Results 191 to 200 of about 7,568,305 (285)

Hyper‐Intense Tumor Peripheral Accumulation of Antibody‐Conjugated Iron Oxide Nanoparticles can Enable Breast Cancer Detection by Magnetic Particle Imaging

Advanced Science, EarlyView.
Tumor‐associated inflammation retains antibody‐targeted or non‐specific antibody conjugated nanoparticles within the tumor microenvironment. Magnetic Particle Imaging (MPI) enables non‐invasive detection and differentiation of tumors from other organs, owing to higher nanoparticle retention by inflammatory cells in the tumor periphery.
Preethi Korangath, Hayden Carlton, Theresa Wong, Sean Healy, Toby Sanders, Mason Song, Patrick W. Goodwill, Cordula Grüttner, Kathleen Gabrielson, Robert Ivkov   +9 more
wiley   +1 more source

Synergistic Grain Boundary and Phonon Engineering Enables Ultrahigh Thermoelectric Performance in Mg3(Sb, Bi)2‐Based Materials

Advanced Science, EarlyView.
Ta encapsulated melting and Cu doping synergistically engineer grain boundaries and phonon scattering in Mg3(Sb,Bi)2, enabling single‐crystal‐like carrier transport and high thermoelectric performance. ABSTRACT Thermoelectric Mg3(Sb, Bi)2 has emerged as a rising star in virtue of its promising thermoelectric performance and abundant constituent ...
Jingdan Lei, Kai Xu, Kunpeng Zhao, Junzhuo Zhou, Haotian Gao, Yifan Yuan, Tian‐Ran Wei, Min Zhu, Qihao Zhang, Franck Gascoin, Xun Shi   +10 more
wiley   +1 more source

Tau Aggregate Imaging and Transcriptomics of Alzheimer's Disease Brain at Different Stages of Disease

Advanced Science, EarlyView.
The protein aggregates and gene expression in the middle temporal gyrus (MTG) and somatosensory cortex (SOM) of the postmortem brains of 13 Alzheimer's disease patients were studied in detail, revealing that small hyperphosphorylated tau aggregates increase with Braak stage driven by microglial inflammation.
Elizabeth A. English, Dorothea Böken, Matthew W. Cotton, Matthew R. Cheetham, Johanna S. Jackson, Georg Meisl, John S. H. Danial, Paul M. Matthews, Nurun N. Fancy, David Klenerman   +9 more
wiley   +1 more source

Roles of Cold Plasma Treatment on the Functional Properties of Plant-Based Proteins. [PDF]

Int J Food Sci
Adejoh AO, Kpomblekou LA, Ekezie FGC, Bamidele TO, Aryee ANA, Onuh JO.   +5 more
europepmc   +1 more source

Chemotherapy‐Activated GSK3β‐DNMT1 Signaling Upregulates CD47 to Evade Macrophage Phagocytosis and Drive Temozolomide Resistance in Glioblastoma

Advanced Science, EarlyView.
Temozolomide treatment activates GSK3β, driving DNMT1 phosphorylation, destabilization, and CD47 promoter hypomethylation in glioblastoma. This epigenetic shift upregulates CD47, enabling TMZ‐treated GBM cells to evade macrophage phagocytosis, survive chemotherapy, and acquire resistance.
Jie Li, Shuai Ying, Yi Zhang, Jingjing Wang, Quan Wan, Lingli Gong, Daxing Xu, Zhenkun Yang, Hongnian Lu, Ying Yin, Xiangming Fang, Zhening Pu   +11 more
wiley   +1 more source

Deubiquitination of Vangl by USP6 and USP32 Regulates Planar Cell Polarity Signaling

Advanced Science, EarlyView.
Compartment‐specific deubiquitination controls Vangl dosage and planar cell polarity signaling. USP6 and USP32 regulate distinct subcellular pools of Vangl by removing distinct ubiquitin modifications from Vangl proteins. This regulatory mechanism safeguards PCP‐dependent embryonic morphogenesis, while aberrant USP32‐dependent stabilization of VANGL ...
Fangzi Zha, Di Feng, Ziru Xue, Zhiying Liu, Xiaochen Lin, Zhe Wang, Ling Xu, Jasper Fuk Woo Chan, Martin Cheung, Michael Shing Yan Huen, Yusong Guo, Kui Ming Chan, Yun Liu, Bo Gao   +13 more
wiley   +1 more source

Circulating succinate changes during acute cold exposure are not related with brown adipose tissue in humans. [PDF]

J Physiol Biochem
Osuna-Prieto FJ, Martinez-Tellez B, Sánchez-Delgado G, Acosta FM, Jurado-Fasoli L, Vendrell J, Ruiz JR, Fernández-Veledo S.   +7 more
europepmc   +1 more source

Cancer‐Associated Fibroblasts Promote Glucose Metabolic Reprogramming and Progression of Triple‐Negative Breast Cancer via Exosomal circFAD104‐Mediated Intercellular Communication

Advanced Science, EarlyView.
CAF‐derived exosomes deliver circFAD104 into TNBC cells, where it acts as a molecular scaffold that bridges the E3 ligase MARCHF8 and PGM1, promoting MARCHF8‐mediated K48‐linked ubiquitination and proteasomal degradation of PGM1. Loss of PGM1 redirects glucose‐phosphate flux from glycogen synthesis toward glycolysis, thereby driving stemness, EMT, and ...
Lei Wang, Xiaoyan Li, Yiran Liang, Yifei Wang, Yuhan Jin, Jianing Wang, Dan Luo, Yuxia Yang, Jingze Yang, Yaming Li, Tong Chen, Dianwen Han, Zekun Wang, Wenjing Zhao, Bing Chen, Lijuan Wang, Qifeng Yang   +16 more
wiley   +1 more source

Cold Atmospheric Plasma in Wound Healing: Molecular Mechanism of Action. [PDF]

Int J Mol Sci
Bińkowski D, Antoszewski B, Kasielska-Trojan A.   +2 more
europepmc   +1 more source

Interfacial Salinity–Transport Matching in 3D Solar Evaporators: A Framework for Brine‐Stable Solar Interfacial Evaporation

Advanced Science, EarlyView.
A transport‐matching framework is developed to evaluate brine‐stable 3D solar evaporators beyond evaporation rate alone. Using PVA/GNP porous evaporators as a model system, the study shows that stable brine evaporation requires balanced heat generation, liquid replenishment, salt redistribution, and vapor removal rather than maximum dry temperature or ...
Mohammad Sajad Sorayani Bafqi, Arun Prakash Aranga Raju, Omid Doustdar, Reza Nekouie Esfahani, Ali Sadaghiani   +4 more
wiley   +1 more source