Results 31 to 40 of about 3,566,597 (273)

The United States and Neutral Countries in Europe, 1945–1991

open access: yes, 2019
The post-Cold War era has led to a proliferation of scholarship on U.S. policy toward four neutral European countries—Austria, Finland, Switzerland, and Sweden—during the Cold War. This article provides a survey of the latest literature on U.S.
Nilsson, Mikael,
core   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

Light storage and control of photon-photon interactions in a cold Rydberg gas [PDF]

open access: yes, 2013
The effect of strong interatomic interactions on an optical field stored in Rydberg states of a cold atomic gas is investigated. Due to their large dipole moments Rydberg atoms interact very strongly with each other.
MAXWELL, DANIEL,THOMAS
core  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

A New Constraint on the Relative Disorder of Magnetic Fields between Neutral Interstellar Medium Phases

open access: yesThe Astrophysical Journal
Utilizing Planck polarized dust emission maps at 353 GHz and large-area maps of the neutral hydrogen (H i ) cold neutral medium (CNM) fraction ( f _CNM ), we investigate the relationship between dust polarization fraction ( p _353 ) and f _CNM in the ...
Minjie Lei, S. E. Clark
doaj   +1 more source

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

open access: yesMolecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir   +9 more
wiley   +1 more source

On the regulation of the cold neutral medium mass fraction by magnetic fields

open access: yesMonthly Notices of the Royal Astronomical Society
ABSTRACT In the Galactic plane, the ratio of the cold H i mass to the total H i mass appears to remain approximately constant for Galactocentric radii, $R_{\mathrm{g}}$, between $\sim$10 and $\sim$20 kpc, despite differences in physical conditions.
Adriana Gazol   +1 more
openaire   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

open access: yesFEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao   +10 more
wiley   +1 more source

Thermomechanical Fatigue and Creep–Fatigue Interaction of Inconel 718 Additively Manufactured by Laser Beam Powder Bed Fusion

open access: yesAdvanced Engineering Materials, EarlyView.
Thermomechanical fatigue tests of laser beam powder bed fusion (PBF‐LB) Inconel 718 show that the additively manufactured material reaches almost the lifetimes of conventionally‐rolled material under no‐dwell conditions. Introducing dwell times at the maximum temperature markedly reduces the lifetimes due to pronounced grain boundary sliding associated
Stefan Guth   +6 more
wiley   +1 more source

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