the Kenyan setting and the application
Abdullahi A. Adan, Najma Jelle
doaj +1 more source
Advanced Science, EarlyView.Human neutrophils exist as two epigenetically imprinted subtypes defined by stable CD177 expression or absence — a ratio that persists across time, circadian rhythms, and inflammation. CD177− neutrophils display a distinct molecular landscape enriched in arginase 1 and lipid metabolism markers, accumulate in head‐and‐neck tumors, and associate with ...
Marcel Jung +39 more
wiley +1 more source