Results 81 to 90 of about 801,925 (377)

Holographic interacting dark energy in the braneworld cosmology

open access: yes, 2007
We investigate a model of brane cosmology to find a unified description of the radiation-matter-dark energy universe. It is of the interacting holographic dark energy with a bulk-holographic matter $\chi$.
Cai R. G.   +7 more
core   +1 more source

Search for Neutrino Mass and Dark Matter in Underground Experiments [PDF]

open access: yes, 2002
Search for the neutrino mass and for cold dark matter in the Universe are at present two of the most exciting fields of particle physics and cosmology.
Klapdor-Kleingrothaus, H. V.
core   +2 more sources

Cold dark matter with MOND scaling

open access: yesPhysics Letters B, 2010
We provide a holographic dual description of Milgrom's scaling associated with galactic rotation curves. Our argument is based on the recent entropic reinterpretation of Newton's laws of motion. We propose a duality between cold dark matter and modified Newtonian dynamics (MOND).
Y. Jack Ng, Chiu Man Ho, Djordje Minic
openaire   +3 more sources

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation

open access: yesMolecular Oncology, EarlyView.
Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides   +13 more
wiley   +1 more source

Light neutralino dark matter in U(1)XSSM

open access: yesNuclear Physics B, 2021
The U(1)X extension of the minimal supersymmetric standard model (MSSM) is called as U(1)XSSM with the local gauge group SU(3)C×SU(2)L×U(1)Y×U(1)X. U(1)XSSM has three singlet Higgs superfields beyond MSSM.
Shu-Min Zhao   +5 more
doaj   +1 more source

Diversity of Dark Matter Density Profiles in the Galactic Dwarf Spheroidal Satellites [PDF]

open access: yesAstrophysical Journal, 2020
The core–cusp problem is one of the controversial issues in the standard paradigm of Λ cold dark matter (ΛCDM) theory. However, under the assumption of conventional spherical symmetry, the strong degeneracy among model parameters makes it unclear whether
Kohei Hayashi, M. Chiba, T. Ishiyama
semanticscholar   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

C-19 and Hot, Wide Star Streams

open access: yesThe Astrophysical Journal
The C-19 star stream has the abundance characteristics of an unusually metal-poor globular cluster but kinematically is uncharacteristically hot and wide for a cluster stream, having a line-of-sight velocity dispersion of 7  ±  2 km s ^−1 and a 1 σ width
Raymond G. Carlberg   +7 more
doaj   +1 more source

The Signatures of Self-interacting Dark Matter and Subhalo Disruption on Cluster Substructure

open access: yesThe Astrophysical Journal, 2022
The abundance, distribution, and inner structure of satellites of galaxy clusters can be sensitive probes of the properties of dark matter. We run 30 cosmological zoom-in simulations with self-interacting dark matter (SIDM), with a velocity-dependent ...
Joy Bhattacharyya   +6 more
doaj   +1 more source

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