Results 51 to 60 of about 66,872 (284)

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Simulations of a cold-air pool associated with elevated wintertime ozone in the Uintah Basin, Utah [PDF]

open access: yesAtmospheric Chemistry and Physics, 2015
Numerical simulations are used to investigate the meteorological characteristics of the 31 January–6 February 2013 cold-air pool in the Uintah Basin, Utah, and the resulting high ozone concentrations.
E. M. Neemann   +3 more
doaj   +1 more source

Mechanisms for convection triggering by cold pools

open access: yes, 2019
Cold pools are fundamental ingredients of deep convection. They contribute to organizing the subcloud layer and are considered key elements in triggering convective cells. It was long known that this could happen mechanically, through lifting by the cold
Kuang, Zhiming   +2 more
core   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Assessment of valley cold pools and clouds in a very high-resolution numerical weather prediction model [PDF]

open access: yesGeoscientific Model Development, 2015
The formation of cold air pools in valleys under stable conditions represents an important challenge for numerical weather prediction (NWP). The challenge is increased when the valleys that dominate cold pool formation are on scales unresolved by NWP ...
J. K. Hughes   +4 more
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

What levels of estrogen hormones can be found in swimming pool water?

open access: yesApplied Water Science, 2019
Estrogens are a group of sex hormones. The entry of this hormone into the human body causes premature puberty, breast, and uterus cancer, etc. Due to sustainability, harmful effects, and its skin absorption, the identification of this hormone in swimming
Nagma Roshan, Mohammad Mehdi Taghizadeh
doaj   +1 more source

Convective cold pools: characterization and soil moisture dependence [PDF]

open access: yes, 2016
2016 Fall.Includes bibliographical references.Convective cold pools play an important role in Earth's climate system. However, a common framework does not exist for conceptually defining and objectively identifying convective cold pools in observations ...
Kirby, Michael J., committee member   +4 more
core  

Effects of chronic cold treatment on root elongation and gene expression in "Arabidopsis thaliana" [PDF]

open access: yes, 2008
Low temperature is a major limitation of plant growth. Cold adaptation is important for the survival and distribution of plant species at high elevations and high latitudes.
Lee, Yang Ping
core   +1 more source

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