Results 41 to 50 of about 15,930 (153)

Role of efflux pumps, their inhibitors, and regulators in colistin resistance

open access: yesFrontiers in Microbiology, 2023
Colistin is highly promising against multidrug-resistant and extensively drug-resistant bacteria clinically. Bacteria are resistant to colistin mainly through mcr and chromosome-mediated lipopolysaccharide (LPS) synthesis-related locus variation. However,
Yinhuan Ding   +9 more
doaj   +1 more source

Assessment of colistin resistance in Gram negative bacteria from clinical samples in resource-limited settings

open access: yesAsian Pacific Journal of Tropical Medicine, 2022
Objective: To find a proper method to assess colistin resistance in multidrug resistant Gram negative bacteria (MDR-GNB) on a routine basis in resource limited settings. Methods: Clinical samples were processed.
Shubham Chauhan   +4 more
doaj   +1 more source

A Clinico-Microbiological Study of Blood Stream Infections in a Tertiary Referral Hospital: Colistin Resistance & Challenges

open access: yes, 2023
Carbapenems, frequently used for the treatment of infections caused by Multidrug-resistant (MDR) Gram-negative bacteria (GNB) are being reported with increased resistance rate.
Jyoti Chaudhary   +2 more
core   +1 more source

Colistin-resistance gene mcr in clinical carbapenem-resistant Enterobacteriaceae strains in China, 2014–2019

open access: yes, 2020
To investigate whether introduction of colistin into the clinical settings selected colistin-resistant CRE, we performed molecular epidemiological study of 1868 CRE strains collected from different geographical locales in China during the period 2014 ...
Rong Zhang (44942)   +7 more
core   +1 more source

Influence of different antibiotic groups on the development of mutational resistance to colistin among Klebsiella pneumoniae [PDF]

open access: yesКлиническая микробиология и антимикробная химиотерапия, 2021
Objective. To determine the concentration of colistin, preventing the selection of colistin-resistant mutants of K. pneumoniae, and to evaluate the effect of antibiotics of different groups on the development of mutational resistance to colistin ...
Petrovskaya T.A., Tapalskiy D.V.
doaj   +1 more source

The effectiveness and nephrotoxicity of loading dose colistin combined with or without meropenem for the treatment of carbapenem-resistant A. baumannii

open access: yesInternational Journal of Infectious Diseases, 2020
Introduction: Acinetobacter baumannii has emerged as an important nosocomial pathogen worldwide. In Thailand, the incidence and mortality rate of carbapenem-resistant A. baumannii (CRAB) is continuously increasing. This organism is a common pathogen that
Wasan Katip   +2 more
doaj   +1 more source

Treatment outcome and adverse effects of colistin in adult patients with carbapenem-resistant gram-negative bacteremia from Pakistan

open access: yesInternational Journal of Infectious Diseases, 2021
Background: Polymyxins (colistin) have emerged for the treatment of carbapenem resistant (CR) gram-negative infections. There is a paucity of data on treatment outcomes and adverse effects of high-dose colistin treatment in Pakistan.
Zaheer Udin Babar   +2 more
doaj   +1 more source

Safety and Efficacy of Intravenous Colistin (Colistin Methanesulphonate) for Severe Multidrug-Resistant Gram-Negative Bacterial Infections

open access: yes, 2011
Multidrug-resistant (MDR) bacterial infections are increasing in Taiwan hospitals, prompting the common use of colistin. In this study, the safety and efficacy of intravenous (i.v.) colistin was assessed.
盛望徽;王振泰;陳宜君;張上淳;   +1 more
core   +1 more source

Colistin-stimulated ROS production is significantly impaired by the presence of colistin resistance-conferring proteins (EptA/MCR-1/ICR-Mo).

open access: yes, 2018
A & B Accumulation of hydrogen peroxide is boosted by colistin stress in E. coli. C & D The presence of plasmid-borne EptA inhibits colistin-induced production of hydrogen peroxide in E. coli.
Swaminath Srinivas (450675)   +7 more
core   +1 more source

Colistin-Loaded Polydopamine Nanospheres Uniformly Decorated with Silver Nanodots: A Nanohybrid Platform with Improved Antibacterial and Antibiofilm Performance

open access: yes, 2020
Bacterial infections, especially chronic infections caused by bacterial biofilms, have become a worldwide threat to public health. Encouragingly, the synergistic actions of two or more antibacterial drugs have been proven to be effective in treating ...
Huan-Huan Ran (6630830)   +8 more
core   +1 more source

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