Results 31 to 40 of about 436,294 (261)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Development of a Predictive Model Linking Electrical Characteristics to Semi-Lethal Temperature in Potted Apple Trees with Validation on Mature Specimens

Agronomy
In the context of increasingly frequent extreme low-temperature events, developing a rapid and non-destructive method to evaluate plant cold tolerance is of great scientific significance for accurately assessing the cold hardiness of fruit trees. In this
Bo Sun, Shuaiyang Wu, Xiaohang Nie, Linguang Jia, Xueying Zhang, Ji Qian   +5 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Overexpression of StBBX14 Enhances Cold Tolerance in Potato

Plants
Potato (Solanum tuberosum L.) is an important food crop, but low temperature affects the potato growth and yield. In this study, the expression level of StBBX14 was significantly increased over 1 h and then gradually decreased under cold stress.
Heng Zhang, Mingjun Chen, Xiaobo Luo, Li Song, Fei Li   +4 more
doaj   +1 more source

Cold resistance of steel beam prestressed by wall drawing

Вестник СибАДИ, 2023
Introduction. The purpose of the article is a generalized analysis of existing methods for determining of structural steel elements behaviour in extreme conditions of subzero temperatures and their use to assess the cold resistance of steel beams ...
E. V. Kravchuk, I. Yu. Belutskii, V. A. Kravchuk   +2 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

SUSTAINABILITY OF BULGARIAN AND TURKISH VARIETIES AND LINES OF WINTER BARLEY TO ABIOTIC STRESS

Trakya University Journal of Natural Sciences, 2016
Cold resistance, drought resistance and water and temperature regime of 43 Bulgarian and Turkish winter barley varieties and lines were determined in field and laboratory conditions during the period 2005-2009. 50% of the study material was found to have
Dragomir Gospodinov Valchev, Darina Dimitrova Valcheva, Toshka Milkova Popova, Darina Mincheva Dimova, Irfan Ozturk, Recep Kaya   +5 more
doaj   +2 more sources

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source