Results 101 to 110 of about 15,930 (153)

Molecular evaluation of colistin-resistant gene expression changes in Acinetobacter baumannii with real-time polymerase chain reaction

, 2017
Shahriar Sepahvand,1 Mohammad Ali Davarpanah,2 Amir Roudgari,3 Abbas Bahador,4 Vajihe Karbasizade,5 Zahra Kargar Jahromi6 1Department of Microbiology, Falavarjan Branch, Islamic Azad University, Isfahan, Iran; 2Shiraz HIV/AIDS Research Center, Institute ...
Roudgari A, Sepahvand S, Kargar Jahromi Z, Davarpanah MA, Bahador A, Karbasizade V   +5 more
core  

Gelofusine ameliorates colistin-induced nephrotoxicity

, 2017
Colistin therapy is used as the last line of defense against life-threatening Gram-negative infections. Nephrotoxicity is the major dose-limiting side effect that impedes optimal dosing of patients.
Sivanesan, Sivashangarie S., Nation, Roger L., Wang, Jiping, Azad, Mohammad A. K., Ahmed, Maizbha U., Schneider, Elena K., Li, Jian, Huang, Jiayuan, Velkov, Tony   +8 more
core   +2 more sources

Frequency of colistin and fosfomycin resistance in carbapenem-resistant Enterobacteriaceae from a tertiary care hospital in Karachi

, 2017
Salima Qamar, Najma Shaheen, Sadia Shakoor, Joveria Farooqi, Kauser Jabeen, Rumina Hasan Clinical Microbiology, Department of Pathology And Laboratory Medicine, Aga Khan University Hospital, Karachi, Pakistan Introduction ...
Farooqi J, Hasan R, Jabeen K, Shakoor S, Qamar S, Shaheen N   +5 more
core  

Nitroxoline as an antimicrobial synergist reverses colistin resistance in multidrug-resistant Escherichia coli

iScience
Summary: Colistin is a crucial drug for treating multidrug-resistant (MDR) Escherichia coli infections. The emergence and bacterial transmission of the colistin-resistant gene mcr-1 have substantially diminished its therapeutic efficacy.
Hao Wang, Jie He, Hao Li, Chengming Li, Muhammad Inam, Jianfeng Wang, Huifeng Dong, Dingkuo Liu, Fang Liu, Jingrui Chen, Yu Jia, Yunhang Gao, Lingcong Kong, Hongxia Ma   +13 more
doaj   +1 more source

Effectiveness of treatment with nebulized colistin in patients with COPD

, 2017
Nuria Bruguera-Avila,1–3 Alicia Marin,3–5 Ignasi Garcia-Olive,3–5 Joaquim Radua,6–8 Cristina Prat,4,9,10 Montserrat Gil,3 Juan Ruiz-Manzano2–5 1Department of Medicine, Hospital Sant Jaume de Calella, Calella, Barcelona ...
Garcia-Olive I, Radua J, Bruguera-Avila N, Marín A, Ruiz-Manzano J, Gil M, Prat C   +6 more
core  

Comparative effectiveness and mortality of colistin monotherapy versus colistin-fosfomycin combination therapy for the treatment of carbapenem-resistant Enterobacteriaceae (CRE) infections: A propensity score analysis

Journal of Infection and Public Health
Background: Carbapenem-resistant Enterobacteriaceae (CRE) infections pose a significant threat to global health due to limited treatment options and high mortality rates.
Wasan Katip, Ajaree Rayanakorn, Peninnah Oberdorfer, Puntapong Taruangsri, Teerapong Nampuan, Siriporn Okonogi   +5 more
doaj   +1 more source

Transcriptomic analysis of colistin-susceptible and colistin-resistant isolates identifies genes associated with colistin resistance in Acinetobacter baumannii

, 2015
The emergence of colistin-resistant Acinetobacter baumannii is concerning, as colistin is often regarded as the last option for treating multidrug-resistant (MDR) A. baumannii infections.
Ko, K.S., Park, Y.K., Lee, J.-Y.
core   +1 more source

Resistance to Colistin Mediated by mcr-1 among Multidrug Resistant Gram Negative Pathogens at a Tertiary Care Hospital, Egypt

, 2020
Colistin is considered the last option for treatment of infections caused by Multidrug Resistant (MDR) Gram negative pathogens. The mcr-1 gene could transfer the resistance to colistin between different species.
Noha Alaa Eldin Fahim, Nagwa M Abo El Magd, Nagwa M. Abo El Magd, Marwa Shabban, Karim Montasser   +4 more
core   +1 more source

Inhalation with intravenous loading dose of colistin in critically ill patients with pneumonia caused by carbapenem-resistant gram-negative bacteria

Therapeutic Advances in Respiratory Disease, 2019
Background: Despite the increasing use of colistin in clinical practice, the optimal dosing, and administration route have not been established. This study aimed to evaluate the clinical outcome and safety of intravenous (IV) colistin with a loading dose
Junsu Choe, You Min Sohn, Suk Hyeon Jeong, Hyo Jung Park, Soo Jin Na, Kyungmin Huh, Gee Young Suh, Kyeongman Jeon   +7 more
doaj   +1 more source

Alteration in the Morphological and Transcriptomic Profiles of Acinetobacter baumannii after Exposure to Colistin

Microorganisms
Acinetobacter baumannii is often highly resistant to multiple antimicrobials, posing a risk of treatment failure, and colistin is a “last resort” for treatment of the bacterial infection. However, colistin resistance is easily developed when the bacteria
Eun-Jeong Yoon, Jun Won Mo, Jee-woong Kim, Min Chul Jeong, Jung Sik Yoo   +4 more
doaj   +1 more source