Results 261 to 270 of about 467,445 (327)

The Evolving Landscape of Immunotoxicity: Charting Mechanisms and Future Strategies for Immune Checkpoint Inhibitor Adverse Events

Med Research, EarlyView.
ABSTRACT The use of immune checkpoint inhibitors (ICIs) has significantly improved the efficacy of cancer therapy, but their associated immune‐related adverse events (irAEs) can severely compromise treatment safety. This review systematically summarizes the core mechanisms underlying irAEs, which include multi‐organ damage resulting from T‐cell ...
Anqi Lin, Keyin Zheng, Aimin Jiang, Xufeng Huang, Qi Wang, András Hajdu, Zhengrui Li, Jian Zhang, Peng Luo   +8 more
wiley   +1 more source

Artificial intelligence-based multimodal model for the identification of ulcerative colitis with concomitant cytomegalovirus colitis. [PDF]

Therap Adv Gastroenterol
Liang H, Tian Y, Ruan G, Bai X, Han W, Fu X, Wang Y, Shi J, Sun Y, Wu J, Guo C, Yang H.   +11 more
europepmc   +1 more source

Exploring Autophagy Inducing Molecules: Targeting Diverse Pathways in Alzheimer's Disease Management

Medicinal Research Reviews, EarlyView.
ABSTRACT Neurodegenerative disorders, including Alzheimer's disease (AD), impose a significant burden on society due to their progressive nature and the associated healthcare costs. Autophagy, a vital cellular degradation process, has emerged as a promising therapeutic target in these disorders.
Baljinder Singh, Shubham Mahajan, Sadikalmahdi Abdella, Rehan Khan, Sanjay Garg   +4 more
wiley   +1 more source

Plasma interleukin-22 concentration and disease activity in inflammatory bowel disease. [PDF]

Sci Rep
Cabrera C, Fernández-Llaneza D, Olsson M, Sopp C, Fehlmann T, Duncan EA, Khan E, Cairns J, Neisen J, Gehrmann U, Powell N.   +10 more
europepmc   +1 more source

Effect of the Food Matrix on the Survival to the Gastrointestinal Transit of Lacticaseibacillus rhamnosus CRL1505: A Randomized, Controlled, Crossover Study

Molecular Nutrition &Food Research, EarlyView.
We evaluated the impact of food matrix on Lacticaseibacillus rhamnosus CRL1505 survival and total quantification, carried out with strain‐specific approaches. Our results confirmed (i) the remarkable ability of CRL1505 to withstand harsh gastrointestinal conditions and (ii) the protective effect of the food matrix.
Nicola Mangieri, Viola Termine, Giorgio Gargari, Nicolò Fornasari, Michele Isotti, Susana Salva, Julio Villena, María Pía Taranto, Valentina Taverniti, Susana Álvarez, Graciela Font, Ylenia Zanchetta, Stefania Arioli, Diego Mora   +13 more
wiley   +1 more source

Ulcerative colitis and colorectal cancer: Pathogenic insights and precision strategies for prevention and treatment. [PDF]

World J Gastrointest Oncol
Catalano M, Mini E, Nobili S, Vascotto IA, Ravizza D, Amorosi A, Tonelli F, Roviello F, Roviello G, Nesi G.   +9 more
europepmc   +1 more source

Autoimmunity to Pancreatic juice in Crohn´s Disease [PDF]

, 1987
Finkbeiner, H., Lehnert, Peter, Normann, D., Otte, M., Stöcker, K., Stöcker, W., Ulrich, S.   +6 more
core  

Benefits of Nutrients and Phytonutrients in Nuts and Legumes on Platelet Aggregation Through DNA Methylation

Molecular Nutrition &Food Research, EarlyView.
Nuts and legumes contain both nutrients and bioactive compounds supporting cardiovascular health related to influencing DNA methylation. These foods are related to reducing oxidative stress, supplying methyl donors, and modulating genes involved in platelet function, such as PEAR1 and mitochondrial genes, in association with helping reduce inflammation
Siwaphorn Chaimati, Jintana Sirivarasai, Nareerat Sutjarit   +2 more
wiley   +1 more source

Research trends of intestinal barrier in ulcerative colitis: a bibliometric analysis. [PDF]

Front Med (Lausanne)
Chen Q, Chen Q.
europepmc   +1 more source

A Comprehensive Review of Food-Derived Compounds Targeting Pyroptosis for Colitis Therapy: From Effects to Mechanisms. [PDF]

J Inflamm Res
Zhao JW, Li LY, Ye FW, Zhao WY.
europepmc   +1 more source