Results 51 to 60 of about 939,961 (305)

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Improving the Imaging Quality of Ghost Imaging Lidar via Sparsity Constraint by Time-Resolved Technique

Remote Sensing, 2016
Ghost imaging via sparsity constraint (GISC)—which is developing into a new staring imaging lidar—can obtain both the range information and spatial distribution of a remote target with the use of the measurements below the Nyquist limit.
Wenlin Gong, Hong Yu, Chengqiang Zhao, Zunwang Bo, Mingliang Chen, Wendong Xu   +5 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

The influence of stacking mode and air supply power on cooling effect of cold storage

Shipin yu jixie
Objective: Reasonable planning of the stacking of goods in the mobile cold storage and reasonable design of the air supply power of the fan, to reduce cold storage energy consumption and improve economic efficiency.
XU Jing, WANG Feng, TAN Zhenhua, LU Qiufang   +3 more
doaj   +1 more source

Coupled Cooling Method and Application of Latent Heat Thermal Energy Storage Combined with Pre-cooling of Envelope: Optimization of Pre-cooling with Intermittent Mode [PDF]

, 2018
This document is the Accepted Manuscript version of the following article: Xiangkui Gao, Yanping Yuan, Hongwei Wu, Xiaoling Cao, and Xudong Zhao, ‘Coupled cooling method and application of latent heat thermal energy storage combined with pre-cooling of ...
Cao, Xiaoling, Gao, Xiangkui, Wu, Hongwei, Yuan, Yanping, Zhao, Xudong   +4 more
core   +2 more sources

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

FEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori, Kohei Kawabata, Takanori Kubo, Takeo Kitazawa, Sae Kanai, Madoka Iwashita, Ami Hayashi, Hiroyuki Nishi, Mikihisa Takano   +8 more
wiley   +1 more source

Assessment of medicines cold chain storage conformity with the requirements of the World Health Organization in health facilities of the Eastern Province of Rwanda

Journal of Pharmaceutical Policy and Practice, 2023
Background Despite the prominent evidence of cold chain monitoring in the health system to reduce wastage and maintain product potency, there are still inefficiencies in the storage and transportation of cold chain products.
Joseph Désiré Nyirimanzi, Joseph Ngenzi, Védaste Kagisha, Thomas Bizimana, Egide Kayitare   +4 more
doaj   +1 more source

A note on the effect of calcium alginate coating on quality of refrigerated strawberries. [PDF]

, 2010
peer-reviewedAn alginate-based edible coating was investigated for the preservation of the quality of strawberries during cold storage (5 °C). Strawberries were immersed, successively, in sodium alginate and calcium chloride solutions to generate a ...
Ehsani, M.R., Emamdjomeh, Z., Mazaheri Asadi, M., Mazaheri, A.F., Mizani, M., Moayednia, N.   +5 more
core  

Storage and Retrieval of a Squeezed Vacuum

, 2008
Storage and retrieval of a squeezed vacuum was successfully demonstrated using electromagnetically induced transparency. 930ns of the squeezed vacuum pulse was incident on the laser cooled 87Rb atoms with an intense control light in a coherent state ...
Akira Furusawa, Daisuke Akamatsu, Kazuhito Honda, Keiichirou Akiba, M. Kourogi, Manabu Arikawa, Mikio Kozuma, Satoshi Nagatsuka, Takahito Tanimura, Yoshihiko Yokoi   +9 more
core   +1 more source

Techno-economic performance evaluation of solar tower plants with integrated multilayered PCM thermocline thermal energy storage: a comparative study to conventional two-tank storage systems [PDF]

, 2015
Copyright 2016 AIP Publishing. This article may be downloaded for personal use only. Any other use requires prior permission of the author and AIP Publishing.Solar Tower Power Plants with thermal energy storage are a promising technology for dispatchable
Arnaudo, Monica, Ferruzza, Davide, Guedéz, Rafael, Hassar, Zhor, Laumert, Björn, Pérez Segarra, Carlos David, Rodríguez Pérez, Ivette María   +6 more
core   +3 more sources