Results 81 to 90 of about 20,481 (152)
ABSTRACT Inter‐individual variability in drug exposure can lead to ineffective therapy or toxicity, particularly in vulnerable patients. Routine model‐informed precision dosing (MIPD) relies mainly on population pharmacokinetic (PopPK) models, Bayesian forecasting, and therapeutic drug monitoring (TDM).
Yunmeng Pang +5 more
wiley +1 more source
ABSTRACT Salmonella enterica remains a major foodborne pathogen in poultry‐processing environments, where its persistence is largely attributed to biofilm formation on food‐contact and non‐food‐contact surfaces. Despite extensive research on Salmonella control, persistent contamination continues to challenge food safety due to the complex interplay ...
Md Anamul Hasan Chowdhury +4 more
wiley +1 more source
Serum bactericidal activity of colistin and azidothymidine combinations against mcr-1 positive colistin-resistant Escherichia coli. [PDF]
To examine the serum bactericidal activity of colistin-sulphate (CS) and azidothymidine (AZT) combinations, time-kill curves were performed in native and heat-inactivated human serum with five colistin-resistant and four colistin-susceptible Gram ...
Loose, M +4 more
core +1 more source
Molecular mechanisms related to colistin resistance in Enterobacteriaceae
Zahra Aghapour,1,2 Pourya Gholizadeh,3 Khudaverdi Ganbarov,4 Abed Zahedi Bialvaei,5 Suhad Saad Mahmood,6 Asghar Tanomand,7 Mehdi Yousefi,8 Mohammad Asgharzadeh,9 Bahman Yousefi,9 Hossein Samadi Kafil11Drug Applied Research Center, Tabriz University of ...
Ganbarov K +9 more
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Recently, colistin has become one of the most important drugs for treating infections caused by multidrug-resistant Gram-negative bacteria. Therapeutic drug monitoring is recommended to ensure the safety and efficacy of colistin and to improve clinical ...
郭錦樺;孫幸筠;林淑文 +1 more
core +1 more source
Colistin Use in Patients with Extreme Renal Function: From Dialysis to Augmented Clearance
Background and objectives: Colistin is used for the treatment of multidrug-resistant (MDR) Gram-negative bacteria infection in critically ill patients. It is recommended to adjust the dose in cases of renal impairment but not in cases of augmented renal ...
Aleksandra Aitullina +3 more
doaj +1 more source
© 2018, © 2018 Edizioni Scientifiche per l'Informazione su Farmaci e Terapia.The aim of the study is to determine in-vitro effects of imipenem–tigecycline, imipenem–colistin and tigecycline–colistin against carbapenem-resistant Enterobacteriaceae (CRE ...
DÜNDAR, DEVRİM +5 more
core +1 more source
Gelofusine ameliorates colistin-induced nephrotoxicity [PDF]
Colistin therapy is used as the last line of defense against life-threatening Gram-negative infections. Nephrotoxicity is the major dose-limiting side effect that impedes optimal dosing of patients.
Sivanesan, Sivashangarie S. +17 more
core +1 more source
There is a critical need for treatment strategies to combat carbapenem-resistant Gram-negative pathogens. This study investigates the efficacy of combining low concentrations of colistin with tigecycline against colistin- and carbapenem-resistant ...
Suyeon Park, Yanhong Jin, Kwan Soo Ko
doaj +1 more source
Colistin resistance in clinically important Enterobacteriaceae [PDF]
Colistin is a last-resort antibiotic used to treat serious infections caused by Enterobacteriaceae and other multidrug resistant gram-negative bacteria.
Smělíková, Eva
core

