Results 131 to 140 of about 53,624 (264)

Reshaping study design for faster extrapolation‐based drug approval in pediatric inflammatory bowel diseases: An ESPGHAN–NASPGHAN position paper

Journal of Pediatric Gastroenterology and Nutrition, Volume 82, Issue 3, Page 867-894, March 2026.
Abstract Children with inflammatory bowel diseases (IBD) have limited access to the available advanced therapies, given the lengthy gap between adult and pediatric approval. We aimed to review key hurdles for pediatric trials and recommend practical solutions.
Dan Turner, Amit Assa, Mikkel Malham, Shira Yuval Bar‐Asher, Carla Rayan, Jeffrey S. Hyams, Holm H. Uhlig, Brad Pasternak, David C. Wilson, Hilary K. Michel, Lissy de Ridder, Eric Zuckerman, Marina Aloi, Peter Szitanyi, Marla C. Dubinsky, Anne M. Griffiths, Roberto Saldana, Javier Martín‐de‐Carpi, Eytan Wine, Richard K. Russell, Jeremy Adler, Joseph Picoraro   +21 more
wiley   +1 more source

Long-term results of medical treatment in patients with a severe attack of ulcerative colitis

Терапевтический архив, 2015
Aim. To assess the long-term result of medical treatment in patients with a severe attack (SA) of ulcerative colitis (UC). Subjects and methods. The course of UC was analyzed in 56 patients who were accessible by telephone contact and consecutively ...
I L Khalif, B A Nanaeva, A O Golovenko, O V Golovenko   +3 more
doaj  

Duodenitis associated with ulcerative colitis and pouchitis after total colectomy successfully treated with upadacitinib: A case report

DEN Open
A 27‐year‐old man had ulcerative colitis (UC) 1 year prior and underwent a colectomy and two‐stage ileal pouch‐anal anastomosis for medically refractory UC 6 months ago.
Kentaro Kojima, Jun Takada, Kiichi Otani, Naoya Masuda, Yukari Tezuka, Sachiyo Onishi, Masaya Kubota, Takashi Ibuka, Masahito Shimizu   +8 more
doaj   +1 more source

Effect of the rs7858836 Single‐Nucleotide Polymorphisms of the ASTN2 Gene on Pain‐Related Phenotypes in Japanese Women Who Underwent Laparoscopic Gynecologic Surgery

Neuropsychopharmacology Reports, Volume 46, Issue 1, March 2026.
Schematic overview of the study examining the association between the ASTN2 rs7858836 T allele and postoperative pain–related phenotypes in humans. The analysis focuses on the relationship between this genetic variant and postoperative pain intensity as well as analgesic responses.
Rie Inoue, Daisuke Nishizawa, Shoko Okahara, Atsuko Hara, Hisako Okada, Junko Hasegawa, Yuko Ebata, Kyoko Nakayama, Masakazu Hayashida, Kazutaka Ikeda   +9 more
wiley   +1 more source

Videolaparo-assisted subtotal colectomy with cecorectal anastomosis in the treatment of chronic slow transit constipation [PDF]

, 2010
Mechanical cecorectal anastomosis after subtotal colectomy, in the treatment of slow transit constipation, probably represents the most attractive surgical alternative to total colectomy and ileorectal anastomosis.
Candillo, Giuseppe, Celsi, Salvatore, Conzo, Giovanni, Della Pietra, Cristina, Livrea, Antonio, Palazzo, Antonietta, Stanzione, Francesco   +6 more
core  

Pleural Infection as the First Presentation of a Large Retroperitoneal Abscess

Respirology Case Reports, Volume 14, Issue 3, March 2026.
This case report describes an 81‐year‐old male patient with an empyema secondary to a retroperitoneal abscess. He was found to have a large hiatus hernia and communication between the retroperitoneal and pleural spaces via a diaphragmatic defect.
Sugam Dhakal, Edward Fysh, Yi Jin Kuok, Y. C. Gary Lee   +3 more
wiley   +1 more source

Corticosteroid Use in Childhood‐Onset Inflammatory Bowel Disease: A Nationwide Cohort Study (2006–2022)

United European Gastroenterology Journal, Volume 14, Issue 2, March 2026.
ABSTRACT Background We aimed to determine corticosteroid (CS) use in paediatric inflammatory bowel disease (PIBD, < 18 years), which remains common despite recommendations for limited use and the emergence of steroid‐sparing therapies. Methods We conducted a study of all children in Sweden diagnosed with CD (n = 2460) or UC (n = 2470) in 2006–2022 ...
Karl Mårild, Mikkel Malham, Petter Malmborg, Jonas Söderling, Mads Damsgaard Wewer, Vibeke Wewer, SWIBREG Study Group, Tim Raine, Johan Burisch, Ola Olén, Malin Olsson, Pär Myrelid, Hans Strid, Charlotte Hedin, Susanna Jäghult, Jonas Halfvarson, Caroline Nordenvall, Martin Rejler, Olof Grip, Ulrika L. Fagerberg, Pontus Karling   +20 more
wiley   +1 more source

Sex‐ and Age‐Stratified Outcomes of Colonoscopy Versus Faecal Immunochemical Testing: Post‐Analysis of the COLONPREV Study

United European Gastroenterology Journal, Volume 14, Issue 2, March 2026.
ABSTRACT Background Colorectal cancer (CRC) screening is effective and cost‐effective in average‐risk individuals. The COLONPREV study recently showed that individuals invited to a faecal immunochemical test (FIT) were more likely to participate in screening than those invited to colonoscopy, and that FIT‐based screening was non‐inferior to colonoscopy
Antoni Castells, Enrique Quintero, Miquel Serra‐Burriel, Luis Bujanda, Susana Castán‐Cameo, Joaquín Cubiella, José Díaz‐Tasende, Ángel Lanas, Akiko Ono, Blanca Coll‐Vinent, Eladio Frías‐Arrocha, Cristina Hernández, Rodrigo Jover, Montserrat Andreu, Fernando Carballo, Juan Diego Morillas, Dolores Salas, on behalf of the COLONPREV study investigators   +17 more
wiley   +1 more source

Assessing Age‐Specific Variability in Microplastic Intake Through Seafood Consumption: A Case Study in Central Java, Indonesia

Journal of Food Science, Volume 91, Issue 3, March 2026.
ABSTRACT Microplastics (MPs) are frequently detected in seafood. However, the extent to which seafood consumption contributes to MP intake remains uncertain. Previous studies on MP intake in humans did not consider interindividual variability in exposure.
Inneke Hantoro, Jiaqi Wang, Ansje J. Löhr, Frank G. A. J. Van Belleghem, Budi Widianarko, Ad M. J. Ragas   +5 more
wiley   +1 more source

Impact of Schizophrenia Spectrum Disorders on the Receipt of Invasive and Systemic Therapy for Colorectal Cancer: A Nationwide Multicenter Retrospective Cohort Study in Japan

Acta Psychiatrica Scandinavica, Volume 153, Issue 3, Page 191-199, March 2026.
ABSTRACT Introduction This study examined treatment disparities for colorectal cancer among patients diagnosed with schizophrenia spectrum disorders (SSD), focusing on invasive treatments and stage‐appropriate systemic therapy within a universal healthcare system.
Masaki Fujiwara, Yuto Yamada, Taisuke Ishii, Tomone Watanabe, Maiko Fujimori, Naoki Nakaya, Toshihiko Kawamura, Koji Otsuki, Kunitoshi Shigeyasu, Taichi Shimazu, Shiro Hinotsu, Yosuke Uchitomi, Masatoshi Inagaki   +12 more
wiley   +1 more source