Results 121 to 130 of about 199,144 (206)
IJU Case Reports, EarlyView.ABSTRACT Introduction Enfortumab vedotin (EV) has been reported to cause skin toxicity in some patients. We report a rare case of toxic epidermal necrolysis (TEN) induced by EV and complicated by severe gastrointestinal (GI) bleeding. Case Presentation A 70‐year‐old man with recurrent urothelial carcinoma developed a trunk rash at 16 days after EV ...
Aika Matsuyama +9 more
wiley +1 more source
iMetaOmics, EarlyView.The PANDA pipeline for colorectal cancer (CRC) analysis integrates metabolomic data from LC‐MS with machine learning techniques to classify CRC stages and predict biomarkers. Initially, the raw metabolomic data is processed using partial least squares discriminant analysis (PLS‐DA) to reduce dimensionality and highlight key features.
Rui Xu +8 more
wiley +1 more source
Selective expansion of gut antibiotic resistome and underlying pathways involved in type 1 diabetes
iMetaOmics, EarlyView.Selective expansion of gut antibiotic resistance genes (including glycopeptides, tetracyclines, macrolide‐lincosamide‐streptogramins, and beta‐lactams) was observed in type 1 diabetic rats. Interestingly, a similar expansion of gut antibiotic resistome occurred in diabetic patients.
Guozhu Ye +6 more
wiley +1 more source
iMetaOmics, EarlyView.In this study, we explored the therapeutic effects of Parabacteroides goldsteinii (P. goldsteinii) on colitis and its underlying mechanisms. Our results indicate a significant reduction of P. goldsteinii in the stools of inflammatory bowel disease patients. We demonstrate the therapeutic potential of P.
Fujian Qin +7 more
wiley +1 more source
Skin microbiome engineering: Challenges and opportunities in skin diseases treatment
iMetaOmics, EarlyView.The skin microbiome plays a crucial role in skin health, influencing barrier integrity, immune responses, and disease susceptibility. Various interventions can reshape the microbiome, broadly categorized into targeted and untargeted approaches. Targeted strategies, such as phage therapy, engineered bacteria, and phage lysins, selectively modulate ...
Yiang Lyu, Juntao Shen, You Che, Lei Dai
wiley +1 more source
Interdisciplinary Medicine, EarlyView.We introduced the basic characterization and isolation methods of PEVs, reviewed the PEVs‐related articles pertaining to disease therapy and drug delivery system, and summarized the drug loading methods, storage techniques, and engineering modification strategies of the carrier, to establish a safer, more efficient and more affordable approach for ...
Jichun Yang +14 more
wiley +1 more source
Engineered strategies for the allergic disease therapy
Interdisciplinary Medicine, EarlyView.Allergic diseases exist widely across the globe and now there are very limited therapeutics for the treatment of these diseases. In this review, we summarize the recent advances in engineering strategies including nanoemulsion and hydrogel to improve the therapeutic efficacy of allergen‐specific immunotherapy with decreased side effects and long‐term ...
Yun Tian +4 more
wiley +1 more source
Interdisciplinary Medicine, EarlyView.This article evaluates the therapeutic potential of extracellular vesicle‐like particles derived from Chinese herbal medicine (CHM‐EVLP) for a range of diseases. It underscores the significance of traditional Chinese medicine in the development of innovative formulations.
Ying‐qi Cao +6 more
wiley +1 more source
Illuminating Immunity: A Systematic Review of Immune Cell Autofluorescence
Journal of Biophotonics, EarlyView.ABSTRACT Immunophenotyping provides valuable prognostic and diagnostic information, but is technically complex and expensive. The assessment of autofluorescence is label‐free and provides complex information on cell identity. However, research on its application to immunophenotyping has been heterogenous.
Aline Knab +4 more
wiley +1 more source