Results 151 to 160 of about 457,403 (331)
Angewandte Chemie International Edition, Accepted Article.Structural alterations in oligosaccharide structure are often associated with disease, positioning clinical glycomics an emerging tool for diagnostics. This is most commonly achieved using a controlled collision‐induced dissociation (CID) of larger oligosaccharides into fragments and measuring their mass in a mass spectrometer. Due to the complexity of
Niklas Geue +2 more
wiley +1 more source
Animal Research and One Health, EarlyView.This research innovatively illustrates baicalin’s multifaceted mechanisms in enhancing piglets’ intestinal health: modulating bile acid metabolism via probiotics, reinforcing tight junction proteins (ZO‐1/claudin), suppressing TLR4/NF‐κB‐mediated inflammation, whereas promoting growth and reducing diarrhea.
Yuhui Gao +6 more
wiley +1 more source
Arthritis &Rheumatology, EarlyView.Objective JAK inhibition (JAKi) is effective in seronegative spondyloarthropathy (SpA) spectrum disorders, but Tyk2 inhibition failed in SpA spectrum ulcerative colitis, and tofacitinib showed minimal benefit in Crohn disease, which highlights the complex role for JAK/STAT signaling in different inflammatory processes.
Sami Giryes +14 more
wiley +1 more source
Striking elevation in the incidence and prevalence of inflammatory bowel disease in a province of Western Hungary between 1977-2001 [PDF]
, 2004 AIM: An investigation into inflammatory bowel disease and colorectal cancer in Veszprem Province was conducted from 1977 to 2001. METHODS: Both hospital and outpatient records were collected and reviewed comprehensively.
Balogh, Mihály +6 more
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Clonal sharing of CD8+ T‐cells links skin and joint inflammation in psoriatic arthritis
Arthritis &Rheumatology, Accepted Article.Objective Psoriatic arthritis (PsA) is an HLA class I‐associated inflammatory arthritis that develops in up to 30% of people with psoriasis. We tested the hypothesis that skin and joint inflammation in PsA is linked in terms of CD8+ T‐cell phenotype and clonality.
Lucy E. Durham +14 more
wiley +1 more source
British Journal of Clinical Pharmacology, EarlyView.Aims Amgevita is a licensed biosimilar to adalimumab, having demonstrated high pharmacokinetic and clinical similarity to Humira. Switching to a lower‐cost medicine may elicit a nocebo effect, whereby expectations of poorer efficacy impact outcomes despite pharmacological similarity. This prospective cohort study examined clinical and economic outcomes
Louise Rabbitt +7 more
wiley +1 more source
Food Innovation and Advancesβ-ionone has various biological activities, such as anti-inflammatory, antimicrobial, and anticancer effects. The pathogenesis of ulcerative colitis is correlated with immune dysfunction, intestinal barrier damage, and gut microbiota imbalance.
Jingjing Fang +5 more
doaj +1 more source
Switching from reference infliximab to CT-P13 in patients with inflammatory bowel disease: 12 months results [PDF]
, 2017 Background: Biological agents, such as infliximab, have transformed the outcomes of patients with immune-mediated inflammatory diseases. The advent of biosimilar treatment options such as CT-P13 promises to improve the availability of biological therapy,
Argüelles Arias, Federico +7 more
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