Results 61 to 70 of about 260,144 (267)

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

Innovative cold joining technologies based on tube forming

open access: yesManufacturing Review, 2015
This paper is focused on innovative cold joining technologies for connecting tubes and fixing tubes to sheets. The proposed technologies are based on the utilization of plastic instability waves in thin-walled tubes subjected to axial compression and may
Alves Luis M.   +2 more
doaj   +2 more sources

Material flow control in sheet-bulk metal forming processes using blasted tool surfaces

open access: yesMATEC Web of Conferences, 2018
Highly-integrated and closely-tolerated functional components can be produced by sheet-bulk metal forming which is the application of bulk forming operations on sheet metals.
Merklein Marion   +3 more
doaj   +1 more source

Automation of choosing technologies of cold massive forming

open access: yesВестник СибАДИ, 2017
The authors suggest to use the tables of possible variants, which contain the schemes of forming primary blanks and semi-finished products for subsequent operations and mathematical models to determine the optimal combination of number of stamping’s ...
I. I. Zavyalov   +3 more
doaj   +1 more source

Experimental Research and Numerical Modelling of the Cold Forming Process of the Inconel 625 Alloy Sheets Using Flexible Punch. [PDF]

open access: yesMaterials (Basel), 2023
Balcerzak M   +6 more
europepmc   +1 more source

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

open access: yesFEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi   +6 more
wiley   +1 more source

The influence of microstructure deformation on the corrosion resistance of cold formed stainless steel

open access: yesMATEC Web of Conferences, 2018
Rotary swaging is an incremental cold forming process to produce axisymmetric workpieces from rods and tubes. The process also induces changes of the microstructure of the material depending on the process parameters.
Bösing Ingmar   +6 more
doaj   +1 more source

Sustainable bioplastics manufacturing from renewable sources

open access: yesFEBS Open Bio, EarlyView.
Bioplastics are manufactured by using polymers from different bio‐based sources. These novel materials not only offer biodegradability but also possess various functional properties that make them suitable for diverse applications. Recent developments in the preparation of bioplastics are reported, highlighting the distinct properties of each type of ...
C. Valeria L. Giosafatto   +6 more
wiley   +1 more source

Finite Element Modelling of Cold Formed Stainless Steel Columns

open access: yesActa Polytechnica, 2005
This paper describes the results obtained from a finite element investigation into the load capacity of column members of lipped channel cross-section, cold formed from Type 304 stainless steel, subjected to concentric and eccentric compression loading ...
M. Macdonald, J. Rhodes
doaj  

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