Results 21 to 30 of about 61,202 (261)

The Effect of Drawing Deformation Rate Induced Inhomogeneous Local Distortion on Phase Transformation of 304H Stainless Wire

open access: yesMetals, 2020
The micro/macro magnetic properties, local element distribution, martensite transformation, and mechanical properties of 304H stainless wires are determined for two cold drawing chains.
Qinhua Xu   +9 more
doaj   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

The Role of Overloading on the Reduction of Residual Stress by Cyclic Loading in Cold-Drawn Prestressing Steel Wires

open access: yesApplied Sciences, 2017
Prestressing steel wires are commonly used as reinforcement elements in structures bearing fatigue loads. These wires are obtained by a conforming process called cold drawing, where a progressive reduction of the wire diameter is produced, causing ...
Jesús Toribio   +3 more
doaj   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

open access: yesFEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen   +5 more
wiley   +1 more source

Multi-pass cold rolling and wire drawing process of gadolinium and its magnetocaloric effect

open access: yesJournal of Materials Research and Technology, 2022
Owing to low ductility of magnetocaloric material (MCM)s, the plastic deformation process is quite challenging, and information available on the deformation process of MCMs is limited. In this study, the cold rolling and wire drawing processes of Gd wire
Jeong Hun Kim   +3 more
doaj   +1 more source

On the cold drawing of polymers

open access: yesComputers & Mathematics with Applications, 1985
The paper treats the nonhomogeneous deformation of a slender bar of a viscoelastic material, a polymer. The authors considers the range of conditions under which a neck is formed in the bar, although it at first may both lengthen and deepen, and eventually growths in length without further change of depth.
openaire   +1 more source

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

open access: yesFEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez   +4 more
wiley   +1 more source

Integrated PANoptosis Profiling Identifies Immunosuppressive Subtypes and a Prognostic Signature With Functional Validation of MLKL in Glioblastoma

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The prognosis of glioblastoma (GBM) remains highly unfavorable, largely due to high tumor heterogeneity and an immunosuppressive microenvironment. However, the functional role of PANoptosis in this context is poorly understood. Methods Patients were stratified via K‐means clustering. A risk score model was constructed using prognosis‐
Langfei Tian   +6 more
wiley   +1 more source

Nationwide Survey of Association Between Fever and Epileptic Seizure in CDKL5 Deficiency Disorder Revealed Therapeutic Implications

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective CDKL5 deficiency disorder (CDD) is a rare, severe developmental and epileptic encephalopathy. There is a pressing need to develop effective and sustainable therapeutic strategies. We aimed to investigate the causal association between febrile episodes and epileptic seizures for therapeutic implications in CDD patients.
Siyi Wang   +13 more
wiley   +1 more source

Practice of Cold Drawing Process Optimization of GCr15 Bearing Steel Rod

open access: yesTeshugang, 2015
The effect of draft, cone angle and length of sizing belt of drawing die, and drawing speed on drawing stress and drawing surface accuracy of bearing steel GCr15 (1. 01% C, 1. 58% Cr) Φ11 mm rod coil has been analyzed. The optimization process for Φ11 mm
王莹莹, 杨鹏远
doaj  

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