Results 81 to 90 of about 977,695 (302)

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Repensar a América Latina na Guerra Fria como parte do Sul Global

open access: yesRevista de História, 2021
Resenha do Livro: FIELD Jr, Thomas C.; KREPP, Stella; PETTINÀ Vanni (ed.). Latin America and the Global Cold War. The New Cold War history. Chapel Hill: The University of North Carolina Press, 2020, 440p.
Flóres Giorgini
doaj  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

The Korean Armistice of 1953 and its Consequences - Part II [PDF]

open access: yes
Mitter: China emerged from the Korean War as a more confident actor in the international order. The paper considers three wider contexts within which China's experience of the Korean War should be considered: as part of a spectrum of 20th century wars ...
Koji Nakakita, Rana Mitter
core  

Beyond the Cold War: New Directions for Labor Internationalism [PDF]

open access: yes, 1989
[Excerpt] Achieving real solidarity across national borders and around the globe is a difficult undertaking, one which little in our experience has prepared us for.
Garver, Paul
core   +1 more source

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

open access: yesFEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang   +7 more
wiley   +1 more source

“I’ve Got a Hunch We’re Going Around in Circles”: Exceptions to American Exceptionalism in Hollywood Korean War Films

open access: yesAmerican Studies in Scandinavia, 2017
Hollywood Korean War films primarily aimed at integrating American citizenry into national narratives of cohesion and teleology by displacing contradictions onto the exteriority of American identity. The films dismiss the Korean War as not worth fighting
Junghyun Hwang
doaj   +1 more source

Cold War Revival: Neoconservatives and Historical Memory in the War on Terror [PDF]

open access: yes, 2007
Throughout the cold war, neoconservative intellectuals argued that the United States is an inherently virtuous nation engaged a permanent struggle against enemies at home as well as abroad. This essay addresses the ways that contemporary neoconservative
Noon, David Hoogland
core   +3 more sources

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

open access: yesFEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori   +8 more
wiley   +1 more source

Twenty Years After the Fall of the Berlin Wall, How We Misremember the Cold War [PDF]

open access: yes, 2009
Twenty years ago this week, the Berlin Wall was taken down ending the division of that city and, symbolically, Germany and all of Europe. Within two years of that event, the Soviet Union itself dissolved and the Cold War was over.
Mitchell, Lincoln A.
core   +2 more sources

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