Ulcerative colitis in Nigerian children: A report of two cases and review of the literature
: Ulcerative colitis (UC) is a relapsing, idiopathic chronic inflammatory disorder of colon characterised by ulcerations of the colon with bleeding, mucosal crypt abscesses and inflammatory pseudo polyps associated with abdominal pain with tenesmus and ...
Akinyinka OO +7 more
doaj
Intestinal Barrier Glycosylation for Gut Physiology and Pathology
ABSTRACT The intestinal barrier is a selective structure that safeguards the body from external threats while permitting nutrient absorption and immune surveillance. It consists of the outer mucus layer, the intermediate layer of intestinal epithelial cells (IECs), and the inner layer of immune cells. The proteins in the mucus layer and within IECs are
Girak Kim, Deji Ye, Yikun Yao, Chuan Wu
wiley +1 more source
Gut‐microbiota‐brain Axis and post‐traumatic epilepsy
Abstract There has been growing evidence that perturbations in gut‐microbiota‐brain axis (GMBA) are involved in mechanisms of chronic sequelae of traumatic brain injury (TBI). This review discusses the connection between GMBA and post‐traumatic epilepsy (PTE), the latter being a common outcome of TBI.
Andrey Mazarati
wiley +1 more source
Infliximab for induction and maintenance therapy for ulcerative colitis.
P. Rutgeerts +13 more
semanticscholar +1 more source
Modulating Lysine Crotonylation in Ulcerative Colitis Maintains Mitochondrial Homeostasis
NaCr promotes KCr to impede the inflammatory progression of ulcerative colitis. KCr induces mitophagy by activating the PINK1/PARKIN pathway to restrict NLRP3 inflammasome activation, thereby decreasing the production and release of various inflammatory cytokines, such as IL‐1β and TNF‐α. KCr induces mitophagy and inhibits NLRP3 inflammasome activation
Tongtong Liu +7 more
wiley +1 more source
Gut‐Targeted Nutraceutical Delivery: Engineering Microbiome‐Responsive Nutraceutical Interfaces
ABSTRACT The gut microbiome plays a central role in maintaining host health, influencing immunity, metabolism, epithelial integrity, and the gut–brain axis. Dysbiosis of this complex microbial ecosystem is implicated in a variety of chronic diseases, including inflammatory bowel disease, metabolic syndrome, and neurological disorders.
Jeyavelkumaran Renukadevi +4 more
wiley +1 more source
Risk factors for steroid-refractory in immune checkpoint inhibitor-induced colitis: a retrospective cohort study. [PDF]
Meng K +6 more
europepmc +1 more source
(created with BioRender.com) ABSTRACT Silky fowl, a unique chicken breed, exhibits black skin, meat, and bones due to the presence of natural melanin pigments. In our study, melanin from silky fowl (MSF) was isolated using an enzymatic extraction procedure and identified as a unique natural antioxidant.
Chunhui Xu +5 more
wiley +1 more source
Effect of Chang'an decoction on ulcerative colitis by regulating T helper 17 cells and regulatory T cellsRab27 in the p53/high mobility group box 1 pathway. [PDF]
Li Z +5 more
europepmc +1 more source

