Results 201 to 210 of about 57,221 (225)

Towards Understanding MCR-like Colistin Resistance

Trends in Microbiology, 2018
Antibiotic resistance has become a global public health priority. Polymyxins, a family of cationic polypeptide antibiotics, act as a final line of refuge against severe infections by Gram-negative pathogens with pan-drug resistance. Unfortunately, this last-resort antibiotic has been challenged by the emergence and global spread of mobilized colistin ...
Jian, Sun, Huimin, Zhang, Ya-Hong, Liu, Youjun, Feng   +3 more
openaire   +4 more sources

Colistin, mechanisms and prevalence of resistance

Current Medical Research and Opinion, 2015
Infections caused by multi-drug-resistant Gram-negative bacteria, particularly Acinetobacter baumannii, Pseudomonas aeruginosa and Klebsiella pneumoniae, that cause nosocomial infections, represent a growing problem worldwide. The rapid increase in the prevalence of Gram-negative pathogens that are resistant to fluoroquinolones and aminoglycosides as ...
Abed Zahedi, Bialvaei, Hossein, Samadi Kafil   +1 more
openaire   +4 more sources

Plasmid-mediated colistin-resistance genes: mcr

Trends in Microbiology
Colistin is regarded as a last-line drug against serious infections caused by multidrug-resistant Gram-negative bacterial pathogens. Therefore, the emergence of mobile colistin resistance (mcr) genes has attracted global concern and led to policy changes for the use of colistin in food animals across many countries.
Jian-Hua Liu, Yi-Yun Liu, Ying-Bo Shen, Jun Yang, Timothy R. Walsh, Yang Wang, Jianzhong Shen   +6 more
openaire   +4 more sources

Performance evaluation of colistin rapid NP test for detection of colistin resistance in colistin resistant Enterobacterales

Medical Journal Armed Forces India
Carbapenem-resistant Enterobacterales (CRE) have become a global threat, with colistin being the last resort for treatment. CLSI and EUCAST recommend broth microdilution (BMD) as the reference method for colistin susceptibility testing. Nordmann and Poirel have developed a simple and rapid Polymyxin NP test as an alternative to BMD for screening of ...
Punyatoya Kar, Bijayini Behera, Srujana Mohanty, Jayanti Jena, Ashoka Mahapatra   +4 more
openaire   +2 more sources

The surveillance of colistin resistance and mobilized colistin resistance genes in multidrug-resistant Enterobacteriaceae isolated in Japan

International Journal of Antimicrobial Agents, 2022
The plasmid-mediated bacterial colistin-resistant gene, mcr, is of global concern in clinical healthcare. However, there are few reports of surveillance for mcr in Japan. The aim of this study was to assess the prevalence of colistin resistance by identifying nine mcr genes in extended-spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae and ...
Yasuhide Kawamoto, Norihito Kaku, Norihiko Akamatsu, Kei Sakamoto, Kosuke Kosai, Yoshitomo Morinaga, Norio Ohmagari, Koichi Izumikawa, Yoshihiro Yamamoto, Hiroshige Mikamo, Mitsuo Kaku, Kazunori Oishi, Katsunori Yanagihara   +12 more
openaire   +2 more sources

Plasmid-mediated colistin resistance: the final blow to colistin?

International Journal of Antimicrobial Agents, 2016
no ...
Rolain, Jean-Marc, Olaitan, Abiola Olumuyiwa   +1 more
openaire   +3 more sources

RETRACTED: Verapamil increases susceptibility of colistin-resistant Acinetobacter baumannii to colistin

International Journal of Antimicrobial Agents
Acinetobacter baumannii, which is predominantly responsible for hospital-acquired infections, presents a tremendous clinical challenge due to its increasing antibiotic resistance to colistin (COL), a last-line antibiotic. As a result, the combination of antimicrobial and non-antimicrobial agents is emerging as a more popular treatment approach against ...
Sichen, Liu, Huijing, Zhou, Jingchun, Kong, Huanchang, Chen, Lei, Chen, Miran, Tang, Beibei, Zhou, Mengxin, Xu, Lijiang, Chen, Tieli, Zhou   +9 more
openaire   +2 more sources

Global Burden of Colistin Resistant Bacteria: Mobilized Colistin Resistant Genes Study 1980-2018

SSRN Electronic Journal, 2018
Background: Global dissemination of the mobilized colistin resistance (mcr) genes provokes a significant public health threat. However, the exact global prevalence of mcr genes, their reservoirs and the potential transmission pathways to humans have not been comprehensively examined.   Methods: Bilingual publications in four English (PubMed, Scopus,
Mohammed Elbediwi, Yan Li, Narayan Paudyal, Hang Pan, Xiaoliang Li, Shaohua Xie, Andreja Rajkovic, Youjun Feng, Weihuan Fang, Min Yue   +9 more
openaire   +1 more source

Colistin resistance

2020
Indranil Samanta, Samiran Bandyopadhyay
openaire   +1 more source

Colistin resistance in Carbapenem-resistant Klebsiella pneumoniae strains.

2016
Objective: Because of the increase in the infections caused by carbapenem-resistant Klebsiella pneumoniae carbapenemase (KPC)-producing K. pneumoniae; nowadays colistin is used more frequently. In this study, the firstly detected colistin resistance in carbapenem-resistant KPC-producing K. pneumoniae strains were evaluated.
Kalem F., Ergun A.G., Ertuğrul Ö., Özçimen S., Şimşek H., Süzük S., Ünaldı Ö.   +6 more
openaire   +2 more sources