Results 111 to 120 of about 97,018 (264)

Diagnosis and Severity Assessment of Ulcerative Colitis using Self Supervised Learning [PDF]

open access: yesarXiv
Ulcerative Colitis (UC) is an incurable inflammatory bowel disease that leads to ulcers along the large intestine and rectum. The increase in the prevalence of UC coupled with gastrointestinal physician shortages stresses the healthcare system and limits the care UC patients receive.
arxiv  

A Bottom-up Approach to Testing Hypotheses That Have a Branching Tree Dependence Structure, with False Discovery Rate Control [PDF]

open access: yesarXiv, 2019
Modern statistical analyses often involve testing large numbers of hypotheses. In many situations, these hypotheses may have an underlying tree structure that not only helps determine the order that tests should be conducted but also imposes a dependency between tests that must be accounted for. Our motivating example comes from testing the association
arxiv  

Palladium Nanoparticles Degrade Advanced Glycation End Products via Valosin‐Containing Protein Mediated Autophagy to Attenuate High‐Glucose/High‐Fat‐Induced Intervertebral Disc Degeneration

open access: yesExploration, EarlyView.
Illustration of Pd NP‐mediated rescue of HGHF (or advanced glycation end products [AGEs])‐induced IVD degeneration by targeting AGEs degradation. Pd NPs promote the ATPase activity of VCP and upregulate autophagosome formation to degrade AGEs. Consequently, Pd NPs alleviate the oxidative and ER stress, protect the structure and function of mitochondria,
Xiao Yang   +13 more
wiley   +1 more source

Race, age, and sex differences on the influence of obesity on colorectal cancer sidedness and mortality: A national cross‐sectional study

open access: yesJournal of Surgical Oncology, Volume 127, Issue 1, Page 109-118, January 2023., 2023
Abstract Background and Objectives Colorectal cancer (CRC) sidedness is recognized as a prognostic factor for survival; left‐sided colorectal cancer is associated with better outcomes than right‐sided colon cancer (RsCC). We aimed to evaluate the influence of obesity on CRC sidedness and determine how race, age, and sex affect mortality among ...
Mark B. Ulanja   +9 more
wiley   +1 more source

Synthetic Biology‐Based Engineering Cells for Drug Delivery

open access: yesExploration, EarlyView.
Synthetic biology‐based therapeutic cells for drug delivery: Engineered cells effectively transport and release drugs through their intelligence and controllability, such as feedback pathways and external stimuli (e.g., light and ultrasound). The integration of nanotechnology, including nanoparticles, biofilms, and artificial cells, enhances ...
Wenzhe Yi   +4 more
wiley   +1 more source

Arges: Spatio-Temporal Transformer for Ulcerative Colitis Severity Assessment in Endoscopy Videos [PDF]

open access: yesarXiv
Accurate assessment of disease severity from endoscopy videos in ulcerative colitis (UC) is crucial for evaluating drug efficacy in clinical trials. Severity is often measured by the Mayo Endoscopic Subscore (MES) and Ulcerative Colitis Endoscopic Index of Severity (UCEIS) score. However, expert MES/UCEIS annotation is time-consuming and susceptible to
arxiv  

HLA TYPING OF ULCERATIVE COLITIS IN IRAN

open access: yesActa Medica Iranica, 1996
Ulcerative colitis is an acute or chronic inflammatory bowel disease that diffusely involves the colonic mucosa. the etiology of ulcerative colitis is unknown.
Froutan   +4 more
doaj  

EndoDINO: A Foundation Model for GI Endoscopy [PDF]

open access: yesarXiv
In this work, we present EndoDINO, a foundation model for GI endoscopy tasks that achieves strong generalizability by pre-training on a well-curated image dataset sampled from the largest known GI endoscopy video dataset in the literature. Specifically, we pre-trained ViT models with 1B, 307M, and 86M parameters using datasets ranging from 100K to 10M ...
arxiv  

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