Results 141 to 150 of about 249,629 (285)

Fertility counseling and preservation considerations in patients with gynecologic and non‐gynecologic BRCA and Lynch‐associated malignancies

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Lynch syndrome and BRCA‐mutation associated malignancies are fortunately rare. Affected patients have an increased risk of cancer diagnosis at a young age, often significantly overlapping with their reproductive years. In helping these patients, oncologists must navigate the following areas of care: cancer prevention, impact of cancer ...
Anna Weimer, Nadeem Abu‐Rustum, David Mutch, Mauricio Cuello, Angélica Fletcher, Hextan Y. S. Ngan, Nozomu Yanaihara, Rene Pareja, Christina Fotopoulou, Kenneth Ruzindana, Ka Yu Tse, Yana Zou, Neerja Bhatla, Ting‐Chang Chang, Munanchiso Ndukwe Iheme Jr, Jalid Sehouli, Nicole Conchin, Eva Chalas, Sarikapan Wilailak, Barbara Schmalfeldt, Alexander B. Olawaiye   +20 more
wiley   +1 more source

Pediatric ulcerative colitis: current treatment approaches including role of infliximab

, 2012
Gia M Bradley, Maria Oliva-HemkerDivision of Pediatric Gastroenterology and Nutrition, Johns Hopkins University School of Medicine, Baltimore, MD, USAAbstract: Ulcerative colitis is a chronic inflammatory bowel disease that can lead to derangements in ...
Bradley GM, Oliva-Hemker M
core  

Shared Genetic Pathways Linking Oral Diseases to Gastrointestinal Disorders: An Integrative Multi‐Omics Study

iMetaMed, EarlyView.
Shared genetics pathways connect oral diseases and gut disorders. ABSTRACT Oral diseases are highly prevalent and increasingly recognized as contributors to gastrointestinal disorders. Despite clinical observations of oral–gut comorbidity, the underlying genetic architecture and causal mechanisms remain poorly understood.
Rui Zhang, Yuelan Gao, Yuyang Zhao, Wanyang Zhong, Xingxiang Duan, Yan He, Qingsong Ye   +6 more
wiley   +1 more source

Lactobacillus derived small RNAs protect against Klebsiella pneumoniae infection

iMeta, EarlyView.
This study reveals that plant‐derived natural products confer protection against carbapenem‐resistant Klebsiella pneumoniae (CRKP) infection via remodeling the gut microbiota, with Lactobacillus identified as the core beneficial genus. Mechanistically, Lactobacillus murinus (L.
Tingting Xu, Xiuying Tao, Dan Fang, Haijie Zhang, Zhiqiang Wang, Yuan Liu   +5 more
wiley   +1 more source

High‐Sugar Diet and Intestinal Diseases: A Shared Microbiota–Barrier–Immunity–Metabolism Axis in Inflammatory Bowel Disease, Food Allergy, and Colorectal Cancer

iNew Medicine, EarlyView.
ABSTRACT The global incidence of intestinal diseases—including food allergy, inflammatory bowel disease (IBD), and colorectal cancer (CRC)—continues to escalate in parallel with the expansion of the “Western diet,” within which the high‐sugar diet (HSD) has emerged as a pivotal yet under‐recognized dietary driver.
Yuchen Wang, Yajuan Wu, Huayang Sheng, Shouhong Jiang, Jinping Cheng, Ye Kuang, Miao Liu, Lei Feng, Yanan Sun, Jinzhi Duan   +9 more
wiley   +1 more source

Probiotic Intervention With Bacillus coagulans and Lactobacillus acidophilus in Small Animals Experimental Ulcerative Colitis: Insights From a Small Animal Model. [PDF]

Vet Med Sci
Shayesteh F, Shahini Shams Abadi M, Rouhi L, Doosti A, Bagheri N.   +4 more
europepmc   +1 more source

Long‐Term Outcomes of Low‐Dose Steroid Induction for Autoimmune Pancreatitis: A Multicenter Retrospective Study Identifying Risk Factors for Relapse

Journal of Hepato-Biliary-Pancreatic Sciences, EarlyView.
ABSTRACT Background Steroids are the first‐line treatment for autoimmune pancreatitis (AIP); however, the impact of lower initial doses on relapse remains unclear. Methods Ninety patients were divided into high‐dose (HD; > 0.4 mg/kg/day) and low‐dose (LD; ≤ 0.4 mg/kg/day) induction groups. The treatment response, relapse rate, and predictors of relapse
Yuhei Iwasa, Akinori Maruta, Keisuke Iwata, Hidetaka Kuroda, Shinya Uemura, Shota Iwata, Yosuke Ohashi, Naoki Mita, Hironao Ichikawa, Masahito Shimizu   +9 more
wiley   +1 more source

Ulcerative colitis in Nigerian children: A report of two cases and review of the literature

Nigerian Journal of Paediatrics
: Ulcerative colitis (UC) is a relapsing, idiopathic chronic inflammatory disorder of colon characterised by ulcerations of the colon with bleeding, mucosal crypt abscesses and inflammatory pseudo polyps associated with abdominal pain with tenesmus and ...
Akinyinka OO, Adepoju AA , Ashubu OF, Ogunbosi BO, Olatunji RB, Akere A, Orimadegun AE, Oluwasola AO   +7 more
doaj  

Design and outcome measures of clinical trials for active ulcerative colitis: a scoping review based on databases. [PDF]

Front Immunol
Zhao X, Feng C, Zhao C, Zhang R, Zhang S, Wang R, Guo J, Yan C, Chen L.   +8 more
europepmc   +1 more source

National trends in pathogen‐specific diagnoses and outcomes among hospitalizations for infectious diarrhea

Journal of Hospital Medicine, EarlyView.
Abstract Background The diagnostic evaluation of infectious diarrhea has evolved with increasing adoption of multiplex gastrointestinal nucleic acid amplification tests and changing diagnostic strategies for Clostridioides difficile. Objectives We aimed to assess changes in inpatient pathogen‐specific documentation rates and clinical outcomes on a ...
David Wong Arias, Spencer R. Goble, Mauricio Torrealba   +2 more
wiley   +1 more source