Results 41 to 50 of about 20,481 (152)

Impact of colistin and colistin-loaded on alginate nanoparticles on pigs infected with a colistin-resistant enterotoxigenic Escherichia coli strain

, 2022
International audienceColistin is frequently used for the control of post-weaning diarrhoea in pigs. Colistin resistance caused by plasmidic genes is a public health issue.
Drider, Djamel, Belguesmia, Yanath, Hazime, Noura, Le Devendec, Laetitia, Paboeuf, Frédéric, Boukherroub, Rabah, Mourand, Gwenaelle, Kempf, Isabelle, Rabah Boukherroub, Noura Hazime, Djamel Drider, Gwenaelle Mourand, Laetitia Le Devendec, Yanath Belguesmia, Frédéric Paboeuf, Isabelle Kempf   +15 more
core   +1 more source

Colistin

Reactions Weekly, 2015
Colistin (polymyxin E) is a positively charged deca-peptide antibiotic that disrupts the integrity of the outer membrane of the cell wall of gram-negative bacteria by binding to the lipid A moiety of lipopolysaccharides, resulting in cell death. The endotoxic activity of lipopolysaccharides is simultaneously inhibited.
Dijkmans, Anneke C., Wilms, Erik B., Kamerling, Ingrid M. C., Birkhoff, Willem, Ortiz-Zacarias, Natalia V., van Nieuwkoop, Cees, Verbrugh, Henri A., Touw, Daan J.   +7 more
  +6 more sources

Disease‐Stage Synchronized Nanozyme Therapy for Polymicrobial Sepsis through Adaptive Catalytic and Immune Reprogramming

Advanced Science, EarlyView.
A disease‐stage synchronized nanozyme platform is developed to treat polymicrobial sepsis by adapting its functions to changing infection environments. The system eliminates multidrug‐resistant bacteria during early infection while reducing inflammation and restoring immune balance during recovery, providing an integrated strategy for infection control
Anlai Zou, Xiaoxue Zhu, Runhan Zhu, Chengchu Xue, Qinyu Zhang, Mengke Li, Ting Yu, Yuzhen Gao, Zhi Ruan, Ying Fu, Yunlei Xianyu, Jun Zhang   +11 more
wiley   +1 more source

Effects of an Organic Acid Blend on Growth Performance, Redox Homeostasis, and Intestinal Microbiota of Broilers in an Antibiotic‐Free Production System Under Winter Environmental Challenges

Animal Research and One Health, EarlyView.
Schematic summary of the effects of organic acids on growth performance and gut health‐related parameters in broilers. ABSTRACT This study was conducted to evaluate the effects of an organic acid blend on growth performance, redox homeostasis, and intestinal microbiota of broilers raised in an antibiotic‐free system during the winter season in China ...
Rong‐Hui Huang, Hong‐Lin Li, Yu Zhang, Jie Wang, Shao‐Qing Wang, Xue‐Wu Li, Lane Pineda, Xiang‐Dong Kuang, Giseli Heim, Mahmoud Mohamed Khalil, Lv‐Hui Sun, Zhang‐Chao Deng   +11 more
wiley   +1 more source

Colistin Enhances Rifampicin's Antimicrobial Action in Colistin-Resistant Pseudomonas aeruginosa Biofilms

, 2023
The emergence of multidrug-resistant Pseudomonas aeruginosa infections has urged the need to find new strategies, such as the use of combinations of antibiotics. Among these, the combination of colistin with other antibiotics has been studied.
Sierra, Josep M., Høiby, Niels, Higazy, Doaa, Viñas, Miguel, Ciofu, Oana, Armengol, Eva, Tolker-Nielsen, Tim, Kragh, Kasper Nørskov   +7 more
core   +1 more source

Re-emerging of colistin for treatment of nosocomial pneumonia due to gram negative multi-drug resistant pathogens in critically ill patients

Egyptian Journal of Chest Disease and Tuberculosis, 2013
Background: Gram-negative (G-ve) bacilli, particularly Pseudomonas aeruginosa and Acinetobacter baumannii, are important opportunistic multidrug-resistant (MDR) pathogens in hospitalized patients, contributing to their morbidity and mortality.
Mohamed Amin, Alaa Rashad, Assem Fouad, Amal Abdel Azeem   +3 more
doaj   +1 more source

Serotype Is Associated With High Rate of Colistin Resistance Among Clinical Isolates of Salmonella

Frontiers in Microbiology, 2020
To investigate the prevalence, probable mechanisms and serotype correlation of colistin resistance in clinical isolates of Salmonella from patients in China, Salmonella isolates were collected from fecal and blood samples of patients. In this study, 42.8%
Qixia Luo, Yuan Wang, Hao Fu, Xiao Yu, Beiwen Zheng, Yunbo Chen, Björn Berglund, Björn Berglund, Yonghong Xiao   +8 more
doaj   +1 more source

The role of pmrCAB genes in colistin-resistant Acinetobacter baumannii

Scientific Reports, 2022
The progressively increasing antimicrobial-resistant Acinetobacter baumannii infections have enforced the use of colistin as the last option for therapy, resulting in the colistin resistance evolution. This work aimed to study the pmrCAB expression in A.
Shaimaa Mohamed Seleim, Marwa Salah Mostafa, Nadia Hafez Ouda, Rania Yahia Shash   +3 more
doaj   +1 more source

The sRNA vvrr1 Modulates the VarS/VarA‐Csr System via LeuO to Regulate Biofilm Formation and Virulence in Vibrio alginolyticus

Animal Research and One Health, EarlyView.
vvrr1, a small RNA, post‐transcriptionally represses the transcriptional regulator LeuO, which directly inhibits the VarS/VarA two‐component system. This triggers a Csr cascade that relieves LuxO repression, ultimately modulating exopolysaccharide production to control biofilm formation and virulence in Vibrio alginolyticus.
Theerakamol Pengsakul, Lei Wen, Lingmin Zhao, Bei Huang, Jiang Zheng, Binfu Xu, Lixing Huang   +6 more
wiley   +1 more source

In vitro synergism of combinations of colistin with selected antibiotics against colistin-resistant Acinetobacter baumannii

, 2014
[english] Aim: The in vitro activity of colistin in combination with sulbactam, netilmicin, and vancomycin against colistin-resistant strains was investigated. Furthermore, the clonal relationship of the strains was analyzed.
Kalin, G, Akyol, Selcan, Kalin, Gamze, Percin, Duygu, Percin, D, Akyol, S   +5 more
core   +1 more source