Results 61 to 70 of about 690,483 (329)

C-19 and Hot, Wide Star Streams

The Astrophysical Journal
The C-19 star stream has the abundance characteristics of an unusually metal-poor globular cluster but kinematically is uncharacteristically hot and wide for a cluster stream, having a line-of-sight velocity dispersion of 7  ±  2 km s ^−1 and a 1 σ width
Raymond G. Carlberg, Rodrigo Ibata, Nicolas F. Martin, Else Starkenburg, David S. Aguado, Khyati Malhan, Kim Venn, Zhen Yuan   +7 more
doaj   +1 more source

Subhaloes in Self-Interacting Galactic Dark Matter Haloes

, 2012
We present N-body simulations of a new class of self-interacting dark matter models, which do not violate any astrophysical constraints due to a non-power-law velocity dependence of the transfer cross section which is motivated by a Yukawa-like new gauge
Abraham Loeb, Arkani-Hamed, Bode, Boyarsky, Boylan-Kolchin, Boylan-Kolchin, Buckley, Burkert, Carlson, Colín, Colín, Craig, Davé, de Blok, de Laix, Diemand, D’Onghia, D’Onghia, Feng, Feng, Finkbeiner, Firmani, Gao, Gilmore, Gnedin, Goerdt, Guo, Hernquist, Jardel, Jesus Zavala, Kleyna, Klypin, Kochanek, Koda, Koposov, Kuzio de Naray, Loeb, Lovell, Macciò, Machacek, Mark Vogelsberger, Miralda Escudé, Moore, Moore, Navarro, Navarro, Neto, Papastergis, Peñarrubia, Pontzen, Randall, Spergel, Springel, Springel, Springel, Strigari, Villaescusa-Navarro, Walker, Walker, Wang, Wolf, Yoshida, Yoshida, Zavala   +63 more
core   +1 more source

Observational evidence for self-interacting cold dark matter [PDF]

, 2000
Cosmological models with cold dark matter composed of weakly interacting particles predict overly dense cores in the centers of galaxies and clusters and an overly large number of halos within the Local Group compared to actual observations.
A. A. de Laix, A. A. Klypin, A. Dekel, A. Kusenko, B. Moore, B. Moore, B. Moore, B.-A. Gradwohl, C. W. Stubbs, David N. Spergel, E. D. Carlson, G. Dvali, G. Dvali, G. Kauffmann, G. Quinlan, G. Starkman, G. Toth, J. A. Tyson, J. Dalcanton, J. Dalcanton, J. Dalcanton, J. F. Navarro, J. Goodman, J. J. Mohr, J. V. Kepner, L. Blitz, M. E. Machacek, M. M. MacLow, M. Mateo, M. Weinberg, M. Zwann, N. Bahcall, P. D. Sackett, Paul J. Steinhardt, R. A. C. Croft, R. A. Flores, R. Bernabei, R. Schaeffer, V. P. Debattista, W. H. Press, W. J. G. De Blok   +40 more
core   +2 more sources

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Spontaneous electro-weak symmetry breaking and cold dark matter

, 2006
In the standard model, the weak gauge bosons and fermions obtain mass after spontaneous electro-weak symmetry breaking, which is realized through one fundamental scalar field, namely Higgs field.
Bergstrom L, de Boer W, de Boer W, Djouadi A, Juste A, Kolb E W, Zhu Shou-Hua   +6 more
core   +1 more source

Scalar dark matter and cold stars [PDF]

Astroparticle Physics, 2006
In a medium composed of scalar particles with non-zero mass, the range of Van-der-Waals-type scalar mediated interactions among nucleons becomes infinite when the medium makes a transition to a Bose-Einstein condensed phase. We explore this phenomenon in an astrophysical context.
openaire   +2 more sources

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Electroweak loop contributions to the direct detection of wino dark matter

European Physical Journal C: Particles and Fields
Electroweak loop corrections to the matrix elements for the spin-independent scattering of cold dark matter particles on nuclei are generally small, typically below the uncertainty in the local density of cold dark matter. However, as shown in this paper,
John Ellis, Natsumi Nagata, Keith A. Olive, Jiaming Zheng   +3 more
doaj   +1 more source

A Lambda CDM bounce scenario [PDF]

, 2015
We study a contracting universe composed of cold dark matter and radiation, and with a positive cosmological constant. As is well known from standard cosmological perturbation theory, under the assumption of initial quantum vacuum fluctuations the ...
Cai, Y., Wilson-Ewing, E.
core   +3 more sources

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source