Klebsiella pneumoniae is able to trigger epithelial-mesenchymal transition process in cultured airway epithelial cells [PDF]
The ability of some bacterial pathogens to activate Epithelial-Mesenchymal Transition normally is a consequence of the persistence of a local chronic inflammatory response or depends on a direct interaction of the pathogens with the host epithelial cells.
A García-Fernández +46 more
core +2 more sources
A Genomic Catalog of Migratory Microbiomes from Wild Birds across China's Habitats
ABSTRACT Migratory birds play an important role in the spread of antimicrobial resistance (AMR); however, gaps in surveillance data from vital regions along migratory flyways across China limit the detection of emergent threats. Here, we assembled 340 metagenomes from 52 bird species covering 11 provincial administrative districts in China, presenting ...
Yanan Wang +13 more
wiley +1 more source
Global burden of colistin-resistant bacteria : mobilized colistin resistance genes study (1980-2018) [PDF]
Colistin is considered to be an antimicrobial of last-resort for the treatment of multidrug-resistant Gram-negative bacterial infections. The recent global dissemination of mobilized colistin resistance (mcr) genes is an urgent public health threat.
Elbediwi, Mohammed +10 more
core +1 more source
ABSTRACT Background and Aims The Gaza Strip has faced prolonged blockade, recurrent military conflicts, and systemic infrastructure collapse since October 2023, resulting in an unprecedented public health crisis characterized by surging infectious diseases and antimicrobial resistance (AMR).
Nima Farhadi +2 more
wiley +1 more source
Infections by multidrug-resistant Gram-negative bacteria are increasingly common, prompting the renewed interest in the use of colistin. Colistin specifically targets Gram-negative bacteria by interacting with the anionic lipid A moieties of ...
Axel B. Janssen +6 more
doaj +1 more source
Safety and efficacy of colistin versus meropenem in the empirical treatment of ventilator-associated pneumonia as part of a macro-project funded by the Seventh Framework Program of the European Commission studying off-patent antibiotics. study protocol for a randomized controlled trial [PDF]
Background: Ventilator-associated pneumonia (VAP) is one of the most common and severe hospital-adquired infections, and multidrugresistant gram-negative bacilli (MDR-GNB) constitute the main etiology in many countries.
Clara Rosso, Fernández +6 more
core +1 more source
ABSTRACT Background and Aims Pseudomonas aeruginosa is a non‐fermentative, opportunistic Gram‐negative bacterium that causes 10%–15% of nosocomial and burn wound infections worldwide. This bacterium is resistant to various antibiotics through multiple mechanisms, including acquisition of resistance genes.
Milad Gholampour Matin +4 more
wiley +1 more source
Genomic characterization of antibiotic resistant Escherichia coli isolated from domestic chickens in Pakistan [PDF]
Poultry husbandry is important for the economic health of Pakistan, but the Pakistani poultry industry is negatively impacted by infections ...
Abbas, Muhammad Athar +11 more
core +1 more source
Draft Genome Sequence of an International Clonal Lineage 1 Acinetobacter baumannii Strain from Argentina [PDF]
In the last few years Acinetobacter baumannii has emerged worldwide as an important nosocomial pathogen in medical institutions. Here, we present the draft genome sequence of the international clonal lineage 1 (ICL1) A.
Centron, Daniela +5 more
core +1 more source
Tibetan pig farms host diverse Escherichia coli strains that resist multiple antibiotics and carry important disease genes, such as astA. These traits jump easily between bacterial groups, marking intensive pig production as a key reservoir and signalling the need for integrated animal–human surveillance and more careful antibiotic use.
Runbo Luo +7 more
wiley +1 more source

