Results 21 to 30 of about 71,995 (190)

Clonal expansion of colistin-resistant Acinetobacter baumannii isolates in Cape Town, South Africa

open access: yesInternational Journal of Infectious Diseases, 2020
Objectives: To describe colistin-resistant Acinetobacter baumannii isolates in Cape Town, South Africa. Methods: A. baumannii isolates identified on Vitek 2 Advanced Expert System were collected from Tygerberg Hospital referral laboratory between 2016 ...
Yolandi Snyman   +5 more
doaj   +1 more source

Old drug, new findings: colistin resistance and dependence of [PDF]

open access: yesPrecision and Future Medicine, 2017
Colistin is an old drug, and its use has recently resurged because of increasing antibiotic resistance in gram-negative bacteria such as Acinetobacter baumannii.
Kwan Soo Ko, Yujin Choi, Ji-Young Lee
doaj   +1 more source

Colistin Dependency among Colistin-Heteroresistant Acinetobacter baumannii Isolates

open access: yesMicroorganisms, 2021
Colistin dependent (CD) isolates are dependent on colistin for optimal growth. Here we aimed to systematically determine the emergence of CD among colistin-heteroresistant carbapenem-resistant Acinetobacter baumannii (CRAB) isolates. We also examined the
Hadas Kon   +6 more
doaj   +1 more source

National survey of colistin resistance among carbapenemase-producing Enterobacteriaceae and outbreak caused by colistin-resistant OXA-48-producing Klebsiella pneumoniae, France, 2014 [PDF]

open access: yes, 2016
From January 2014 to December 2014, 972 consecutive non-replicate carbapenemase-producing Enterobacteriaceae isolates from colonised or infected patients were collected at the Associated French National Reference Centre as part of the French national ...
Dortet, L   +3 more
core   +1 more source

Role of efflux pumps, their inhibitors, and regulators in colistin resistance

open access: yesFrontiers in Microbiology, 2023
Colistin is highly promising against multidrug-resistant and extensively drug-resistant bacteria clinically. Bacteria are resistant to colistin mainly through mcr and chromosome-mediated lipopolysaccharide (LPS) synthesis-related locus variation. However,
Yinhuan Ding   +9 more
doaj   +1 more source

In vitro Activity of Pentamidine Alone and in Combination With Aminoglycosides, Tigecycline, Rifampicin, and Doripenem Against Clinical Strains of Carbapenemase-Producing and/or Colistin-Resistant Enterobacteriaceae [PDF]

open access: yes, 2018
Enterobacteriaceae cause different types of community- and hospital-acquired infections. Moreover, the spread of multidrug-resistant Enterobacteriaceae is a public health problem and the World Health Organization pointed them among the pathogens in which
Cebrero Cangueiro, Tania   +4 more
core   +1 more source

Preferential Selection of Low-Frequency, Lipopolysaccharide-Modified, Colistin-Resistant Mutants with a Combination of Antimicrobials in Acinetobacter baumannii

open access: yesMicrobiology Spectrum, 2022
Colistin, which targets lipopolysaccharide (LPS), is used as a last-resort drug against severe infections caused by drug-resistant Acinetobacter baumannii. However, A. baumannii possesses two colistin-resistance mechanisms.
Go Kamoshida   +14 more
doaj   +1 more source

Attributable deaths and disability-adjusted life-years caused by infections with antibiotic-resistant bacteria in the EU and the European Economic Area in 2015: a population-level modelling analysis [PDF]

open access: yes, 2018
Background: Infections due to antibiotic-resistant bacteria are threatening modern health care. However, estimating their incidence, complications, and attributable mortality is challenging.
Abu Sin, Muna   +79 more
core   +6 more sources

In-vitro evaluation of different antimicrobial combinations with and without colistin against carbapenem-resistant acinetobacter baumannii [PDF]

open access: yes, 2019
Carbapenem-resistant Acinetobacter baumannii (CR-Ab) infections are associated with high morbidity and mortality. The aim of the study was to evaluate the in-vitro activity of different antimicrobial combinations (with and without colistin, COL) against ...
De Angelis, Massimiliano   +6 more
core   +1 more source

Influence of different antibiotic groups on the development of mutational resistance to colistin among Klebsiella pneumoniae [PDF]

open access: yesКлиническая микробиология и антимикробная химиотерапия, 2021
Objective. To determine the concentration of colistin, preventing the selection of colistin-resistant mutants of K. pneumoniae, and to evaluate the effect of antibiotics of different groups on the development of mutational resistance to colistin ...
Petrovskaya T.A., Tapalskiy D.V.
doaj   +1 more source

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