Results 41 to 50 of about 437,631 (265)

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Effect of nuclear spin symmetry in cold and ultracold reactions: D + para/ortho-H2

open access: yesNew Journal of Physics, 2015
We report results for reaction and vibrational quenching of the collision D with para-H _2 ( $v,j=0$ ) and ortho-H _2 ( $v,j=1$ ) at cold and ultracold temperatures.
Ionel Simbotin, Robin Côté
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Laser cooling Rydberg molecules—a detailed study of the helium dimer

open access: yesNew Journal of Physics
The helium dimer in its metastable triplet state is a promising candidate to be the first laser-cooled homonuclear molecule. An ultracold gas of He $_2^*$ would enable a new generation of precision measurements to test quantum electrodynamics for three ...
Lucía Verdegay   +4 more
doaj   +1 more source

A Zeeman slower for diatomic molecules

open access: yesNew Journal of Physics, 2018
We present a novel slowing scheme for beams of laser-coolable diatomic molecules reminiscent of Zeeman slowing of atomic beams. The scheme results in efficient compression of the one-dimensional velocity distribution to velocities trappable by magnetic ...
M Petzold   +4 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Isotopologue-selective laser cooling of molecules

open access: yesNew Journal of Physics
Direct laser cooling of molecules has made significant progress in recent years. However, the selective cooling and manipulation of generic molecular samples based on their isotopic composition, which is ubiquitous in atomic laser cooling, has not yet ...
Felix Kogel   +4 more
doaj   +1 more source

Magneto-optical trapping forces for atoms and molecules with complex level structures

open access: yesNew Journal of Physics, 2015
Laser cooling and magneto-optical trapping of molecules typically involves multiple transitions driven by several laser frequencies. We analyze how magneto-optical trapping forces depend on the angular momenta, F _l and F _u , and the g -factors, g _l ...
M R Tarbutt
doaj   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

Effects of cold stress on growth performance, serum biochemistry, intestinal barrier molecules, and adenosine monophosphate-activated protein kinase in broilers

open access: yesAnimal, 2021
The homeostasis dysfunctions caused by cold stress remain a threat to intestinal health, particularly for young broiler chickens. We hypothesized that adenosine monophosphate-activated protein kinase (AMPK) was involved in the regulation of cold stress ...
H.J. Zhou   +5 more
doaj   +1 more source

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