Results 141 to 150 of about 457,403 (331)

Venous thromboembolic events in the tofacitinib ulcerative colitis clinical development programme

Alimentary Pharmacology and Therapeutics, 2019
Tofacitinib is an oral, small molecule JAK inhibitor for the treatment of ulcerative colitis (UC).
W. Sandborn, J. Panés, B. Sands, W. Reinisch, C. Su, N. Lawendy, N. Koram, H. Fan, T. Jones, I. Modesto, D. Quirk, S. Danese   +11 more
semanticscholar   +1 more source

Reoperative pouch surgery for suspected Crohn's‐related complications aided by biologic coverage: Early experience from an inflammatory bowel disease center

Annals of Gastroenterological Surgery, EarlyView.
This paper demonstrates that revisional/redo ileal pouch anal anastomosis (IPAA) surgery with concurrent biologic therapy provides a viable, stoma‐free alternative for patients with Crohn's disease‐like complications, showing a high functioning pouch rate and expanding options for managing pouch failure.
Mehmet Gulmez, Daniel J. Wong, Ariela K. Holmer, Eren Esen, Shannon Chang, Arman Erkan, David Hudesman, Andre da Luz Moreira, Feza H. Remzi   +8 more
wiley   +1 more source

HLA TYPING OF ULCERATIVE COLITIS IN IRAN

Acta Medica Iranica, 1996
Ulcerative colitis is an acute or chronic inflammatory bowel disease that diffusely involves the colonic mucosa. the etiology of ulcerative colitis is unknown.
Froutan, H., Nikbin, B. Habibabadi, M.   +4 more
doaj  

Clinical and Economic Insights Into Surgery for Colonic Diverticular Perforation: A Long‐Term Observational Cohort Study

Annals of Gastroenterological Surgery, EarlyView.
The sigmoid colon was the most common perforation site among patients with colonic diverticular perforation. The patients' conditions, length of hospital stay, and hospitalization cost were significantly worse in left‐sided colon diverticular perforation than in right‐sided colon diverticular perforation. The clinical characteristics differed according
Minoru Fujita, Noriaki Manabe, Munenori Takaoka, Masaharu Higashida, Hideo Matsumoto, Atsushi Urakami, Tomoki Yamatsuji, Tomio Ueno, Jiro Hata, Ken Haruma, Collaborators, Hisako Kubota, Jiro Hayashi, Masaki Matsubara, Takako Konishi, Emiko Bukeo, Tomohiro Tanikawa, Jun Nakamura, Mitsuhiko Suehiro, Maki Ayaki, Takahisa Murao, Kazuhiro Yoshida, Takashi Akiyama, Katsuya Kato, Hirofumi Kawamoto, Tomoari Kamada, Akiko Shiotani, Minoru Haisa, Yoshio Naomoto, Toshihiro Hirai   +29 more
wiley   +1 more source

Multiple Sampling Capsule Robot for Studying Gut Microbiome

Advanced Intelligent Systems, EarlyView.
A multiple sampling capsule robot (MSCR) is developed for longitudinal gut microbiome analysis. Employing electromagnetic field control, the MSCR can locomote actively, precisely align the selected channel, and collect up to six microbiome samples with minimal cross‐contamination.
Sanghyeon Park, Manh Cuong Hoang, Jayoung Kim, Sukho Park   +3 more
wiley   +1 more source

Hierarchical Superposition Framework Reveals the Complex Effects of Natural Medicine Formulas

Advanced Intelligent Systems, EarlyView.
A novel hierarchical superposition pharmacological model incorporates the principle of hierarchical structures from physics to simulate the spatiotemporal dynamics of drug combinations, to elucidate the universal law underlying drug combination effects. By modeling cross‐level causal transmission and attenuation, it advances beyond traditional additive
Weifeng Liang, Dingsi Xiang, Shengli Mi, Jiajun Huang   +3 more
wiley   +1 more source

Ileostomy Adenocarcinoma : a case report [PDF]

, 2004
Proctocolectomy is the standard treatment for patients suffering from ulcerative colitis which is long-standing, refractory to pharmacotherapy or otherwise associated with complications.
Abela, Joetienne, LaFerla, Godfrey, Szczepanski, Marcin J.   +2 more
core  

Characterizing the Healthcare Utilization and Costs of Hereditary Hemorrhagic Telangiectasia

American Journal of Hematology, EarlyView.
ABSTRACT Hereditary hemorrhagic telangiectasia (HHT) is the second‐most common inherited bleeding disorder worldwide, afflicting one in 4000–5000 people, and is the most morbid inherited bleeding disorder of women. HHT causes recurrent severe epistaxis, chronic gastrointestinal bleeding, heavy menstrual bleeding, and arteriovenous malformations in the ...
Hanny Al‐Samkari, Tracy J. Mayne, Misty Troutt, Hemant Patle, Marianne Clancy, Eric Duhaime   +5 more
wiley   +1 more source

Oral Delivery of Chitosan‐Rosmarinic Acid Nanoparticles Ameliorates Mucosal Inflammation in a Mouse Model of Colitis

Advanced NanoBiomed Research, EarlyView.
Orally administered low molecular weight chitosan–rosmarinic acid nanoparticles demonstrate potent anti‐inflammatory effects in a mouse model of colitis by scavenging reactive oxygen species, preserving intestinal barrier integrity, and modulating immune responses, underscoring their promise as an effective nanomedicine for inflammatory bowel disease ...
Afia Tasnim Rahman, Sungyeon Kang, Sangyong Jon   +2 more
wiley   +1 more source

The influence of cytokines on the complex pathology of ulcerative colitis.

Autoimmunity Reviews, 2021
H. Nakase, N. Sato, Naomi Mizuno, Yoshiko Ikawa   +3 more
semanticscholar   +1 more source