Results 61 to 70 of about 60,419 (262)
Annals of Clinical and Translational Neurology, EarlyView.Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao +6 more
wiley +1 more source
Accurate Inner Stellar Density Slopes from Projected Surface Densities in Galaxies
The Astrophysical JournalThe inner slope of the three-dimensional stellar density in dwarf galaxies ( ${\rho }^{{\prime} }[0]$ ) is a sensitive probe of possible departures from the collisionless cold dark matter (CDM) paradigm, since cored stellar distributions ( ${\rho ...
Jorge Sánchez Almeida
doaj +1 more source
ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan +9 more
wiley +1 more source
How Many Bursts Does It Take to Form a Core at the Center of a Galaxy?
The Astrophysical JournalWe present a novel method for systematically assessing the impact of the central potential fluctuations associated with bursty outflows on the structures of dark matter halos for classical and ultrafaint dwarf (UFD) galaxies.
Olivia Mostow +6 more
doaj +1 more source
Enhanced Strength and Corrosion Resistance of Ti‐13Nb‐12Ta‐10Zr‐4Sn Alloy by Aging Treatment
Advanced Engineering Materials, EarlyView.This work systematically investigates the effect of aging treatment on mechanical properties and corrosion behavior of vacuum arc‐melted Ti‐13Nb‐12Ta‐10Zr‐4Sn alloy. Owing to the increased α″ martensite, strength and corrosion resistance were significantly enhanced by aging treatment.
Yuhua Li +5 more
wiley +1 more source
Dark matter, sparticle spectroscopy and muon (g − 2) in SU(4) c × SU(2) L × SU(2) R
Journal of High Energy Physics, 2018 We explore the sparticle mass spectra including LSP dark matter within the framework of supersymmetric SU(4) c × SU(2) L × SU(2) R (422) models, taking into account the constraints from extensive LHC and cold dark matter searches.
M. E. Gómez +3 more
doaj +1 more source
Advanced Engineering Materials, EarlyView.Scandium (Sc)‐doped AlCoCrFeMo HEA coatings are fabricated via flame spraying with 0.1, 0.3, and 0.5 wt% Sc additions. Among these, the HEA‐Sc0.3 coating exhibits the highest corrosion resistance, indicated by a more positive corrosion potential and lower current density.
Pankaj Kumar +7 more
wiley +1 more source
, 2013 Based on observational tests of large scale structure and constraints on halo structure, dark matter is generally taken to be cold and essentially collisionless.
Fan, JiJi +3 more
core +1 more source
A Dislocation Perspective on Strength and Toughness in Ceramics
Advanced Engineering Materials, EarlyView.Dislocations in ceramics enjoy a long but yet under‐appreciated history. The three research waves for dislocations in ceramics highlight the topic evolution over the last 90 years. This review focuses on the impact of dislocation on strength and toughness in ceramics.
Xufei Fang
wiley +1 more source
Condensation of galactic cold dark matter
, 2016 We consider the steady-state regime describing the density profile of a dark matter halo, if dark matter is treated as a Hose-Linstein condensate. We first solve the fluid equation for canonical cold dark matter, obtaining a class of density profiles ...
Visinelli, Luca,
core +1 more source