Results 121 to 130 of about 672,024 (402)

Intestinal Acid Sphingomyelinase Protects From Severe Pathogen-Driven Colitis [PDF]

, 2019
Inflammatory diseases of the gastrointestinal tract are emerging as a global problem with increased evidence and prevalence in numerous countries. A dysregulated sphingolipid metabolism occurs in patients with ulcerative colitis and is discussed to ...
Becker, Katrin A., Ebel, Jana-Fabienne, Hose, Matthias [u.v.m.], Japtok, Lukasz, Klopfleisch, Robert, Meiners, Jana, Palmieri, Vittoria, Schumacher, Fabian, Yusuf, Ayan Mohamud, Zöller, Julia   +9 more
core   +1 more source

Intestinal microbiome analyses identify melanoma patients at risk for checkpoint-blockade-induced colitis

Nature Communications, 2016
The composition of the intestinal microbiota influences the development of inflammatory disorders. However, associating inflammatory diseases with specific microbial members of the microbiota is challenging, because clinically detectable inflammation and
K. Dubin, M. Callahan, Boyu Ren, R. Khanin, A. Viale, Lilan Ling, Daniel No, Asia Gobourne, E. Littmann, C. Huttenhower, E. Pamer, J. Wolchok   +11 more
semanticscholar   +1 more source

Polydopamine Nanodots Ameliorate Inflammatory Bowel Disease by Restoring Redox Homeostasis and Intestinal Microenvironment

Advanced Science, EarlyView.
A novel melanin‐based therapeutic composed of ultrasmall polydopamine nanodots is employed as an efficient oral formulation for the targeted treatment of inflammatory bowel disease. The potential therapeutic mechanism of polydopamine nanodots mainly involves the elimination of excessive oxidative stress, the reduction of ROS‐mediated proinflammatory ...
Zhen Ding, Xingfu Bao, Ying Zhao, Lin Bai, Jinming Zhang, Chengjing Xu, Tianyan Chen, Shuang Dai, Yufu Liu, Min Hu, Meng Qin, Zhen Liu   +11 more
wiley   +1 more source

Clostridium difficile colitis in patients after kidney and pancreas-kidney transplantation [PDF]

, 2004
Limited data exist about Clostridium difficile colitis (CDC) in solid organ transplant patients. Between 1/1/99 and 12/31/02, 600 kidney and 102 pancreas–kidney allograft recipients were transplanted.
Basu, A, Fung, JJ, Keven, K, Marcos, A, Re, L, Shapiro, R, Simmons, RL, Starzl, TE, Tan, H   +8 more
core   +1 more source

Role of Enteric Glia as Bridging Element between Gut Inflammation and Visceral Pain Consolidation during Acute Colitis in Rats [PDF]

, 2021
Elena Lucarini, Luisa Seguella, Martina Vincenzi, Carmen Parisio, Laura Micheli, Alessandra Toti, Chiara Corpetti, Alessandro Re, Silvia Squillace, Daniela Maftei, Roberta Lattanzi, Carla Ghelardini, Lorenzo Di Cesare Mannelli, Giuseppe Esposito   +13 more
openalex   +1 more source

TREM2 Drives Neutrophil Extracellular Traps‐Induced Dendritic Cell Maturation and Contributes to Lupus Progression

Advanced Science, EarlyView.
TREM2 recognizes NETs‐derived MPO to promote DC maturation and antigen presentation, thereby exacerbating the autoimmune response in SLE. Mechanistically, TREM2 activation triggers the DAP12/SYK/ERK cascade and enhances NETs internalization by DCs, which in turn activates the cGAS/STING signaling pathway.
Jingxian Shu, Jiabi Liang, Linda Zeng, Shuping Zhong, Xueling Fang, Yating Xu, Yongjian Wu, Xi Huang   +7 more
wiley   +1 more source

Dysbiotic signatures and diagnostic potential of gut microbial markers for inflammatory bowel disease in Korean population

Scientific Reports
Fecal samples were collected from 640 individuals in Korea, including 523 patients with IBD (223 with Crohn’s disease [CD] and 300 with ulcerative colitis [UC]) and 117 healthy controls.
Hyun Sik Kim, Shin Ju Oh, Byung Kwon Kim, Ji Eun Kim, Bo-Hyung Kim, Young-Kyu Park, Bo-Gie Yang, Jae-Yun Lee, Jin-Woo Bae, Chang Kyun Lee   +9 more
doaj   +1 more source

Development of colon cancer after liver transplantation for primary sclerosing cholangitis associated with ulcerative colitis [PDF]

, 1990
Between February 26, 1981, and July 30, 1987, 36 patients underwent orthotopic liver transplantation for primary sclerosing cholangitis associated with ulcerative colitis.
Higashi, H, Kakizoe, S, Marsh, JW, Starzi, TE, Tzakis, A, Yanaga, K   +5 more
core   +1 more source

Cyanidin-3-O-Glucoside Supplement Improves Sperm Quality and Spermatogenesis in a Mice Model of Ulcerative Colitis [PDF]

, 2022
Yuhang Xiao, Baojun Xu, Matteo Bordiga, Haiwei Li, Fabiano Travaglia, Shun Bai, Jiali Chen, Weibin Bai   +7 more
openalex   +1 more source

Collagenous Colitis.

Internal Medicine, 1995
Collagenous colitis is characterized clinically by chronic watery diarrhea and pathologically by colonic mucosal subepithelial collagen deposition. We report a 72-year-old woman who had collagenous colitis associated with chronic watery diarrhea.
A, Katanuma, T, Kodama, T, Tamaki, S, Katabami, K, Yamashita, J, Itoh, K, Imai   +6 more
openaire   +3 more sources