Results 151 to 160 of about 97,018 (264)
Unmet needs in adult patients with ulcerative colitis in Spain: a real-world Adelphi Disease Specific Programme study. [PDF]
Marín-Jiménez I+8 more
europepmc +1 more source
Abstract Endoscopy is a fundamental component pediatric gastroenterology (GI), with one of its primary applications being the evaluation and management of patients with inflammatory bowel disease (IBD). However, there is variation in education and experience of gastroenterologists with pediatric IBD endoscopy, which can affect the quality of patient ...
Alexandra S. Hudson+5 more
wiley +1 more source
Abstract Objectives Early biologic initiation, dose optimization, and therapy modification based on disease phenotype are key to improving outcomes in pediatric inflammatory bowel disease (IBD). Enacting optimized therapy is often impeded by the lack of United States Food and Drug Administration (FDA) approval for pediatric use of newer advanced ...
Brad D. Constant+12 more
wiley +1 more source
Abstract The treatment options available for pediatric ulcerative colitis (UC) are challenging due to few with Federal Drug Administration approval. Newer medications approved for adults include additional biologics with differing mechanisms of action and small molecule drugs, such as Janus kinase (JAK) inhibitors.
Jessica A. Black, Brad Pasternak
wiley +1 more source
Thymoquinone Ameliorates Gut Epithelial Injury by Suppressing the JNK Signaling Pathway Based on Its Anti-Oxidant Property. [PDF]
Jia K, Wu L, Li Z, Wei T, Fan T, Xiao G.
europepmc +1 more source
Upadacitinib for difficult‐to‐treat paediatric Crohn's disease
Abstract Paediatric‐onset inflammatory bowel disease (IBD) has an enormous impact on healthcare systems as it translates to a lifetime of healthcare. Since the approval of anti‐tumour necrosis factor‐alpha agents, it has become evident that in the long journey of paediatric IBD, there is an absolute need for more treatment options.
N. Nedelkopoulou+3 more
wiley +1 more source
Ulcerative colitis increases the risk of atrioventricular block: evidence from a Mendelian randomized analysis. [PDF]
Shu W, Huang G.
europepmc +1 more source
Genital Crohn's disease in pediatrics and genetic associations
Abstract Genital edema is a rare presentation of Crohn's disease (CD), also known as metastatic CD (MCD). This may precede, co‐occur with, or follow gastrointestinal symptoms and present a diagnostic challenge. We aimed to characterize the features, clinical courses, pathogenesis, and outcomes of patients with MCD to increase understanding and promote ...
Erica Chang+5 more
wiley +1 more source
Investigating the expression of anti/pro-inflammatory cytokines in the pathogenesis and treatment of ulcerative colitis and its association with serum level of vitamin D. [PDF]
Ahmadi A+8 more
europepmc +1 more source