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Colistin use and colistin resistance in bacteria from animals

International Journal of Antimicrobial Agents, 2016
Colistin has been used in veterinary medicine for decades, mainly for the prevention and treatment of Enterobacteriaceae infections. However, data regarding colistin resistance in bacteria from animals and food of animal origin are relatively scarce, partly because there are methodological difficulties hampering the analysis of susceptibility to ...
Isabelle Kempf, Eric Jouy
exaly   +3 more sources

Colistin, mechanisms and prevalence of resistance

Current Medical Research and Opinion, 2015
Infections caused by multi-drug-resistant Gram-negative bacteria, particularly Acinetobacter baumannii, Pseudomonas aeruginosa and Klebsiella pneumoniae, that cause nosocomial infections, represent a growing problem worldwide. The rapid increase in the prevalence of Gram-negative pathogens that are resistant to fluoroquinolones and aminoglycosides as ...
Hossein Samadi Kafil   +1 more
exaly   +3 more sources

The History of Colistin Resistance Mechanisms in Bacteria: Progress and Challenges

open access: yesMicroorganisms, 2021
International audienceSince 2015, the discovery of colistin resistance genes has been limited to the characterization of new mobile colistin resistance (mcr) gene variants. However, given the complexity of the mechanisms involved, there are many colistin-
Jean-Marc Rolain, Mouna Hamel
exaly   +2 more sources

Colistin Update on Its Mechanism of Action and Resistance, Present and Future Challenges

open access: yesMicroorganisms, 2020
Colistin has been extensively used since the middle of the last century in animals, particularly in swine, for the control of enteric infections. Colistin is presently considered the last line of defense against human infections caused by multidrug ...
Cidália Pina-Vaz, Ferdinando F Andrade
exaly   +2 more sources

Colistin resistance in Klebsiella pneumoniae

International Journal of Antimicrobial Agents, 2014
Increasing use of colistin for multidrug-resistant Gram-negative bacterial infections has led to the emergence of colistin resistance in Klebsiella pneumoniae in several countries worldwide, including Europe (especially Greece), and colistin resistance rates are continually increasing.
Young-Mi, Ah, Ah-Jung, Kim, Ju-Yeun, Lee
openaire   +2 more sources

Genomic characterization of colistin resistance in Klebsiella spp. under the pressure of colistin

Journal of Medical Microbiology, 2023
Introduction. Carbapenem-resistant Klebsiella pneumoniae (CRKP) has become a serious threat to global public health. Colistin is regarded as the last-resort antibiotic for CRKP infections, but colistin resistance among CRKP is increasingly being ...
Xin, Chen   +4 more
openaire   +2 more sources

Performance evaluation of colistin rapid NP test for detection of colistin resistance in colistin resistant Enterobacterales

Medical Journal Armed Forces India
Carbapenem-resistant Enterobacterales (CRE) have become a global threat, with colistin being the last resort for treatment. CLSI and EUCAST recommend broth microdilution (BMD) as the reference method for colistin susceptibility testing. Nordmann and Poirel have developed a simple and rapid Polymyxin NP test as an alternative to BMD for screening of ...
Punyatoya Kar   +4 more
openaire   +2 more sources

Plasmid-mediated colistin resistance: the final blow to colistin?

International Journal of Antimicrobial Agents, 2016
no ...
Rolain, Jean-Marc   +1 more
openaire   +3 more sources

RETRACTED: Verapamil increases susceptibility of colistin-resistant Acinetobacter baumannii to colistin

International Journal of Antimicrobial Agents
Acinetobacter baumannii, which is predominantly responsible for hospital-acquired infections, presents a tremendous clinical challenge due to its increasing antibiotic resistance to colistin (COL), a last-line antibiotic. As a result, the combination of antimicrobial and non-antimicrobial agents is emerging as a more popular treatment approach against ...
Sichen, Liu   +9 more
openaire   +2 more sources

[Effect of colistin consumption and prevalence of colistin-resistant bacteria].

Klinicka mikrobiologie a infekcni lekarstvi, 2015
Recently, there has been a renaissance of the use of the antibiotic colistin resulting from increasing resistance of bacterial pathogens, particularly in intensive care patients. The study aimed at assessing the impact of colistin consumption on the prevalence of colistin-resistant bacteria in the University Hospital Olomouc (UHO).A laboratory database
Vojtěch, Hanulík   +6 more
openaire   +1 more source

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