Results 51 to 60 of about 15,930 (153)

Serotype Is Associated With High Rate of Colistin Resistance Among Clinical Isolates of Salmonella

Frontiers in Microbiology, 2020
To investigate the prevalence, probable mechanisms and serotype correlation of colistin resistance in clinical isolates of Salmonella from patients in China, Salmonella isolates were collected from fecal and blood samples of patients. In this study, 42.8%
Qixia Luo, Yuan Wang, Hao Fu, Xiao Yu, Beiwen Zheng, Yunbo Chen, Björn Berglund, Björn Berglund, Yonghong Xiao   +8 more
doaj   +1 more source

Development and validation of a high-performance liquid chromatography-fluorescence detection method for the accurate quantification of colistin in human plasma

, 2017
Recently, colistin has become one of the most important drugs for treating infections caused by multidrug-resistant Gram-negative bacteria. Therapeutic drug monitoring is recommended to ensure the safety and efficacy of colistin and to improve clinical ...
郭錦樺;孫幸筠;林淑文, Chepyala, Divyabharathi;Tsai, I-Lin;Sun, Hsin-Yun;Lin, Shu-Wen;Kuo, Ching-Hua   +1 more
core   +1 more source

Synergistic activity of colistin with azidothymidine against colistin-resistant Klebsiella pneumoniae clinical isolates collected from inpatients in Greek hospitals. [PDF]

, 2019
BACKGROUND: New antibiotics are urgently needed for the treatment of multidrug resistant infections. However, the production of novel antibiotics is diminishing.
Tryfinopoulou, K, Hu, Y, Colistin - Azidothymidine Hellenic Study Group, Voulgaris, GL, Kyriakidou, M, Vatopoulos, A, Falagas, ME, Giakkoupi, P, Coates, A   +8 more
core   +1 more source

Equisetin Restores Colistin Sensitivity against Multi-Drug Resistant Gram-Negative Bacteria

Antibiotics, 2021
The overuse of antibiotics and the scarcity of new drugs have led to a serious antimicrobial resistance crisis, especially for multi-drug resistant (MDR) Gram-negative bacteria. In the present study, we investigated the antimicrobial activity of a marine
Qi Zhang, Shang Chen, Xiaojia Liu, Wenhan Lin, Kui Zhu   +4 more
doaj   +1 more source

Re-emerging of colistin for treatment of nosocomial pneumonia due to gram negative multi-drug resistant pathogens in critically ill patients

Egyptian Journal of Chest Disease and Tuberculosis, 2013
Background: Gram-negative (G-ve) bacilli, particularly Pseudomonas aeruginosa and Acinetobacter baumannii, are important opportunistic multidrug-resistant (MDR) pathogens in hospitalized patients, contributing to their morbidity and mortality.
Mohamed Amin, Alaa Rashad, Assem Fouad, Amal Abdel Azeem   +3 more
doaj   +1 more source

The role of pmrCAB genes in colistin-resistant Acinetobacter baumannii

Scientific Reports, 2022
The progressively increasing antimicrobial-resistant Acinetobacter baumannii infections have enforced the use of colistin as the last option for therapy, resulting in the colistin resistance evolution. This work aimed to study the pmrCAB expression in A.
Shaimaa Mohamed Seleim, Marwa Salah Mostafa, Nadia Hafez Ouda, Rania Yahia Shash   +3 more
doaj   +1 more source

Reversible Nephrotoxicity of Colistin: A Case Report

, 2019
Both nosocomial and community acquired gram-negative bacterial infections cause serious morbidity and mortality. However, old antibiotics, which have toxic side effects, should be re-used because of the lack of newly developed antibiotics.
Güle Çınar, İrem Akdemir Kalkan, Kemal Osman Memikoğlu   +2 more
core   +1 more source

Prevalence and transmission risk of colistin and multidrug resistance in long-distance coastal aquaculture

, 2023
Due to the wide use of antibiotics, intensive aquaculture farms have been recognized as a significant reservoir of antibiotic resistomes. Although the prevalence of colistin resistance genes and multidrug-resistant bacteria (MDRB) has been documented ...
Zhao, Huijun, An, Taicheng, Wong, Po Keung, Cai, Yiwei, Li, Shaoting, Guo, Jianhua, Li, Guiying   +6 more
core   +1 more source

Streptavidins Coordinate Biotin Sequestration and Self‐Resistance Within a Biotin‐Pathway Antibiotic Network

Advanced Science, EarlyView.
A conserved genomic region between two streptavidin genes in Streptomyces packages biosynthetic gene clusters for diverse biotin‐pathway antibiotics: acidomycin, stravidin, the new non‐proteinogenic amino acid ANDA, and the new BioA inhibitor α‐methyl‐KAPA.
Sumire Kurosawa, Jingjun Mo, Xiaotong Diao, Feng Xie, Tingting Wang, Haowen Zhao, Dalei Wu, Rolf Müller, Chengzhang Fu   +8 more
wiley   +1 more source

Development of colistin resistance via heteroresistance modeling in : A diagnostic study [PDF]

Precision and Future Medicine
Purpose Colistin heteroresistance mediates the failure of antibiotic treatments, is prone to lead to colistin resistance, and has been frequently reported in Klebsiella pneumoniae.
Jungyu Seo, Kwan Soo Ko
doaj   +1 more source