Ionic mechanisms of spinal neuronal cold hypersensitivity in ciguatera. [PDF]
Eur J Neurosci, 2015 Cold hypersensitivity is evident in a range of neuropathies and can evoke sensations of paradoxical burning cold pain. Ciguatoxin poisoning is known to induce a pain syndrome caused by consumption of contaminated tropical fish that can persist for months
Patel R +3 more
europepmc +9 more sources
Efficacy and safety of sympathetic radiofrequency thermocoagulation in the treatment of cold hypersensitivity [PDF]
Frontiers in Neurology, 2022 BackgroundCold hypersensitivity (CH) is a sensation of cold in the limbs and (or) body of a patient in an environment that is not considered cold by unaffected people, or a strong feeling of cold at a relatively low temperature.
Yuefeng Liao +5 more
doaj +3 more sources
Exploratory study of cold hypersensitivity in Japanese women: genetic associations and somatic symptom burden [PDF]
Scientific ReportsTemperature perception is essential for humans to discern the environment and maintain homeostasis. However, some individuals experience cold hypersensitivity, characterized by a subjective feeling of coldness despite ambient environmental temperatures ...
Xuefeng Wu +11 more
doaj +3 more sources
Brain activity changes in a macaque model of oxaliplatin-induced neuropathic cold hypersensitivity [PDF]
Scientific Reports, 2017 The antineoplastic agent oxaliplatin induces a painful peripheral neuropathy characterized by an acute cold hypersensitivity. There is a lack of effective treatments to manage oxaliplatin-induced cold hypersensitivity which is due, in part, to a lack of ...
Kazuaki Nagasaka +4 more
doaj +3 more sources
Efficacy and safety of Onkyeong-tang in treating cold hypersensitivity in the feet of Korean women: protocol for a double-blind, randomized, placebo-controlled, parallel-group, multicenter clinical study [PDF]
Trials, 2020 Background Cold hypersensitivity in the hands and feet (CHHF) commonly affects Asian women, especially Korean women, and it negatively impacts the quality of life of the affected individuals.
Kyou-Young Lee +5 more
doaj +3 more sources
Efficacy and safety of Ojeok-san in Korean female patients with cold hypersensitivity in the hands and feet: study protocol for a randomized, double-blinded, placebo-controlled, multicenter pilot study [PDF]
Trials, 2018 Background This study aims to evaluate the safety, efficacy, and feasibility of a full randomized clinical trial of Ojeok-san in Korean female patients with cold hypersensitivity in the hands and feet. Methods This study is a multicenter, double-blinded,
Youme Ko +10 more
doaj +3 more sources
The definition and diagnosis of cold hypersensitivity in the hands and feet: Finding from the experts survey [PDF]
Integrative Medicine Research, 2018 Background: Cold hypersensitivity in the hands and feet (CHHF) is a symptom patients usually feel cold in their hands and feet, but not dealt with a disease in western medicine. However, it is often appealed by patients at a clinic of Korean medicine (KM)
Kwang-Ho Bae +12 more
doaj +3 more sources
Cold hypersensitivity in the lower extremities: an underappreciated symptom in patients with varicose veins [PDF]
Open HeartBackground This study aimed to investigate the frequently overlooked symptoms of cold hypersensitivity and heavy legs related to varicose veins in a large sample of patients.Methods Data on 8782 adults aged 30–70 years without a history of cancer were ...
Disline Manli Tantoh +5 more
doaj +2 more sources
Study Protocol for Multi-Center, Open-Label, Randomized Controlled Trial for Assessing the Efficacy and Safety of Electroacupuncture for Cold Hypersensitivity in Hands and Feet [PDF]
Journal of PharmacopunctureObjectives: Cold hypersensitivity in the hands and feet (CHHF) is defined as the symptom of a sensation of coldness in the extremities under conditions that are not considered cold by an unaffected person.
Kyou-Young Lee +5 more
doaj +2 more sources
TRPA1 contributes to cold hypersensitivity. [PDF]
J Neurosci, 2010 TRPA1 is a nonselective cation channel expressed by nociceptors. Although it is widely accepted that TRPA1 serves as a broad irritancy receptor for a variety of reactive chemicals, its role in cold sensation remains controversial. Here, we demonstrate that mild cooling markedly increases agonist-evoked rat TRPA1 currents.
del Camino D +17 more
europepmc +4 more sources