β7 Integrin Inhibition Can Increase Intestinal Inflammation by Impairing Homing of CD25hiFoxP3+ Regulatory T Cells. [PDF]
, 2020 Background & aimsIntegrin α4β7 mediates lymphocyte trafficking to the gut and gut-associated lymphoid tissues, a process critical for recruitment of effector lymphocytes from the circulation to the gut mucosa in inflammatory bowel disease (IBD) and ...
Eckmann, Lars +5 more
core +1 more source
Endoscopic scores for inflammatory bowel disease in the era of 'mucosal healing'. old problem, new perspectives [PDF]
, 2016 The importance of the endoscopic evaluation in inflammatory bowel disease (IBD) management has been recognized for many years. However, the modalities for reporting endoscopic activity represent an ongoing challenge.
Corleto, Vito Domenico +5 more
core +1 more source
Immune checkpoint inhibitor-induced colitis: A comprehensive review
World Journal of Clinical Cases, 2019 Immune checkpoint inhibitors (ICIs) are monoclonal antibodies that target down-regulators of the anti-cancer immune response: Cytotoxic T-lymphocyte antigen-4, programmed cell death protein-1, and its ligand programmed death-ligand 1.
Aniruddh Som +6 more
semanticscholar +1 more source
Current review of genetically modified lactic acid bacteria for the prevention and treatment of colitis using murine models [PDF]
, 2015 Inflammatory Bowel Diseases (IBD) are disorders of the gastrointestinal tract characterized by recurrent inflammation that requires lifelong treatments.
Azevedo, Vasco +7 more
core +1 more source
Scientific ReportsFecal samples were collected from 640 individuals in Korea, including 523 patients with IBD (223 with Crohn’s disease [CD] and 300 with ulcerative colitis [UC]) and 117 healthy controls.
Hyun Sik Kim +9 more
doaj +1 more source
Optimization of Ensemble Supervised Learning Algorithms for Increased Sensitivity, Specificity, and AUC of Population-Based Colorectal Cancer Screenings [PDF]
arXiv, 2017 Over 150,000 new people in the United States are diagnosed with colorectal cancer each year. Nearly a third die from it (American Cancer Society). The only approved noninvasive diagnosis tools currently involve fecal blood count tests (FOBTs) or stool DNA tests.
arxiv
Proceedings of the National Academy of Sciences of the United States of America, 2018 Significance Stress cannot be avoided in the present competitive world, and chronic stress is associated with detrimental effects on physical health, including the progression of inflammatory bowel disease (IBD).
Xinghua Gao +16 more
semanticscholar +1 more source
Infammatory bowel disease-associated ubiquitin ligase RNF183 promotes lysosomal degradation of DR5 and TRAIL-induced caspase activation [PDF]
, 2019 Open access.金沢大学医薬保健研究域医学系journal ...
30580394 +10 more
core +2 more sources
Colonic obstruction after ingested gravel and stone
Asian Journal of Surgery, 2012 This case concerns a 10-year-old boy with a history of behavioral abnormality that arrived at our surgical emergency room with acute abdominal discomfort.
P.V. Narayanan, M.K. Balachandran
doaj +1 more source
Medical trauma in young adults with inflammatory bowel disease: The role of trauma-informed care
Health Care TransitionsMedical trauma is a profound concern for those with chronic conditions like inflammatory bowel disease (IBD), especially young adults. This trauma, arising from both the disease itself and necessary medical interventions, manifests as an accumulation of ...
Amy K. Bugwadia +6 more
doaj