Results 71 to 80 of about 40,207 (173)

Outer membrane permeability of mcr-positive bacteria reveals potent synergy of colistin and macromolecular antibiotics against colistin-resistant Acinetobacter baumannii

Frontiers in Microbiology
Colistin (CT) is the last-resort of antibiotic against multidrug-resistance (MDR) Acinetobacter baumannii (A. baumannii) infection. However, colistin resistance is increasingly reported in A.
Meisong Li, Furong Ma, Hui Zhao, Dianrong Zhou, Dianrong Zhou, Dianrong Zhou, Lujie Liang, Lujie Liang, Lujie Liang, Runling Lv, Jiachen Li, Jiachen Li, Jiachen Li, Yaxuan Wang, Yaxuan Wang, Yaxuan Wang, Lin Xu, Lin Xu, Lin Xu, Chenfei Liu, Guo-Bao Tian, Guo-Bao Tian, Guo-Bao Tian, Siyuan Feng, Siyuan Feng, Siyuan Feng, Yong Xia   +26 more
doaj   +1 more source

Colistin Use in Patients with Extreme Renal Function: From Dialysis to Augmented Clearance

Medicina, 2019
Background and objectives: Colistin is used for the treatment of multidrug-resistant (MDR) Gram-negative bacteria infection in critically ill patients. It is recommended to adjust the dose in cases of renal impairment but not in cases of augmented renal ...
Aleksandra Aitullina, Angelika Krūmiņa, Šimons Svirskis, Santa Purviņa   +3 more
doaj   +1 more source

Vibrio Community Structure Shapes the Diversity of Carbenicillin‐Hydrolysing Class A β‐Lactamase Circulating in European Coastal Environments

Environmental Microbiology, Volume 28, Issue 8, August 2026.
Vibrio communities shape carbenicillinase diversity in European coasts. Sediments serve as reservoirs of antibiotic‐resistant Vibrio alginolyticus, which can move into the water column and accumulate in bivalves. This spreads β‐lactamase resistance and raises human exposure risks to antibiotic‐resistant pathogenic Vibrio, especially as higher seawater ...
Berenice Reggiardo, Jamal Saad, Marie‐Agnès Travers, Yannick Labreuche, David Goudenège, Eve Toulza, Coralie Broquard, Karl B. Andree, Julia Mougin, Nicolas Argenta, Gaëlle Courtay, Juliette Pouzadoux, Océane Romatif, Audrey Caro, Dolors Furones, Luigi Vezzulli, Gianluca Corno, Andrea Di Cesare, Ignasi Gairin, Bruno Petton, K. Mathias Wegner, Caroline Montagnani, Viviane Boulo, Delphine Destoumieux‐Garzón   +23 more
wiley   +1 more source

Antimicrobial Resistance of Serratia marcescens Recovered From Aquatic Environments: A Review

Environmental Microbiology Reports, Volume 18, Issue 4, August 2026.
Serratia marcescens is a gram‐negative bacillus forming biofilms and showing multidrug resistance. Review (2019–2024) included 13 studies, 90 aquatic isolates. High resistance to β‐lactams, including carbapenems. Genes: blaOXA‐48, blaTEM‐1, aac(6′)‐Ic. Aquatic environments are reservoirs, requiring monitoring and control to prevent spread.
Heloisa Silva Inacio, Yasmim Raffaela Soares Santos, Magna Cristina de Paiva, Jaqueline Maria Siqueira Ferreira   +3 more
wiley   +1 more source

Fungicide Drives De Novo Evolution of Multidrug Resistance in the Plant Growth Promoting Rhizobacterium, Pseudomonas fluorescens

Evolutionary Applications, Volume 19, Issue 8, August 2026.
ABSTRACT Soil microbial communities underpin key ecosystem processes, including plant health, nutrient cycling and primary productivity. In agricultural soils, beneficial soil bacteria are often exposed to multiple stressors simultaneously, including fungicides, antibiotics, and warming temperatures. Despite their ecological importance, little is known
Matthew Kelbrick, James P. J. Hall, Siobhán O'Brien   +2 more
wiley   +1 more source

Comparative effectiveness and mortality of colistin monotherapy versus colistin-fosfomycin combination therapy for the treatment of carbapenem-resistant Enterobacteriaceae (CRE) infections: A propensity score analysis

Journal of Infection and Public Health
Background: Carbapenem-resistant Enterobacteriaceae (CRE) infections pose a significant threat to global health due to limited treatment options and high mortality rates.
Wasan Katip, Ajaree Rayanakorn, Peninnah Oberdorfer, Puntapong Taruangsri, Teerapong Nampuan, Siriporn Okonogi   +5 more
doaj   +1 more source

β,β-Dimethylacrylalkannin Restores Colistin Efficacy Against mcr- and TCS-Mediated Resistant Gram-Negative Bacteria via Membrane Disturbance

Antibiotics
Background: The reintroduction of colistin has led to the rapid emergence of colistin-resistant strains, significantly diminishing its therapeutic efficacy. This presents a need for effective adjuvants to restore colistin efficacy.
Yongqing Liu, Huangwei Song, Muchen Zhang, Junyao Jiang, Yan Zhang, Jian Xu, Xi Xia, Shangshang Qin, Jianzhong Shen, Yang Wang, Dejun Liu   +10 more
doaj   +1 more source

Nitroxoline as an antimicrobial synergist reverses colistin resistance in multidrug-resistant Escherichia coli

iScience
Summary: Colistin is a crucial drug for treating multidrug-resistant (MDR) Escherichia coli infections. The emergence and bacterial transmission of the colistin-resistant gene mcr-1 have substantially diminished its therapeutic efficacy.
Hao Wang, Jie He, Hao Li, Chengming Li, Muhammad Inam, Jianfeng Wang, Huifeng Dong, Dingkuo Liu, Fang Liu, Jingrui Chen, Yu Jia, Yunhang Gao, Lingcong Kong, Hongxia Ma   +13 more
doaj   +1 more source

Alteration in the Morphological and Transcriptomic Profiles of Acinetobacter baumannii after Exposure to Colistin

Microorganisms
Acinetobacter baumannii is often highly resistant to multiple antimicrobials, posing a risk of treatment failure, and colistin is a “last resort” for treatment of the bacterial infection. However, colistin resistance is easily developed when the bacteria
Eun-Jeong Yoon, Jun Won Mo, Jee-woong Kim, Min Chul Jeong, Jung Sik Yoo   +4 more
doaj   +1 more source

Characterization Of Chromosome-Mediated Colistin Resistance In Escherichia coli Isolates From Livestock In Korea

Infection and Drug Resistance, 2019
Shukho Kim,1 Jung Hwa Woo,1 Nayeong Kim,1 Mi Hyun Kim,1 Se Yeon Kim,1 Joo Hee Son,1 Dong Chan Moon,2 Suk-Kyung Lim,2 Minsang Shin,1 Je Chul Lee1 1Department of Microbiology, School of Medicine, Kyungpook National University, Daegu, Republic of Korea ...
Kim S, Woo JH, Kim N, Kim MH, Kim SY, Son JH, Moon DC, Lim SK, Shin M, Lee JC   +9 more
doaj