Results 71 to 80 of about 977,695 (302)
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Die Koue Oorlog: Die Wêreld se Langste Oorlog? / The Cold War: The World's Longest War?
Scientia Militaria, 2012 The Cold War is a war that was never declared and never terminated. Historians differ rather seriously on when, how and where it began. They do not, however, differ on the fact that it simply faded away at the end of the eighties, but they assign ...
P.H. Kapp
doaj +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Tracing Cold War in Post-Modern Management's Hot Issues [PDF]
Tracing Cold War in post-modern managerial science and ideology one encounters hot issues linking contemporary liberal dogmas and romanticized view of organizational leadership to the dismantling of a welfare state disguised as a liberation of an ...
Magala, S.J.
core +1 more source
The Enduring Challenge: Self Determination and Ethnic Conflict in the 21st Century [PDF]
, 2002 Explores the ways in which ethnic conflicts have had a major impact on international security and U.S. foreign policy since the end of the Cold War, and looks at the role of international organizations and NGOs in addressing self-determination ...
David Callahan
core
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
The Horne Thesis and Cold War Japan
HistoriesGerald Horne’s explication of Cold War-era political history as negotiated white supremacy leads to an enhanced understanding of Japan in the Cold War.
Jason Michael Morgan
doaj +1 more source
, 2014 This paper presents a comparison between President Eisenhower and President Kennedy\u27s foreign affairs policies, specifically regarding the Cold War, by examining the presidents\u27 interactions with four distinct Cold War ...
Nosti, Andrew C.
core
Security governance and networks: New theoretical perspectives in transatlantic security [PDF]
, 2005 The end of the Cold War has not only witnessed the rise of new transnational threats such as terrorism, crime, proliferation and civil war; it has also seen the growing role of non-state actors in the provision of security in Europe and North America ...
Alberts DS +36 more
core +1 more source