The Enduring Challenge: Self Determination and Ethnic Conflict in the 21st Century [PDF]
, 2002 Explores the ways in which ethnic conflicts have had a major impact on international security and U.S. foreign policy since the end of the Cold War, and looks at the role of international organizations and NGOs in addressing self-determination ...
David Callahan
core
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Mutually assured construction : resurrecting the West Texas missile silos [PDF]
, 2016 A group of enthusiasts near Abilene, Texas are turning decommissioned, Cold War-era nuclear missile silos into homes, doomsday shelters, historical monuments and businesses, offering a unique glimpse into the blue-collar, do-it-yourself psyche of a ...
East, Andrew Joseph
core +1 more source
TREX1, a predator for treating MSI‐H tumors?
Molecular Oncology, EarlyView.Immunotherapy benefits many patients; yet, some with MSI‐H tumors remain unresponsive despite their high immunogenicity. Xu et al. reveal that TREX1 enables immune evasion by degrading cytosolic DNA and suppressing cGAS–STING–IFN‐I signaling. TREX1 loss restores DNA sensing, increases CD8+ T and NK cell infiltration, and boosts antitumor immunity ...
Elena Benidovskaya +2 more
wiley +1 more source
Práticas da História, 2017 Odd Arne Westad is a historian whose work largely focuses on the Cold War as well as on Chinese and East Asian history. He is best known as a key voice of ‘new Cold War history’, an expanding field which, since the turn of the century, has sought ...
Rui Lopes
doaj +1 more source
Gukurahundi and Zimbabwe’s Place in the 1980s Cold War [PDF]
, 2023 Timothy Lewis Scarnecchia
openalex +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Multilateral security in the Mediterranean post-Cold War: NATO’s Mediterranean Dialogue and the EuroMed Partnership. Jean Monnet/Robert Schuman Paper Series Vol. 7 No. 10 May 2007 [PDF]
, 2007 [From the introduction]. In this paper I will compare and contrast how the multilateral efforts in terms of NATO’s Mediterranean Dialogue (“Dialogue”) program, involving i.a. U.S.
Boening, Astrid B.
core
Twenty Years After the Fall of the Berlin Wall, How We Misremember the Cold War [PDF]
, 2009 Twenty years ago this week, the Berlin Wall was taken down ending the division of that city and, symbolically, Germany and all of Europe. Within two years of that event, the Soviet Union itself dissolved and the Cold War was over.
Mitchell, Lincoln A.
core +2 more sources
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source