Results 41 to 50 of about 55,316 (261)

Closed-form Expressions for Multiscatter Dark Matter Capture Rates

The Astrophysical Journal
Any astrophysical object can, in principle, serve as a probe of the interaction between dark matter (DM) and regular baryonic matter. This method is based on the potential observable consequences annihilations of captured DM have on the surface ...
Cosmin Ilie
doaj   +1 more source

DUNE Prospect for Leptophobic Dark Matter

Advances in High Energy Physics, 2020
Highly energetic proton/electron beam fixed-target experiments extend an opportunity to probe the sub-GeV dark matter and associated interactions. In this work, we have explored the sensitivity of DUNE (Deep Underground Neutrino Experiment) for sub-GeV ...
Sabeeha Naaz, Jyotsna Singh, R. B. Singh
doaj   +1 more source

The offsets between galaxies and their dark matter in Λ cold dark matter [PDF]

Monthly Notices of the Royal Astronomical Society: Letters, 2015
Abstract We use the ‘Evolution and Assembly of GaLaxies and their Environments’ (eagle) suite of hydrodynamical cosmological simulations to measure offsets between the centres of stellar and dark matter components of galaxies. We find that the vast majority (>95 per cent) of the simulated galaxies display an offset smaller than ...
Schaller, Matthieu, Robertson, Andrew, Massey, Richard, Bower, Richard G., Eke, Vincent R.   +4 more
openaire   +2 more sources

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Microlensing and Halo Cold Dark Matter

Physical Review Letters, 1995
We discuss the implications of the more than 50 microlensing events seen by the EROS, MACHO, and OGLE collaborations for the composition of the halo of our galaxy. The event rates indicate that the halo mass fraction in MACHO's is less than 30\%, consistent with expectations for a universe whose primary component is cold dark matter.
Gates, Evalyn I., Gyuk, Geza, Turner, Michael S.   +2 more
openaire   +3 more sources

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Constraints on anharmonic corrections of fuzzy dark matter

Journal of High Energy Physics, 2018
The cold dark matter (CDM) scenario has proved successful in cosmology. However, we lack a fundamental understanding of its microscopic nature. Moreover, the apparent disagreement between CDM predictions and subgalactic-structure observations has ...
J. A. R. Cembranos, A. L. Maroto, S. J. Núñez Jareño, H. Villarrubia-Rojo   +3 more
doaj   +1 more source

The fate of substructures in cold dark matter haloes [PDF]

Monthly Notices of the Royal Astronomical Society, 2009
14 pages, 11 figures.
Angulo, R.E., Lacey, C.G., Baugh, C.M., Frenk, C.S.   +3 more
openaire   +4 more sources

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

C-19 and Hot, Wide Star Streams

The Astrophysical Journal
The C-19 star stream has the abundance characteristics of an unusually metal-poor globular cluster but kinematically is uncharacteristically hot and wide for a cluster stream, having a line-of-sight velocity dispersion of 7  ±  2 km s ^−1 and a 1 σ width
Raymond G. Carlberg, Rodrigo Ibata, Nicolas F. Martin, Else Starkenburg, David S. Aguado, Khyati Malhan, Kim Venn, Zhen Yuan   +7 more
doaj   +1 more source