Results 21 to 30 of about 235,598 (309)
Molecules, 2016 Gout is caused by the overproduction of uric acid and the inefficient metabolism of dietary purines in humans. Current treatments of gout, which include anti-inflammatory drugs, cyclooxygenase-2 inhibitors, and systemic glucocorticoids, have harmful side-
Nishone Thompson +8 more
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Target binding triggers hierarchical phosphorylation of human Argonaute-2 to promote target release
eLife, 2022 Argonaute (Ago) proteins play a central role in post-transcriptional gene regulation through RNA interference (RNAi). Agos bind small RNAs (sRNAs) including small interfering RNAs (siRNAs) and microRNAs (miRNAs) to form the functional core of the RNA ...
Brianna Bibel +4 more
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Synthesis of Quaternary Heterocyclic Salts
Molecules, 2013 The microwave synthesis of twenty quaternary ammonium salts is described. The syntheses feature comparable yields to conventional synthetic methods reported in the current literature with reduced reaction times and the absence of solvent or minimal ...
Angela J. Winstead +4 more
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Excitatory and inhibitory D-serine binding to the NMDA receptor
eLife, 2022 N-methyl-D-aspartate receptors (NMDARs) uniquely require binding of two different neurotransmitter agonists for synaptic transmission. D-serine and glycine bind to one subunit, GluN1, while glutamate binds to the other, GluN2.
Remy A Yovanno +4 more
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New Journal of Physics, 2015 We have studied the three-body complex formation rate of the hydroxyl anion with molecular hydrogen at low temperatures. The formed cluster is found to quickly undergo internal proton transfer to a hydrogen anion–water complex.
Daniel Hauser +4 more
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Nano Biomedicine and Engineering, 2012 In this paper, we demonstrate the application of Metal-Assisted and Microwave-Accelerated Evaporative Crystallization (MA-MAEC) technique to rapid and selective crystallization of a small drug compound. i.e. acetaminophen.
Muzaffer Mohammed +4 more
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Nanomaterials, 2023 The study presents complementary experiments and quantum chemical DFT computations to reveal the molecular-level interactions of an advanced nanomaterial, porphyrin aluminum metal–organic framework (compound 2), with the volatile organic sulfur compound ...
Shaheed Ullah +2 more
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Cold-bonded biochar-rich lightweight aggregates for net-zero concrete
, 2023 An emerging strategy to remove CO2 from the atmosphere and compensate for the greenhouse-gas emissions of cement and concrete is based on incorporating biochar into concrete.
Pietro, Lura +3 more
core +1 more source
Nano Biomedicine and Engineering, 2015 We report the enhancement of chemiluminescence response of horseradish peroxidase (HRP) in bioassays by plasmonic surfaces, which are comprised of (i) silver island films (SIFs) and (ii) metal thin films (silver, gold, copper, and nickel, 1 nm thick ...
Biebele Abel +3 more
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Molecules, 2023 Flower-like cobalt–molybdenum mixed-oxide microspheres (CoMo-FMs) with hierarchical architecture were successfully synthesized via a hydrothermal process and subsequent calcination step. The characterization results show that CoMo-FMs were assembled from
Xinxiang Cao +6 more
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