Results 41 to 50 of about 1,318,533 (304)

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Formulation of a live bacterial vaccine for stable room temperature storage results in loss of acid, bile and bile salt resistance [PDF]

open access: yes, 2008
Live bacterial vaccines have great promise both as vaccines against enteric pathogens and as heterologous antigen vectors against diverse diseases. Ideally, room temperature stable dry formulations of live bacterial vaccines will allow oral vaccination ...
Edwards, Alexander D.   +1 more
core   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Cold resistance of steel beam prestressed by wall drawing

open access: yesВестник СибАДИ, 2023
Introduction. The purpose of the article is a generalized analysis of existing methods for determining of structural steel elements behaviour in extreme conditions of subzero temperatures and their use to assess the cold resistance of steel beams ...
E. V. Kravchuk   +2 more
doaj   +1 more source

Electronic circuit provides automatic level control for liquid nitrogen traps [PDF]

open access: yes, 1968
Electronic circuit, based on the principle of increased thermistor resistance corresponding to decreases in temperature provides an automatic level control for liquid nitrogen cold traps.
Turvy, R. R.
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Development of a Predictive Model Linking Electrical Characteristics to Semi-Lethal Temperature in Potted Apple Trees with Validation on Mature Specimens

open access: yesAgronomy
In the context of increasingly frequent extreme low-temperature events, developing a rapid and non-destructive method to evaluate plant cold tolerance is of great scientific significance for accurately assessing the cold hardiness of fruit trees. In this
Bo Sun   +5 more
doaj   +1 more source

Highly Abrasion-resistant and Long-lasting Concrete [PDF]

open access: yes, 2019
Studded tire usage in Alaska contributes to rutting damage on pavements resulting in high maintenance costs and safety issues. In this study binary, ternary, and quaternary highly-abrasion resistant concrete mix designs, using supplementary cementitious ...
Liu, Jenny, Murph, Diane
core  

Proteome expression patterns in the stress tolerant evergreen Ammopiptanthus nanus under conditions of extreme cold [PDF]

open access: yes, 2010
Low temperature is one of the important environmental changes that affect plant growth. The cold resistance capabilities of evergreen plants are the result of long-term adaptation to extreme environmental conditions.
Chunfang   +6 more
core   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

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