Results 121 to 130 of about 302,337 (268)

Deciphering the catalytic and pharmacological mechanisms of Coptis chinensis herbzymes to renovate intestinal microenvironment for colitis alleviation

BMEMat, EarlyView.
The synthesized CCzymes possess both antioxidant enzyme activity and pharmacological properties inherent to Coptis chinensis. By their antioxidant enzyme activity, CCzymes can attenuate oxidative stress within the inflammatory region of ulcerative colitis (UC), while their pharmacological activity acts on macrophage polarization and the intestinal ...
Zhichao Deng, Can Li, Yujie Zhang, Yuanyuan Zhu, Chenxi Xu, Bowen Gao, Mingxin Zhang, Martina H. Stenzel, Kelong Fan, Mingzhen Zhang, Yanyan Jiang   +10 more
wiley   +1 more source

Effects of Rosemary and husk on hemogram and some biochemical parameters during treatment of ulcerative colitis in rats [PDF]

, 2019
Magdy Amer, Rasha M. Saleh, Mayada Rashad   +2 more
openalex   +1 more source

Nutritional Content, Phytochemical Composition, and Physicochemical Properties of Different Quinoa (Chenopodium quinoa Willd.) Seed Varieties

Cereal Chemistry, EarlyView.
ABSTRACT Background and Objectives Quinoa (Chenopodium quinoa Willd.) is a pseudocereal with documented benefits for human health. The macronutrient composition and phytochemical content of the grain are known to vary depending on the variety and the growing location.
Vassilios Raikos, Shirley De Lima Sampaio, Helen E. Hayes, Gary J. Duncan, Donna Henderson, Nicholas J. Vaughan, Wendy R. Russell, Madalina Neacsu   +7 more
wiley   +1 more source

Nanogel‐Mediated Immunotherapy to Tackle Cancer and Inflammatory Diseases

ChemistryEurope, EarlyView.
Nanogels formed through self‐assembly, microemulsion, or precipitation polymerization method enable precise delivery of immunotherapeutic factors and immune cell targeting, thus effectively modulating immune responses. This review highlights recent advances in stimuli‐responsive nanogel design, underlying mechanisms, and their potentials to tackle ...
Ziwen Zhang, Jinxia Wang, Guang‐Zhi Jin, István Bányai, Dzmitry Shcharbin, Ivan Stoikov, Mingwu Shen, Xiangyang Shi   +7 more
wiley   +1 more source

Integrated Multi-Omic Analysis Identifies Altered Colonic Brush Border Profile as a Key Feature of Microscopic Colitis. [PDF]

United European Gastroenterol J
Guagnozzi D, Gonzalez-Castro AM, Zabana Y, Fernández-Bañares F, Münch A, Tristan E, Lozano JJ, Sidorova J, Lobo B, Alonso-Cotoner C, Exposito E, Lucendo AJ, Landolfi S, Benages A, Llerena-Castro R, Castillo Cejas MD, Dot J, Santos J, Vicario M.   +18 more
europepmc   +1 more source

Isoform Specificity of a Compound Targeting Actin Filaments Containing Tropomyosin Tpm1.8/1.9

Cytoskeleton, EarlyView.
ABSTRACT The unbranched actin filaments in mammalian cells are usually composed of co‐polymers of a specific tropomyosin isoform with actin. Genetic manipulation has revealed that the tropomyosins largely define the functional properties of actin filaments in an isoform‐specific, non‐redundant manner.
Jeff Hook, Edna C. Hardeman, Peter W. Gunning   +2 more
wiley   +1 more source

Pembrolizumab-Induced Colitis With Concurrent Capecitabine in Triple-Negative Breast Carcinoma: A Case Report. [PDF]

Cureus
Kafka W, Frandah W, Diks J.
europepmc   +1 more source

EFFECTS OF BRAIN-DERIVED NEUROTROPHIC FACTOR AND ITS SIGNALING PATHWAY ON SENSORY NEURONAL ACTIVATION DURING COLITIS

, 2015
Fiza Hashmi
openalex   +2 more sources

Clinical Safety of Extended Interval Dosing of Nivolumab in Patients with Melanoma

Clinical Pharmacology &Therapeutics, EarlyView.
Extended interval dosing regimens of immune checkpoint inhibitors have been implemented widely. However, their approval was mainly based on pharmacokinetic modeling and simulations. Consequently, comparative safety data of extended interval dosing regimens in a real‐world setting are limited.
Ruben Malmberg, Maaike M. Hofman, Fatima Ashad, Alaa Daloul, Stefani Oosterveld, Edwin A. Basak, Esther Oomen‐de Hoop, Astrid A. M. van der Veldt, Arjen Joosse, Roelof W. F. van Leeuwen, Ron H. J. Mathijssen   +10 more
wiley   +1 more source

Vaso-Occlusive Thrombotic Ischemic Colitis Presenting With Large-Volume Hematochezia in Sickle Cell Beta⁺-Thalassemia. [PDF]

ACG Case Rep J
Asfaw M, Aduli F, Homayounieh M, Santiago Gonzalez JC, Shokrani B, Fadul S.   +5 more
europepmc   +1 more source