Results 41 to 50 of about 44,973 (223)

Risk of Acute Kidney Injury Associated With Nephrotoxic Burden in Hospitalized Patients: A Scoping Review

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Limited evidence exists synthesizing the risk of acute kidney injury (AKI) associated with the concomitant administration of multiple nephrotoxic drugs, and even less examining the concept of nephrotoxic burden. The objective of this scoping review was to (1) identify definitions of nephrotoxic burden; (2) methods used to quantify (use of calculations)
Wafa Alatawi   +6 more
wiley   +1 more source

RORγt‐APCs: The New Masters of Oral Tolerance

open access: yesBarrier Immunity, EarlyView.
ABSTRACT Oral tolerance is defined by the hypo‐responsiveness of our body to fed antigens, and its failure can lead to immune‐mediated diseases, such as allergy, chronic inflammation and autoimmune diseases. Decades of research have demonstrated that antigen‐presenting cells (APCs) promote oral tolerance by inducing regulatory T cells (Tregs) and/or ...
Thierry Gauthier, WanJun Chen
wiley   +1 more source

Colistin Resistance and Management of Drug Resistant Infections

open access: yesCanadian Journal of Infectious Diseases and Medical Microbiology, 2022
Colistin resistance is a globalized sensible issue because it has been considered a drug of the last-line resort to treat drug-resistant bacterial infections.
Juhi Sharma   +3 more
doaj   +1 more source

Progress in the detection of gut microbiota based on microfluidic technology

open access: yesInterdisciplinary Medicine, EarlyView.
Abstract Gut microbiota, a complex microbial community in the human intestine, are vital for digestion, nutrient absorption, and immune regulation, maintaining gut micro‐ecological balance. Accurate detection of its composition, structure, and function is crucial for understanding the relationship between health and disease, early disease diagnosis ...
Yuan Tan   +3 more
wiley   +1 more source

Combining Colistin with Furanone C-30 Rescues Colistin Resistance of Gram-Negative Bacteria in Vitro and in Vivo

open access: yesMicrobiology Spectrum, 2021
The spread of multidrug-resistant (MDR) Gram-negative bacteria (GNB) has led to serious public health problems worldwide. Colistin, as a “last resort” for the treatment of MDR bacterial infections, has been used significantly in recent years and has led ...
Ying Zhang   +10 more
doaj   +1 more source

Oxidative Treatment for Reducing Persistent Populations of Escherichia coli Under Amoxicillin and Gentamicin Pressure

open access: yesJournal of Biophotonics, EarlyView.
Photodynamic inactivation (PDI) with methylene blue and 660 nm LED enhances antibiotic killing of bacteria, accelerating time‐kill kinetics and reducing the MDK99 compared to antibiotics alone. SEM confirms effective cellular damage, demonstrating that PDI potentiates amoxicillin and gentamicin against tolerant bacterial populations. ABSTRACT Bacterial
Bruna C. Correa   +3 more
wiley   +1 more source

Combined With Mefloquine, Resurrect Colistin Active in Colistin-Resistant Pseudomonas aeruginosa in vitro and in vivo [PDF]

open access: gold, 2021
Xiaodong Zhang   +10 more
openalex   +1 more source

Sensory, proximate, and microbiological quality evaluation of five commercially important native and imported dry fish in Bangladesh

open access: yesJSFA reports, EarlyView.
Abstract Background Dried fish is a popular protein‐rich food in Bangladesh, yet its safety and quality vary based on its origin, processing, and storage conditions. This study evaluated the sensory, proximate, and microbiological qualities of five commercially important dry fish available in Bangladeshi markets, including both native (Bangladesh) and ...
Nur Nahar Sohe   +2 more
wiley   +1 more source

Colistin for pneumonia involving multidrug-resistant Acinetobacter calcoaceticus-Acinetobacter baumannii complex

open access: yesJournal of Microbiology, Immunology and Infection, 2020
Objectives: To investigate clinical and microbiological response, and 30-day mortality of pneumonia involving multidrug-resistant (MDR) Acinetobacter calcoaceticus-Acinetobacter baumannii (Acb) complex treated with colistin, and identify associated ...
Jun-Yuan Zheng   +3 more
doaj   +1 more source

From Membrane Composition to Antimicrobial Strategies: Experimental and Computational Approaches to AMP Design and Selectivity

open access: yesSmall, EarlyView.
Antimicrobial peptides (AMPs) are promising candidates for next‐generation antibiotics, acting through mechanisms such as membrane disruption and intracellular targeting. This review examines how variations in bacterial membrane composition critically influence AMP activity.
Paolo Rossetti   +5 more
wiley   +1 more source

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