Results 41 to 50 of about 2,316,496 (284)
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Modeling and validation of water-cooled trapping under natural conditions
Xi'an Gongcheng Daxue xuebao, 2023 To address the question of whether cold capture can store cold in different regions in winter, and to realize the energy-saving concept of capturing winter cold storage for summer use, the mathematical modeling and experimental demonstration of the cold ...
SUN Tiezhu, WANG Qi, MA Jie
doaj +1 more source
Ciência Florestal, 2010 The seeds of Araucaria angustifolia (Bertol.) Kuntze are recalcitrants and, therefore, they lose rapidly the viability after the harvest, limiting their use for nursery production of seedlings. This work was carried out to investigate the effects of cold
Álvaro Valente Caçola +3 more
doaj +1 more source
Movable solar powered cold storage for fruits and vegetables
The Indian Journal of Agricultural Sciences, 2021 A solar powered portable cold storage system was designed and developed in 2017-18 for storage of fresh fruits and vegetables to increase the shelf life. The capacity of the cooling chamber is 3.88 m3. The cold store was operated at three temperatures 8,
P K SHARMA
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Light storage and control of photon-photon interactions in a cold Rydberg gas [PDF]
, 2013 The effect of strong interatomic interactions on an optical field stored in Rydberg states of a cold atomic gas is investigated. Due to their large dipole moments Rydberg atoms interact very strongly with each other.
MAXWELL, DANIEL,THOMAS
core
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Ngineering Studies on,Storage of ,Onion Crop [PDF]
Journal of Soil Sciences and Agricultural Engineering, 2005 A study was carried out to compare and evaluate three different storage methods of onion (traditional storage, ventilated storsce and cold storage).
M. El-Sayed +3 more
doaj +1 more source
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
Cold Storage and Release Characteristics of Phase Change Cold Storage Plate with Non-Uniform Fins
EnergiesIce plates, widely used in food cold chain refrigeration transportation, involve challenges such as long cold storage time and low efficiency in use. This study establishes a mathematical model for ice plate cold storage and release.
Kun Wu, Haibo Zhao, Ye Wang
doaj +1 more source
Molecular Oncology, EarlyView.We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth +17 more
wiley +1 more source