Ulcerative colitis in Nigerian children: A report of two cases and review of the literature
: Ulcerative colitis (UC) is a relapsing, idiopathic chronic inflammatory disorder of colon characterised by ulcerations of the colon with bleeding, mucosal crypt abscesses and inflammatory pseudo polyps associated with abdominal pain with tenesmus and ...
Akinyinka OO +7 more
doaj
Abstract Background and Objectives Children with medical complexity (CMC) have chronic health conditions often associated with functional limitations. CMC comprise 1%–5% of the pediatric population. In Canada, their care accounts for one‐third of pediatric health spending.
Erin Hessey +25 more
wiley +1 more source
Dextran sodium sulfate confounds causal role of periodontitis in inflammatory bowel disease
Abstract Background Emerging evidence supports a bidirectional link between periodontitis and inflammatory bowel disease (IBD). To investigate this relationship, experimental models commonly use dextran sodium sulfate (DSS) to induce colitis. However, DSS is presumed to selectively affect the colon, and its potential off‐target effects on the oral ...
Himanshi Tanwar +11 more
wiley +1 more source
Heritability of Crohn's disease and ulcerative colitis: a Swedish nationwide population-based twin study. [PDF]
Grännö O +5 more
europepmc +1 more source
Abstract Objectives Dietary therapy is often used in the management of children with inflammatory bowel diseases (IBD). Nevertheless, appropriate dietetic support and resources are not universally available, potentially leading to variable practices. This survey aimed to describe contemporary dietary practices and resourcing across IBD member centers ...
Rotem Sigall Boneh +6 more
wiley +1 more source
Effectiveness and safety of ustekinumab in pediatric Crohn's disease: Results of the REALITI study
Abstract Objectives Few approved treatments exist for children with Crohn's disease (CD). The REALITI study retrospectively assessed the effectiveness and safety of ustekinumab in real‐world clinical settings for children with CD. Methods Data were collected from the prospective ImproveCareNow (ICN) registry for pediatric patients (≥ 2 to <18 years old)
Steven J. Steiner +60 more
wiley +1 more source
Efficacy and health-related quality of life associated with second-line vedolizumab after first-line treatment with one anti-TNF in patients with ulcerative colitis: a meta-analysis of the GEMINI-1 and VISIBLE-1 trials. [PDF]
Atreya R +6 more
europepmc +1 more source
A novel diagnostic serum protein signature for pediatric inflammatory bowel disease
Abstract Objectives Diagnostic delay is common in pediatric inflammatory bowel disease (PIBD), and fecal calprotectin (FCP) is often limited by challenges with sample collection. Therefore, we aimed to identify and validate a blood‐based diagnostic protein signature of PIBD.
Charlotte Bache‐Wiig Mathisen +22 more
wiley +1 more source
The Evolution of the Management of Dysplasia in Ulcerative Colitis. [PDF]
Vickers AL, Fichera A.
europepmc +1 more source

